Population Genetics Flashcards

1
Q

Discrete Trait

A

Trait with a fixed set of possible values (Blood: A, B, AB, or O ONLY)

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2
Q

Continuous Trait

A

Trait with a range of expression values (human height)

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3
Q

Population Genetics

A

Investigates how the genotype frequencies in an offspring population are related to the genotypes in a parental population

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4
Q

Null Model

A

Expected outcome given that no environmental mechanism is acting on a population

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5
Q

Stable Equilibrium

A

System does not change and returns to original state when disturbed

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6
Q

Unstable Equilibrium

A

At equilibrium, system does not change, but any disturbance will cause change away from original state

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7
Q

Neutral Equilibrium

A

At equilibrium, state does not change, but any disturbance will cause system to move to new state and remain at that state

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8
Q

Mixed Equilibrium

A

At equilibrium, system is stable in response to one type of change, but unstable in response to a different change

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9
Q

Positive Frequency Dependent Selection

A

Fitness associated with a trait increases as the frequency of the trait increases in the population
-more common a trait is, higher fitness

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10
Q

Negative Frequency Dependent Selection

A

The fitness of a trait decreases as the frequency increases in the population

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11
Q

Mutation-Selection Balance

A

Balance between ongoing deleterious mutations and the purging effect by nation selection
-selection takes out BAD mutations

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12
Q

Assortative Mating

A

Individuals mate with other individuals of the same genotype or phenotype

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13
Q

Disassortative Mating

A

Individuals mate with other individuals of different genotypes or phenotypes

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14
Q

Self-Fertilization

A

Fertilization of own gametes (hermaphrodites; plants)

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15
Q

Inbreeding

A

Mating with a genetic relative

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16
Q

What are the HWE assumptions?

A
  1. NO natural selection
  2. Organisms mate randomly with respect to the locus being investigated
  3. NO mutation is occurring
  4. NO migration in or out of the population
  5. Large population size so genetic drift is negligible
    only ONE of these assumptions can be violated
17
Q

Compare allele frequencies between sink and source populations over time following migration

A

Allele frequencies of sink population can change over time as a result of migration of individuals from the source population (violates HWE)

18
Q

How to determine a population is in HWE?

A

HWE Equations: p+q=1 & p^2+2pq+q^2=1
-Must get genotype frequency, allele frequency, expected genotype, expected/predicted individuals
-Do chi-square analysis (critical value is 3.84; lower than CV means in HWE, above CV means NOT in HWE)

19
Q

Chi-Square Analysis?

A

x^2=E[(obs-exp)^2/exp]
Critical value is 3.84 (<3.84 means in HWE, >3.84 means NOT in HWE)