Polymyositis, Dermatomyositis, Inclusion Body Myositis

Question 1

Initial presentation of PM and DM

Answer 1

Proximal muscle weakness, progressive and symmetric

Question 2

Blue-purple discoloration on the upper eyelids with edema

Answer 2

Heliotrope rash

Question 3

Erythema of the knuckles with raised violaceous scaly eruption resulting to scaling of the skin

Answer 3

Gottron rash

Question 4

Rash on back and shoulders

Answer 4

Shawl sign

Question 5

MC inflammatory myopathy in patients >50 years old

Answer 5

Inclusion body myositis

Question 6

Definite diagnosis of IBM

Answer 6

Muscle Biopsy

Question 7

80% of patients positive for this antibody have ILD

Answer 7

anti-JO1

Question 8

Most sensitive enzyme which parallels disease activity

Answer 8

CK

Question 9

Diagnostic of DM even in the absence of inflammation

Answer 9

Perifascicular atrophy

Question 10

Least favorable prognosis among all myopathies

Answer 10

IBM (resistant to immunosuppressive therapy)

Question 11

Treatment of choice

Answer 11

Prednisone 1mkd and tapered over 10 weeks

DM>PM