Pols Flashcards

(54 cards)

1
Q

Both meiosis and mitosis in human cells starts with “2n” cells. After mitosis, are daughter “1n” or 2n

A

2n

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2
Q

Both meiosis and mitosis in hunan cells starts with 2n cells. After meiosis, are the daughter cells 1 n or 2n

A

1n

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3
Q

In order to mate, yeast need to have different ? Types

A

Mating

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4
Q

What are the two methods of signaling we discussed in class that occur through cell to celll contact

A

Gap junction and receptor to ligand

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5
Q

What is the generic came for the molecule that binds to a receptor

A

LIgands

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6
Q

Describe autocrine signaling

A

self signaling

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7
Q

Describe paracrine signlings

A

One close by signaling short distance

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8
Q

describe endocrine signaling

A

signaling lots of cells long distances

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8
Q

describe endocrine signaling

A

signaling lots of cells long distances

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8
Q

describe endocrine signaling

A

signaling lots of cells long distances

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9
Q

What is a cytokine

A

small protein that d3eals with the growth of cells

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10
Q

Humans have 23 pairs of homologous chromosomes. Which chromosomes are consider somatic/ autosomal

A

first 22

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11
Q

Humans have 23 pairs of homologous chromosome, what are the names of the sex chromosomes?

A

XY

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12
Q

Compare chromosome with chromatin

A

Chromatin is unraveled DNA and chromosome ar supercondensed DNa in a double helix structure for correct separtion during cell replication.

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13
Q

Where along the chromosome would you find repetitive telomeric sequence

A

The ends

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14
Q

What type of retitive DNA sequence is found at the site where sister chromatids are held together?

A

Centromere

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15
Q

Interphase encompasses what three stages of the cell cycle?

A

G1,S,G2

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16
Q

Mitosis can be broken down into what four phases

A

Prophase, metaphase, anaphasr, and telophase

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17
Q

In what phase of mitosis does DNA fist condense?

A

Prophase

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18
Q

What phase of mitosis follows the M checkpoint

A

Anaphase

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19
Q

In what phase of mitosis do the siter chromatide line up down the center of the cell

A

Metaphse

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20
Q

Name two things a cell check on before proceeding through the G1 checkpoint

A

DNA damage and Nutuients

21
Q

What molecule binds to a cell receptor in initiate pathway tha eventuallly lead to cyclin D accumulation

A

Cycline- dependent Kinases

22
Q

Rb is a tumor suppressor, what modification causes Rb to relase the E2 transcription factor

A

Low number of phosphate groups

23
Do one or both copies of proto-oncogenes need to be mutated to lead to sustain cell prolieferation signals
just one
24
Do one or both copies of tumor suppressor genes need to be nutated to lead to loss of cell cycle checkpoints
both
25
The pro- and Anti-apoptotic protein balance occurs at which cellular organelle?
Mitochondria
26
What is the name of the enzyme that can lengthen telomere sequences
Telomerase
27
ANiogenesis refers to the process of building which featre in the body
blood cessels
28
New tumors tha tgrow in differnt tissures than where the primary tumor occurred are called what m word?
metastatic tumor
29
What cell type can become carcinomas
Squamous cells
30
Do cell differentiate or de-d ifferentiate during the epithelial-to- mesenchymal transition
Differentiate
31
During which stage to tetrads line up down the center of cells, meiosis I or mesiosis 2
meiosis 1
32
The central dogma states DNA- RNA- Protein. Genotype describe which of these three macromolecules
DNA
33
What is the difference between a carcter and a trait
Characcteristic is phenotype f shown things, train is the feature of each like the different eye colors
34
What genotypes do the F1 genration have if organisms with genotypes DD and dd are crossed
Heterozyfus for Dd
35
In a monohybrid cross, what are the espected ratios of the genotypes of the offspring
1:0 100% heterozygous for Dd
36
What process is used during meiosis ! to create novel, mosaic chromosome structures?
Crossing over events
37
Crosses of snapdragons with red and white flowers result in offspring with what color of flowers
Pink flower
38
What form of t non-mendelian genetics causes the AB blood type, incomplete dominance or co-dominance
Co-dominance
39
What blood types would be possible in the child with parents of type O and type AB blood
Type A and type B
40
Hemophilia is an X-linked genetic disease. Are most hemophiliacs male or female
male
41
WHat is a point mutation
1 nucleotide is replaced with another nucleotide, 1 nucleotide changes, any copies of DNA using the mutated stand as template will also have mutation
42
Indel mutaion cuase short ? and ?
Insertion and deletion
43
Some polumerases can also destroy DNA in a 3' to 5; direction if they have
Exonulease
44
What kind of electromagnetic wave can cause pyrimidine dimers
UV
45
name mone kind of electomagneic wave that can cuase double-standed DNA breaks
X-ray
46
What genetic tool do scientist use to cuase a doubl.e-stranded DNA break exactly where the target
CRISPR
47
NHEJ is prone to what kind of mut8ion when attempyin yo repain a DNA double-standed break
Indel mutation
48
HR makes use of what DNa sequence to repair a DNA double-stranded break
Homologous chromosome sequence
49
Can molecular oxygen pass through a phospholipid bilayer without a channel or pump?
yes
50
Can carbon dioxide pass through a phospholipid bilayer without a channel or pump?
yes
51
Can water pass through a phospholipid bilayer without a channel or pump?
no
52
Can glucose pass through a phospholipid bilayer without a channel or pump?
no