powders and granules Flashcards

1
Q

can be taken orally

A

for internal use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

solid powders can be applied to compromised areas of the body

A

for external use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

powders are more stable than are liquid dosage forms c

A

composition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

pass through a no. 8

A

very coarse (no.8)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

pass through no. 20

A

coarse no. 20

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

pass through no. 40

A

moderately course no. 40

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

pass through no. 60

A

fine no. 60

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

pass through no. 80

A

very fine no. 80

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

typically fall within the range of 4 to 12 sieve size

A

granules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

particles are passed by mechanical shaking

A

sieving

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

use of a calibrated grid background

A

microscopy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q
  • measuring the terminal settling velocity of particles
  • may be calculated from stake’s law
A

sedimentation rate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

determined by the reduction in light reaching the sensor

A

light scattering

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

blending small amounts of powder

A

spatulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

used in small-scale preparation of ointments and suspensions

A

levigation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

two or more powdered substances are to be combined to form a uniform mixture

A

blending powders

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q
  • particle size of a solid substance to a finer state
  • increase in the specific surface area
A

comminution of drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

grinding a drug in a mortar

A

trituration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

pulsed laser is fired through an aerosolized particle spray

A

laser holography

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

passing them through sifters

A

sifting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

small amount of a potent substance is to be mixed

A

geometric dilution

18
Q

mixing powder in a rotating chamber

19
Q

some powders may become sticky or pasty or may liquefy when mixed together

20
Q

Dispense the ingredients in tight containers and incorporate a desiccant packet or capsule when necessary.

A

Hygroscopic and Deliquescent Powders

21
- Should have a uniform, small particle size that will not irritate the skin when applied.
Topical Powders
22
topical powders are consist of?
base or vehicle (cornstarch or talc) adherent (magnesium stearate, calcium stearate, or zinc stearate) active ingredient, along with an aromatic material.
23
intended to be applied in a body cavity
Insufflated Powders
24
Some medicated powders are administered by inhalation with the aid of dry powder inhalers (DPIs),
Aerosol Powders
25
device used to administer an inhalation powder
DPI
26
used with a device that aerosolizes and delivers an accurately metered amount.
inhalation powder
27
which the patient takes by mixing with water or another beverages before swallowing;
acids and laxatives
28
dissolved in warm water by the patient for vaginal use;
douche powders
29
After a powder has been properly blended (using the geometric dilution method for potent substances), it may be divided into individual dosing units based on the amount to be taken or used at a single time.
Divided Powders
29
medicated powders for external application to the skin
anti-infectives or antifungals
29
containing B-complex vitamins and other nutritional supplements.
brewer’s yeast powder
30
weigh each portion of the powder individually. This
For potent drugs
31
32
block and divide method
for non-potent drugs
33
a thin, semi-opaque paper with limited moisture resistance
vegetable parchment
33
Powders containing neither volatile components nor ingredients adversely affected by air or moisture
simple bond paper
34
a glazed, transparent paper, also with limited moisture resistance
glassine
35
a transparent waterproof paper
waxed paper
36
- a dosage form composed of dry aggregates of powder particles - are frequently compacted into tablets or filled into capsules
granules
37
granules is Derived from Latin word: which means little grain
“Granulum”
38
granules size
Usually pass in the 4 to 12 mesh size range
39
particles are placed in a conical piece of equipment
Fluid Bed Processing
39
Moisten the powder or powder mixture
Wet Method
40
preparation of granules:
wet and dry method
41
passed through a roller compactor and then through the granulating machine.
Dry Method
42
“roll press”, processes a fine powder into dense sheets .
Roll compactor