pps 106

Question 1

____ by nature of its small size, allows flexibility in a protein; it is also the only _____ amino acid.

Answer 1

Glycine

non-chiral

Question 2

____ residues can produce a sharp change of direction in the amino acid _____ of a protein.

Answer 2

Proline

backbone

Question 3

____ bonds formed between _____ side chains are responsible for curly hair.

Answer 3

Disulphide

cysteine

Question 4

_____ has a similar molecular structure to Kevlar but is at least # times tougher; toughness is the ability of a material to _______

Answer 4

spider silk
10
absorb energy plastically and deform without breaking

Question 5

Spider silk, like the man-made fibre ____, contains regions of _____ protein structure, and also small ___structures.

Answer 5

Kevlar
amphorous
Beta-sheet

Question 6

____ silk consists of a repetitive _____ sequence. In the fibre, adjacent ____ are held together by ____

Answer 6

silkworm silk
alanine-glycine
beta sheets
interdigitation

Question 7

______ are all suitable anti-HIV drug targets.

Answer 7

HIV protease
HIV reverse transcriptase
HIV integrase

Question 8

The most common configuration of a peptide bond is ____

Answer 8

trans planar

Question 9

antiparallel = facing ?

Answer 9

opp directions

Question 10

>
>
<
> 
antiparallel?

Answer 10

yes

Question 11

>
<
>
<
parallel?

Answer 11

no - antiparallel

Question 12

>
>
>
>
 antiparallel?

Answer 12

no- parallel

Question 13

α-D-glucose and β-D-glucose are examples of two:

Answer 13

anomers

Question 14

what occurs in the cytosol of a eukaryotic cell?

Answer 14

glycolysis and fermentation

Question 15

Which electron carrier(s) function in the citric acid cycle?

Answer 15

NADH and FADH2

Question 16

Which of the following ETC complexes does NOT pump protons?

Answer 16

Complex II

Question 17

Starting with one molecule of glucose, the nett energy-containing products of glycolysis are:

Answer 17

2 NADH, 2 pyruvate, and 2 ATP

Question 18

What is the total number of sterioisomers possible for a carbohydrate with three chiral carbons?

Answer 18

8

Question 19

The first step in gluconeogenesis is the ____________ of pyruvate to form oxaloacetate.

Answer 19

carboxylation

Question 20

What is the primary gluconeogenic organ in animals?

Answer 20

liver

Question 21

example of a disaccharide?

Answer 21

sucrose

Question 22

The primary role of oxygen in cellular respiration is to:

Answer 22

act as an acceptor for electrons and hydrogen, forming water.

Question 23

α-D-glucose and β-D-glucose are examples of TWO:

disaccharides.
polysaccharides.
enantiomers.
anomers.

Answer 23

anomers

Question 24

_____ are separately folded regions of the same protein.
Large proteins with domain structures are ____ because it is ____ for a ____ sequence to fold up all in one go into a _____.

Answer 24

domains
common
not efficient
long protein 
single large domain

Question 25

An enzyme speeds up a chemical reaction by:

Answer 25

decreasing the activation energy.

Question 26

Following the anaerobic degradation of ONE glucose molecule by glycolysis and the TCA cycle only, the net yield of ATP molecules is:

Answer 26

four

Question 27

For a case of simple enzyme inhibition, the binding of a competitive inhibitor occurs at:

Answer 27

he active site and changes Km.

Question 28

For an allosteric or co-operative enzyme the Hill coefficient: None of the other options are correct. is equal to the number of protein subunits. is always greater than the number of binding sites. is equal to the number of active sites.

Answer 28

None of the other options are correct.

Question 29

For an enzyme which normally has a coenzyme attached to it for catalytic activity, the protein alone is known as the:

Answer 29

apo-enzyme

Question 30

For a simple enzyme catalysed reaction the Km value is:

Answer 30

the equilibrium constant for the binding of enzyme to substrate.

Question 31

For a simple enzyme catalysed reaction the substrate concentration dependence is:

Answer 31

hyperbolic

Question 32

Fructose-1,6-bisphosphate stimulates the activity of which enzyme?

Answer 32

pyruvate kinase

Question 33

Futile cycles are avoided in glycolysis and gluconeogenesis because these pathways:

Answer 33

have key metabolic steps that use different enzymes.

Question 34

Gluconeogenesis from lactate requires the activity of:

Answer 34

aldolase

Question 35

Glycogen is a:

Answer 35

polymer of α-glucose monomers.

Question 36

Glyceraldehyde-3-phosphate dehydrogenase:

Answer 36

uses inorganic phosphate.