Power Points From Whatsapp

Question 1

Genus features of mycobacteria

Answer 1

Acid fast rods with waxy cell wall

Obligate aerobe

Sensitive to UV

Cell wall

Question 2

What are the features of the mycobacterium cell wall?

Answer 2

High lipid concentration, mycolic acids

Resistance to desiccation and chemicals

Question 3

What species of mycobacterium are medically important

Answer 3

Tuberculosis
Leprae
Avium intracellulare
Kansasii
Marinum
Ulcerans

Question 4

Mycobacterium tuberculosis feature that is staining Fluorescent apple green

Answer 4

Auramine rhodamine staining bacilli

Question 5

Tuberculosis is positive for

Answer 5

Acid fast bacilli

Question 6

Tuberculosis is aerobic and slow growing an

Answer 6

Löwenstein-Jensen medium

Question 7

Tuberculosis produces

Answer 7

Niacin

Question 8

What type of catalyse does tuberculosis produce

Answer 8

Heat sensitive (active at body temperature)

Question 9

Where is the reservoir of tuberculosis

Answer 9

Lungs

Question 10

Transmission of tuberculosis is through

Answer 10

Respiratory droplets

Question 11

Tuberculosis is a — intracellular organism

Answer 11

Facultative

Question 12

Tuberculosis has sulfolipids in cell envelope that inhibit

Answer 12

Phagosome - lysosome fusion

Question 13

What are the effects of cord factor of tuberculosis

Answer 13

Causes serpentine growth
Inhibits leukocyte migration which disrupts mitochondrial respiration

Question 14

Tuberculosis has a surface protein called tuberculin with mycolic acid, this causes

Answer 14

Delayed hypersensitivity and cell mediated immunity

Question 15

What are the symptoms of primary pulmonary tuberculosis

Answer 15

Fever and dry cough

Question 16

Where do the tuberculosis replicate killing them until cell mediated immunity is reached

Answer 16

Naive alveolar macrophages

Question 17

What is a ghon complex

Answer 17

Lesson seen in the lesion by tuberculosis

Question 18

What do the macrophages do in tuberculosis

Answer 18

Transport bacilli to regional lymph node

Question 19

Symptoms of reactivation TB

Answer 19

Fever, hemoptysis, night sweats. weight loss

Question 20

Erosion of granulates into airways from TB later in life under conditions of reduced + cell immunity can lead to

Answer 20

Mycobacterium replication and disease symptoms

Question 21

Reactivational TB is complex with potential of

Answer 21

Infecting any organ systems

Question 22

reactivational TB may disseminate

Answer 22

Kidney, GI tract, brain, spine

Question 23

What is pott disease

Answer 23

Dangerous musculoskeletal tuberculosis

Bone destruction, deformity and paraplegia

Question 24

In the diagnosis of TB, microscopy of sputum is done what is it screened with

Answer 24

Auramine rhodamine stain (florecent green apple)

Question 25

mycobacteria is Acid fast, ham will it appear in UV

Answer 25

Yellow or orange

Question 26

How is PPD skin test done for TB

Answer 26

purified protein derivative tuberculin is injected into inner forearm skin surface

Question 27

Positive ppd test looks like

Answer 27

Swollen reddish skin ranging from 5-15mm

Question 28

What does quantiferon TB gold test measure

Answer 28

Interferon- gamma production when leukocytes are exposed to TB antigens

Question 29

TB is slow growing on which medium

Answer 29

Löwenstein-Jensen

Question 30

TB produces _ and is negative for -

Answer 30

Niacin Does not produce catalyse

Question 31

What is the treatment for standard observed short- term therapy for uncomplicated pulmonary TB in the first 2 months

Answer 31

Ripe Rifampin Isoniazid Pyrazinamide Ethambutol

Question 32

The last 4 months of uncomplicated pulmonary TB ore treated with

Answer 32

Rifampin Isoniazid

Question 33

What is added to TB treatment in the case of possible drug resistance

Answer 33

Streptomycin

Question 34

What 3-5 previously unused drugs can be administered for multi-drug resistant TB

Answer 34

Aminoglycosides Fluroquinolones Thioamine Cycloserine Bedaquiline

Question 35

What can be done to prevent TB

Answer 35

BCG vaccine Isoniazid for nine months(infection with no symptoms) UV or hepa filter

Question 36

Non TB mycobacteria are non contagious, where can they be found

Answer 36

Surface water Soil cigarettes