Points Flashcards

(40 cards)

1
Q

Exclusive bile secretion

A

Nafcillin
cefeperazone
cefetriazone
glycyclines

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2
Q

Thrombophelebitis causing drugs

A

Vancomycin

cephlosporins

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3
Q

kinecterus causing drugs

A

cephalosporins and sulfonamides

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4
Q

Drugs uses against febrile neutropenia

A
cephlosporin 4 (cefeprime)
antipseudomonals drugs
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5
Q

pseudomebranous colitis causing drug

A

amipcillin and clindamycin

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6
Q

pseudomembranous colitis treatment

A

vancomycin and mtronidazole

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7
Q

DOC of upper respiratory tract infections

A

ampicillin, macrolides and cotrimoxazole also used for upper respiratory infection

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8
Q

DOC for lower respiratory tract infections

A

2nd genr cephalosporins

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9
Q

UNcomplicated lower unrinary tract infections DOC

A

fosfomycin,

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10
Q

DOC for COMpliacted UTI

A

4th gen cephalosporins

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11
Q

effective against pneumococci

A

cefetixme , cefetriaxone, cefetazone

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12
Q

parenterally not given drugs (cephlosposrin)

A

Fix-Lex-calor

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13
Q

Mthyl-thiol containg drugs-

A

cefemandole, cefetetan, cefeprozone

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14
Q

Hepatic encephalopathy and endocaridtis drug

A

neomycin

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15
Q

DOC for whopping cough

A

erthromycin

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16
Q

emperic therapy for community acquired pneumonia

A

MAcrolides

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17
Q

3A4 activation and inhibition

A

activates carbapezamine metabolism

is inhibitied by chloramphenicol and streptogramins

18
Q

3A4 inhibitors

A

chloramphenicol and steptogramins

19
Q

NAT-2 metbaolism

A

isoniazid
hydralazine/procinamide
sulfonamides

20
Q

Isonizaid build up due to NAT-2 dysfunction

A

–> neurotoxcitiy

hepatotxicity

21
Q

hydralazine/procinamide build up AE

22
Q

sulfonamide from NAT-2 AE

A

SLE, hypersensitvity , hemolytic anemia

23
Q

non small cell lung carcinoma –> whats fucked up ?

A

EGFR (respond to gifitinib )

24
Q

CYP2D6

A

metabolizes antidepressant/antipsychotics/antiarthmetics/analgesics

25
CYP2D19
clopidogrel converter
26
CYP2c9
S-warfarin converter
27
Y12 receptor for ?
clopidogrel
28
CHronic alcohol use inducer or inhibitor of CYP ??
chronic --> inducer | Acute --> inhibitor
29
gingkos biloba
inhibits plateltes aggregation
30
difference between exudate and transudate >
Exudate only in inflammation and has protein
31
B-lactamASES releasing organism
Staph-
32
Effective EMPERIC treatment of endocarditis
penicillin + aminoglycoside
33
Penicillin V given IV, orally, rectal, IM ?
Orally (for mild to moderate )
34
Serious infection of succeptible organism use ?
Antipseudomonal species ??maybe
35
what drug is insufficient in prostate and eyes ?
Penicillin
36
parenteral admin only for ?
cephlopsorins except (cefexime, cefecalor, cefelexin )
37
drug that can be used in CF patients
Monobactam, ciprofloxacin(inhalation for P.aeruginosa)
38
Nephrotoxicity caused by topical use of a drug
Bacitracin
39
Drugs that cause neutropenia
Clindamycin, nafcillin
40
P.Aeruginosa coverage?
ceftazidime, cefperazone, carbecillin,piperacillin,ticaracillin, Ciprofloxacin(inhalation with CF patients) polymixin B(parenternal salvage Carbapenems(except ertapenem) Monobactum