POM to P Supply of Infections in Community Pharmacy Flashcards

(31 cards)

1
Q

What is amorolfine 5% nail lacquer used for?

A

For mild fungal infections affecting the tips/sides of up to 2 toenails only

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2
Q

When should you refer a patient who wishes to buy amorolfine 5% nail lacquer?

A

Diabetic
Immunocompromised
<18 years old
If >2 nails are affected
If the whole nail/bottom of the nail is affected

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3
Q

What is the presentation of a fungal infection of a toenail?

A

Crumbly/flaky nail
Thickening of nail
Discolouration
Nail separating from nail bed
Yellow/white colour
Brittle

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4
Q

What happens to amorolfine 5% nail lacquer when it is applied?

A

The solvent evaporates and leaves a highly conc. deposit which penetrates into the nail

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5
Q

What is the mechanism of action of amorolfine?

A

It is a topical antifungal which inhibits sterol synthesis. preventing the fungal cell membrane from forming

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6
Q

What is the dosing of amorolfine 5% nail lacquer?

A

Must be applied ‘like nail polish’ once a week at the same day for a min. of 9 months

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7
Q

What are some counselling points to consider for amorolfine 5% nail lacquer?

A

Nail must be filed down/cleaned before application
Do not wipe any excess nail lacquer onto the neck of the bottle to avoid contamination
Avoid contact with eyes/ears
Applicator must be cleaned after every use
Debris from the infected nail can restart another infection e.g. athletes foot - treat with e.g. terbinafine/clotrimazole

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8
Q

What are some contraindications for the use of amorolfine 5% nail lacquer?

A

<18 years old
Avoid if pregnant/breastfeeding
If any allergies to amorolfine

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9
Q

What is chloramphenicol used for?

A

Acute bacterial conjunctivitis for >2 years old

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10
Q

What is the dosing of chloramphenicol?

A

1 drop every 2h for the first 2 days, then 1 drop every 4h for the next 3 days.

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11
Q

How many times a day should a patient apply chloramphenicol eye ointment?

A

3-4 times a day

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12
Q

When should you refer a patient who wishes to buy chloramphenicol?

A

<2 years old
Pregnant/breastfeeding
Photophobia
Blurred/cloudy vision
Pain
Bloody discharge/bloodshot eye
No response after 2 days of treatment
Distorted pupils
Swelling of eye
Using other eye drops
Restricted eye movement
Bone marrow suppression present
If they wear contact lenses

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13
Q

What are the counselling points for chloramphenicol?

A

Bathe eyes in lukewarm water to remove discharge
Condition is self-limiting
Use 1 bottle per infected eye
Avoid sharing bottles if >1 person affected
Avoid sharing towels/facecloths/eye cosmetics
Wash/dry hands before/after using eye drops
Store in fridge and discard after 5 days

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14
Q

What are the symptoms of acute bacterial conjunctivitis?

A

Inflamed watery pink eye
Burning/gritty around the eye (no pain)
Dried crusts when waking up
Yellow/sticky discharge

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15
Q

What are the symptoms of malaria?

A

Fever
Sweats/chills
Muscle pains
Lethargy
Diarrhoea
Vomiting

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16
Q

What is contained in Maloff Protect?

A

Atovaquone 250mg and proguanil hydrochloride 100mg

17
Q

How should Maloff Protect be taken for malarial prophylaxis?

A

1 tablet daily 1-2 days before travelling, during travel, and 1 week after travel

18
Q

How should you take the Maloff Protect tablet?

A

At the same time everyday with food/milky drink

19
Q

What should a patient do if they vomit within 1h after taking Maloff Protect?

A

Take another tablet immediately

20
Q

What are the contraindications for Maloff Protect?

A

<18 years old
<40kg
Travelling for >12 weeks
Renal/hepatic impairment
Pregnant/breastfeeding

21
Q

What is contained in avloclor?

A

Chloroquine 250mg

22
Q

How should avloclor be taken for malarial prophylaxis?

A

1 tablet weekly before travel, during travel, and 4 weeks after travel

23
Q

What is contained in paludrine?

A

Proguanil hydrochloride 100mg

24
Q

How is paludrine taken for malarial prophylaxis?

A

1 tablet daily for 1 week, during travel, and 4 weeks after travel

25
How is doxycyline taken for malarial prophylaxis?
1 tablet daily 2 days before travel, during travel, and 4 weeks after travel
26
What specific counselling point should you remember with doxycyline?
Photosensitivity
27
How is malarone taken for malarial prophylaxis?
1 tablet daily 1-2 days before travel, during travel, and 1 week after travel
28
How is mefloquine taken for malarial prophylaxis?
1 tablet weekly 2-3 weeks before travel, during travel, and 4 weeks after
29
Which specific patients should you avoid giving mefloquine to?
Epileptics Depressive patients Patients with TB This is because it can increase the risk of seizures
30
What travel advice can you give for a patient?
Vaccinations Rehydration sachets Water purification tablets Bite avoidance First aid kit
31
What group of drugs do malarial prophylactic drugs interact with?
Enzyme inducers (remember CRAPPS) Carbamazepine Rifampicin Alcohol (chronic) Phenytoin Phenobarbital St Johns wort