Polar amino acid

Question 1

The abbreviation of serine?

Answer 1

Ser/S

Question 2

The R group of S contain?

Answer 2

The R group of Serine contain polar hydroxyl group

Question 3

Can serine be ionizable?

Answer 3

No,it can’t lose (H+)(not titrable)

Question 4

The abbreviation of Threonine?

Answer 4

Thr/T

Question 5

The R group of Thr contain?

Answer 5

Polar Hydroxyl group

Question 6

In S and T in which carbon of R group the hydroxyl group attach?

Answer 6

In serin and Threonine the (oH)attach on B_carbon

Question 7

How many assymetric carbon in T?

Answer 7

2 assymetric carbon(الفا وبيتا)

Question 8

What is the polar uncharged amino acid that has two chiral (assymetric)carbon?

Answer 8

Threonine

Question 9

The only two amino acids that contain two assymetric carbon(الفا وبيتا)?

Answer 9

Isoleucine(Ile/I),Threonine(Thr/T)

Question 10

The abbreviation of Tyrosine?***

Answer 10

Tyr/y

Question 11

The polar amino acid that derived from phe(phenylalanine)?

Answer 11

Tyr/y🙃(Tyrosine).

Question 12

The R group in Y contain?

Answer 12

Phenol group (the name of amino acid:Tyrosine).

Question 13

The polar aromatic amino acid?

Answer 13

Y/Tyr🙃

Question 14

The amino acids that contain aromatic side chain?

Answer 14

Phenylalanine(Phe/F), Tryptophan(Trp/W),Tyrosine(Tyr/Y)

Question 15

Is Tyr/Y titrable?

Answer 15

Yes,(at pH=7,OH protonated and Neutral)and(at PH bigger than 10.07, O- deprotonated and negative).

Question 16

The abbreviation of Cysteine?

Answer 16

Cys/C

Question 17

R in Cys contain?

Answer 17

Sulfohydryl(Thiol)group

Question 18

R in Cys contain?

Answer 18

Sulfohydryl(Thiol)group

Question 19

The polar amino acid that contain sulfer?

Answer 19

Cys/C(Cysteine)

Question 20

The amino acids that contain sulfer?

Answer 20

Methionine(Met/M), Cysteine(Cys/C)

Question 21

Is sulfer reactive in Cys?

Answer 21

Yes, cause it’s terminal (but remember sulfer in Met not reactive cause it’s within the skeleton)🤝

Question 22

Is cycteine titrable?

Answer 22

Yes,(at PH=7, SH protonated and Neutral)and(at PH higher than 8.18, S- deprotonated and negative.

Question 23

The abbreviation of Asparagine?***

Answer 23

Asn/N

Question 24

Side chain in (Asn/N)?

Answer 24

In Asparagine the R group contain (polar amide group at B_carbon)(CONH2)

Question 25

Is N titrable?

Answer 25

No, Asn(Asparagine) not titrable

Question 26

The abbreviation of Glutamine?***

Answer 26

Gln/Q

Question 27

R group in (Gln/Q)?

Answer 27

Contain polar amide(CONH2)

Question 28

Q titrable?

Answer 28

No,Glutamine not titrable

Question 29

Which side chain is longest in Asn or Gln?

Answer 29

In Glutamine side chain is longer(and remember in Asparagine amide attach on( B_carbon ),but in (Q) it attach on( y_carbon)

Question 30

When two Cystein undergo oxidation will form?and what's the name of bond?

Answer 30

Cystine, covalent bond (disulfide bond)(this bond stabilize the structure of the protein)(and remember Cystine not amino acid).

Question 31

What are the acidic amino acids?

Answer 31

Aspartic acid and Glutamic acid(they have acidic R group which is negatively charged at PH=7)

Question 32

The abbreviation od Aspartic acid?***

Answer 32

Asp/D

Question 33

The abbreviation of Glutamic acid is?***

Answer 33

Glu/E

Question 34

Asp and Glu have side chain contain?

Answer 34

Polar carboxyl group(but in Aspartic acid (COOH) attach at B_carbon)and in Glutamic acid attach at(y_carbon), so R group in( E) is longer than( D).

Question 35

Aspartate is?

Answer 35

Deprotonated form of Aspartic acid and is precursor for Asparagine.🥲

Question 36

Glutamate is?

Answer 36

Deprotonated form of Glutamic acid and precursor for Glutamine.🥲

Question 37

The basic amino acids are?

Answer 37

Lysine/Histidine/Arginine

Question 38

The abbreviation of Lysine?***

Answer 38

Lys/k

Question 39

R group in Lysine(Lys/k) contain?

Answer 39

Amine(NH3+)(the name of side chain:Butyl_ammonium)

Question 40

The abbreviation of Histidine?

Answer 40

His/H

Question 41

The R group in (His) contain?

Answer 41

Imidazol ring

Question 42

The basic amino group that has pka=6 close to physiologic PH and work as abuffer inside the body?

Answer 42

Histidine(basic structure with asidic pka).

Question 43

What is the factor that makes protein work as abuffer?

Answer 43

If it has big amount of histidine(high content) (just like hemoglobin).

Question 44

What is the abbreviation of Arginine?***

Answer 44

Arg/R

Question 45

R group in Arg contain?

Answer 45

Guanidino group

Question 46

The charge of basic amino acid at PH=7 will be?

Answer 46

Positive charge🙃

Question 47

Are acidic and basic amino acid ionizable?

Answer 47

Yes