Pre-eclampsia Flashcards
What is gestational hypertension / pregnancy induced hypertension
New hypertension >20 weeks with no proteinuria
What is pre-eclampsia
Multisystem disorder characterised by hypertension >20 weeks and proteinuria
What is eclampsia
Seizure or convulsive episode caused by PET
High risk factors for pre-eclampsia
Hypertension previously in pregnancy
Chronic renal or autoimmune disease
Diabetes
Chronic HTN
Moderate risk factors for pre-eclampsia
First pregnancy
Aged over 40
BMI >35
FHx of pre-eclampsia
Multiple pregnancies
What is given as prophylaxis if there are risk factors
Aspirin 150mg once a day for 12 weeks until delivery
Complications of hypertension
Maternal death
Intracranial haemorrhage
Acute fatty liver of pregnancy
Eclamptic seizures
Hepatic necrosis / rupture
Pulmonary oedema
HTN in later life
CV disease, CVA, IHD
IUGR
Stillbirth
Prematurity - iatrogenic early birth major cause
Symptoms of pre-eclampsia
Headache
Visual disturbances
Nausea
Abdominal pain
Feeling unwell
Reduced fetal movements
Examinations in pre-eclampsia patients
BP
Abdominal palpation tenderness
Obstetric assessment
Investigations in pre-eclampsia
BP monitoring
Urinalysis for proteinuria and PCR
LFTs, FBCs, urea and electrolytes
Fetal assessment - CTG and US
Treatment options to protect mother
HTN complication monitoring
PET complication monitoring
What is used to treat eclampsia
IV Mg sulfate - given as 4g IV bolus then 1g/hr infusion. Monitoring required
Treatment to protect baby in eclampsia
prolong gestation when safe, but give steroids IM
Drug sto control hypertension in pregnancy
Labetalol, Nifedipine, Methyldopa
Management of pre-eclampsia / eclampsia
Stabilise then deliver the baby if needed
