potentially malignant disorders

Question 1

potentially malignant conditions

Answer 1

erosive lichen planus
oral submucous fibrosis
iron deficiency
tertiary syphilis

Question 2

potentially malignant lesions

Answer 2

leukoplakia: commonest PML to transform
chronic hyperplastic candidosis
proliferative verrucous leukoplakia: highest malignant transformation
erythroplakia

Question 3

chronic hyperplastic candidosis

Answer 3

commisures of smokers, dysplasia may be present

Question 4

histology of CHC

Answer 4

H+E
neutrophils in epithelium
mitotic figures
dysplasia

PAS (periodic schiff stain)
show c albicans hyphae

Tx fluconazole 14 days

Question 5

dysplasia and atypia

Answer 5

dysplasia disordered maturation in a tissue
atypia changes in cells

Question 6

histological signs of dysplasia

Answer 6

pleomorphism
hyperchromatism
mitotic figures
inflammatory infiltrate

Question 7

staging of OC

Answer 7

CLINICAL
T size
N nodular involvement
M distant metastasis

Question 8

grading of OC

Answer 8

WHO 2005
hyperplasia, mild, moderate, severe, carcinoma in situ