pracs Flashcards

(41 cards)

1
Q

How are metabolic reactions controlled by enzymes

A

Enzymes combine with the substrate molecule at the active site to produce a product

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2
Q

Structure of enzymes

A

Tertiary proteins where the polypeptide chain is folded back on itself into a spherical 3D globular shape

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3
Q

What are enzymes

A

Biological catalysts which speed up the rate of metabolic reactions

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4
Q

What is digestion

A

Large food molecules are digested by enzymes into smaller molecules and these products are then absorbed to the bloodstream

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5
Q

What is the active site

A

Where the substrate attaches to on the enzyme (groove in the enzyme)

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6
Q

What is a substrate?

A

Molecule that the enzyme breaks down into products

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7
Q

What is the lock and key theory

A

Enzymes are specific so the substrate is perfectly complementary to the active site

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8
Q

What enzyme is protein broken down by

A

Proteases

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9
Q

Where is protease found

A

Stomach, pancreas, small intestine.

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10
Q

What are proteins

A

Long chains of chemicals called amino acids

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11
Q

What happens when we digest proteins

A

The protease enzymes convert the protein back to the individual amino acids, which are then absorbed into the bloodstream

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12
Q

How are human proteins made

A

When amino acids are absorbed by the body cells they are joined together in a different order to make human proteins

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13
Q

Structure of the carbohydrate starch

A

Consists of a chain of glucose molecules

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14
Q

What are carbohydrates broken down by?

A

Carbohydrases

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15
Q

What carbohydrase breaks down starch

A

Amylase

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16
Q

What happens when carbohydrates like starch are digested

A

We produce simple sugars

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17
Q

Where is amylase found

A

In the saliva and pancreatic fluid

18
Q

Structure of lipid

A

Molecule of glycerol attached to 3 molecules of fatty acids

19
Q

What enzyme digests lipid molecules? And what does it produce

A

Lipase. Produces glycerol and fatty acids

20
Q

Where is lipase found

A

Pancreatic fluid and small intestine

21
Q

What else is involved in the digestion of lipids

22
Q

Where is bile made and stored

A

Made in liver, stored in gall bladder

23
Q

What does bile do

A

Speeds up the digestion of lipids but is not an enzyme

24
Q

How does bile work

A

Converts large lipid droplets into smaller droplets (emulsifies the lipid) which increases S.A of lipid droplets and increases rate of lipid breakdown by lipase.

25
Why do we need to break down the biological molecules we eat (carbohydrates, proteins, lipids)
Normally pretty big molecules so too big to absorbed into bloodstream across villi of small intestine, so broken down to smaller pieces by enzymes
25
What does bile do to the small intestine
Creates alkaline conditions because it is alkaline so can neutralise stomach acid.
26
What is activation energy
Minimum energy needed to start a chemical reaction/energy needed to break existing chemical bonds
27
What do enzymes do to activation energy
Lower the activation energy of a reaction
28
Factors effecting rate of enzyme action
Temperature, pH, substrate concentration, enzyme concentration
29
What do buffers do
Maintain a constant pH
30
What are enzyme inhibitors
Inhibitor combines with enzyme and stops it from forming enzyme-substrate complex.
31
What are competitive inhibitors
Structurally similar to the substrate molecule so it can fit into active site instead of substrate
32
What are non-competitive inhibitors
Don't bind to active site. Bind to allosteric site of enzyme and alters the overall tertiary structure of the enzyme molecule.
33
Function of small intestine in digestion
Digestion and absorption
34
Two regions of the small intestine
The duodenum and the ileum
35
How is the ileum adapted for absorption in humans
- Very long and lining folded to give large S.A. - Folds have villi and on surface of villi are epithelial cells with microvilli. Increase S.A - At base of villi are glands called crypts of Lieberkuhn and the epithelial cells of the crypts produce digestive enzymes which complete digestion.
36
Why do epithelial cells contain mitochondria
As ATP is needed for the active absorption of some of the products of digestion by active transport
37
Purpose of goblet cell in intestine
Produce mucus
38
Two features of columnar epithelium
- Mitochondria to produce ATP for active transport to help with digestion. - Microvilli to increase S.A for diffusion. More space for molecules to diffuse in and out.
39
Why is the small intestine of a herbivore (rabbit) longer
Because herbivores have difficulty digesting cellulose so food takes longer to travel down the gut allowing more time for cellulose digestion.
40
Why is small intestine of a carnivore (cat) shorter
As protein is easy to digest.