Practice questions Flashcards

(46 cards)

1
Q

A drug interaction that occurs when the combined effect of 2 drugs taken together decreases the effect of the drugs individually

A

Antagonism

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2
Q

What drugs can cause interaction with Warfarin

A

Aspirin, antibiotics or tylenol (acetaminophen)= increased bleeding

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3
Q

examples of Calcium channel blocker

A
  • Diltiazem (Tiazac)

- pine

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4
Q

what is the greatest danger of taking OTC antacids?

A

Can affect the absorption of other drugs

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5
Q

Drug-disease interaction of aspirin

A

salicylates- in toothpaste, food preservatives
nasal polyps
causes asthmatic attacks or diff breathing

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6
Q

side effects of opioids

A

constipation

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7
Q

What drugs make up the the “triple whammy”

A

ACE Inhibitors + diuretics + NSAIDS
ACE inhibitors- pril
Can cause renal impairment when taken together

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8
Q

Drug-drug interactions

A

Diltiazem & erythromycin

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9
Q

side effects of furosemide

A

hyperglycemia, hypotension, allergic reaction

-reduces fluid retention (edema)

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10
Q

Examples of adverse drug reaction

A

idiosyncrasy= eg- allergy to air
Teratogenic effect= birth defects
anaphylaxis= life-threatening allergic reaction

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11
Q

Brand name and S/E of Trazadone

A

Desyrel

S/E= drowsiness

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12
Q

Effects of opioid analgesics like codeine etc

A

lower HR and respiration

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13
Q

What is digitalis

A

used to strengthen the contractions of the heart muscle

Overdose= GI disturbance, cardiac arrhythmia, blurred vision

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14
Q

S/E of antiprotozoal drugs (malarial drugs)

A

vivid dreams, abdominal pain, HA, N/V, hypotension, visual disturbance, insomnia

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15
Q

S/E of Olanzapine (Zyprexa)

A

Antipsychotic; schizophrenia & bipolar disorder

S/E: orthostatic hypertension, syncope related to low BP, weight gain, neuroleptic sensitivity, Parkinsonism

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16
Q

Generic of Xanax

A

Alprazolam
Schedule IV
Benzodiazepine; GABA

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17
Q

Beta II Agonist drugs

A

-Albuterol

used for COPD

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18
Q

examples of NSAIDs

A

ibuprofen, celecoxib (Celebrex), aspirin, naproxen, nabumetone, meloxicam, etodolac, diclofenac, indomethacin

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19
Q

Drug class for antibiotics, antivirals, antifungals

A

anti-infective

20
Q

Which drug class has the suffix -olol

A

Beta Blockers
Cardiovascular
Eg: metoprolol (Lopressor & Toprol XL) , Atenolol (Tenormin)

21
Q

The generic name for Cefzil?

A

Cephalosporin- antibiotics

22
Q

Schedule IV controlled substances

A

Sleep aids + benzodiapines

  1. Ativan (Lorazapem)
  2. Ultram (Tramadol)
  3. Restoril ( Temazepam)
  4. Soma (Carisprodol)
  5. Ambien (zolpidem )
  6. Xanax (Alprazolam)
  7. Lunesta ( eszopiclone)
  8. valium ( diazepam)
  9. Librium ( Chlordiazepoxide)
  10. Klonopin (Clonazepam)
23
Q

How many refills within what time period can be authorized for schedule IV drug?

A

5 refills within a 6-month period

24
Q

How many refills can be authorized for a schedule II drug

25
Schedule II controlled drugs
``` Oxycodone (Roxicodone) Adderall Opium Vicodin (Hydrocodone/ acetaminophen) Percocet ( Oxycodone/ Acetaminophen) Vyvanse ( Lisdexamfetamine) Cocaine Morphine Demerol (Meperidine) Concerta ( methylphenidate) ```
26
Which government branch is responsible for assigning schedules of controlled substances
US Attorney General
27
Do pharmacists hired by hospitals/institutions need to register to handle controlled substances
No
28
What are the constituents of Allegra-D
Fexofenadine HCl & Pseudoephedrine HCl
29
ROMAN NUMERALS
M- 1000 C- 100 L- 50 D- 500
30
Joint Commission
accredits health care institutions based on pt care & safety standards
31
Safety Data Sheets (SDS)
Details chemical products, potential dangers assx with these chemicals & measures taken in case of exposure
32
Occupational Safety and Health Administration (OSHA)
Ensures a safe and healthy workplace
33
In a horizontal flow hood, how far should one work inside the hood?
6 inches
34
what can the direct mixture of calcium gluconate and potassium phosphate soln for injection cause
precipitate
35
Lactated Ringer's solution
contains Na, Ca, K salts | Used for IV irrigation
36
what ingredient in TPN may interact with Warfarin
Vit K- renders it ineffective
37
Herbal preparation used for depression and possible immune system benefits
St John's wort | Not approved by FDA
38
functions of physicians regarding the use of investigational drugs
1. obtain approval from the IRB 2. explain drug benefits & risks to pt and obtained a signed consent 3. send a copy of consent form to pharmacy Pharmacies -stores and dispenses the drug
39
Schedule III controlled drugs
1. Vicoprofen- oxycodone/ibuprofen | 2. Fiorinal- Butalbital, aspirin & caffeine
40
Drug-Anecdote
Acetaminophen- N-acetylcysteine warfarin- Vit K Anthracycline chemotherapy- Dexrazoxane Benzo- Flumazenil
41
What % of dextrose and sodium chloride are in a liter of D5NS?
5% dextrose; 0.9% NS
42
Egs of antifungal agents
Fluconazole, Nystatin
43
What is a misbranded drug?
Has untrue or incorrect claims or labeling like labeling that does not have appropriate instructions for use or warning specific to the drug
44
X'tics of filling a C-II drug
1. Can be partially filled if the remainder is available within 72 hours 2. Emergency fill is allowed; Dr must provide the pharmacy with a hard copy within 7 days 3. Can be hard or soft copy but needs to be signed by a Dr
45
Drugs that cannot be delivered via the pneumatic tube system
1. Gemcitabine (chemo drug) 2. Pegfilgrastim ( proteins can denature) 3. Abciximab (denatured)
46
Constituents of various insulins
1. Lantus- Insulin glargine 2. Novolog- Insulin aspart 3. Humalog (Apidra)- Insulin lisper 4. Levemir- Insulin detemir