Pre-Clinical Pharm Flashcards
(31 cards)
Propofol
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
Diprivan
1.5-2.5 mg/kg adult
2.5-3.5 mg/kg peds
Decrease dose in elderly
PONV 10mg
Itching 10-15mg
Sedation 25-100 mcg/kg
TIVA 100-300 mcg/kg/min
GABAa agonist
3-5 minutes
Burns when injected
Decreases BP, SVR, CO. Cardiac sensitive. Bradycardia. Hypercapnia
Allergy. Hypoventilation. Apnea. Loss of airway reflexes. Myoclonus
Rocuronium
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
Zemuron
0.6-1.2 mg/kg
Non depolarizing paralytic
Redose with 0.1mg/kg
Duration of 20-35 minutes
Does release histamine
Succ
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
Anectine
-0.5-1 mg/kg
-Duration of 3-5 minutes
-Depolarizing Muscle Relaxant
-2 acetylcholine molecules bound together which attach to alpha subunits of nicotinic acetylcholine receptors and mimics depolarization.
-Releases Histamine
-increase K by 0.5mEq
-bradycardia from SA node action
-enhanced with anticholinesterase
-reversed with anticholinesterase
-upregulation of extrajunctional receptors
-increased intragastric pressure but also increase in LES pressure
-Dibucaine tests detects atpycal cholinesterase enzyme not the number
-slight increase in ICP
Vecuronium
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
Norcuron
-non depolarizing parlaytic
-0.1 mg/kg
-duration of 20-35 minutes
-renal(20%) and liver excretion (80%)
-NO histamine release
-woman more sensitive than men
Cisatracurium
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
Etomidate
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
Lidocaine
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
Bupivicaine
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
Ropivicaine
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
LTA Kit
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
Midazolam
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
Fentanyl
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
Neostigmine
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
Glycopyrolate
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
Sugammadex
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
Dexmedetomidine
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
Ketamine
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
Atropine
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
Phenylephrine
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
Ephedrine
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
Vasopressin
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
Famatodine
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
Norepinephrine
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
Clevidipine
Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts
