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HEMATOLOGY 1 > PRE LIM COVERAGE HEMA1 > Flashcards

PRE LIM COVERAGE HEMA1 Flashcards

1
Q

liters of blood in the body

A

5 liters/ 5,000 ml

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2
Q

functions of blood

A

blood transport, clears tissues, trans
port, moves wastes

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3
Q

the liquid portion of blood is called as

A

plasma/ components (provides coagulation enzymes)

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4
Q

3 categories of blood cell

A

RBC or erythrocytes, WBC or leukocytes, platelets or thrombocytes

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5
Q

hematology and all

A

study of blood in health and in pathologic condition/ haima blood and logos study of

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6
Q

eccentricity

A

measures how much cell deviates from being central (sickle shape)

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7
Q

athanasius kircher

anton van leeuwenhoek

guilio bizzozero

james homer wright

paul herlich

william hewson

A

described worms in the blood

father of microbiology

described platelets

stain

classified leukocytes

father of hematology

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8
Q

Morphology

A

cell appearance such as color, size,

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9
Q

Megakaryocyte

A

origin of platelets

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10
Q

Thrombopoiesis

A

generation of
megakaryocytes shedding into
thousands of platelets.

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11
Q
A
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12
Q

FUNCTIONS OF BLOOD

A
  • Respiration/ transport - Nutrition
  • Excretion
  • Homeostasis (the normal balance of your
    body)and Body Protection
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13
Q

CHARACTERISTICS OF BLOOD

A

Fluid in vivo (in the body

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14
Q

Slightly alkaline

A

[pH 7.35- 7.45]

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15
Q

Specific Gravity

A

[1.045- 1.065]

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16
Q

COMPOSITIONOF BLOOD

A

liquid and solid

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17
Q

COMPOSITIONOF BLOOD ( liquid)

A

Plasma,Serum

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18
Q

COMPOSITIONOF BLOOD ( solid)

A

rbc,wbc,granulocytes,agranulocytes

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19
Q

rbc, wbc, platelets normal values

A

3.8 – 6.0 x10^12/L (M/mL) – normal values
3.6-10.6 X 10^9 L (T/mL)- normal values
150-450 X 10^9/L (T/ML)- normal values

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20
Q

Granulocytes

A

BEN

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21
Q

Agranulocytes

A

LM

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22
Q

IDENTIFY THE TYPE OF WBC

A

benlm

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23
Q

PRIMARY SERVICES OFFERED BY
HEMATOLOGY AND HEMOSTASIS LAB

A

Specimen collection and preparation for
examination
- Quantitative manual and instrumental
measurements of cells
- Measurements of cell volumes
- Evaluation of cellular contents and
components
- Cellular identification
- Identification of reactive or neoplastic [can
be cancerous] alterations of cell populations
- Evaluation of leukocytes, erythrocytes and
platelet function
- Evaluation of cellular development and
formation (Bone Marrow)
- Evaluation of the hemostatic function

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24
Q

Occupational Safety and Health Administration (OSHA)

A

1996 – Standard Precautions is now used – encompasses UP (Universal Precautions) and BSI (Body
Substance Isolation)

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25
Potentially Infectious Materials
- Blood, Semen, All Body Fluids (Identified or Unidentified), Microhematocrit Clay, Unfixed Slides
26
Occupational Hazards
Biological, Fire, Chemical, Electrical, Mechanical
27
BIOLOGICAL HAZARDS
Regardless of source, all body fluids are considered infectious and biohazard
28
OSHA Standards
Handwashing - Personal Protective Clothing and Equipment - Decontamination of work surfaces, equipment and spills
29
FIRE HAZARDS
Improper use or storage of cryogenic
30
3 levels of control
accuracy, precession, delta cheeks
31
linearity
closenes to the true actual value
32
reliability
closeness of the result that abstained repeated analysis
33
reference interval
ranges of values of analyte to a healthy individuals
34
diagnostic sensitivity
proportion pxs w/ disease with a positive result
35
diagnostic specificity
proportion pxs identified correctly by the test w/o disease
36
systematic error
errors within test system or method
37
CHEMICAL HAZARDS
Occupational exposure to hazardous chemicals in the laboratory
38
Degree of Hazard:
4 – Extreme Hazard 3 – Serious Hazard 2 – Moderate Hazard 1 – Slight Hazard 0 – No/Minimal Hazard
39
ELECTRICAL HAZARDS
- Electrical shock, burns, fire, or explosion
40
MECHANICAL HAZARDS
Improper use, storage, or disposal of glassware, sharp instruments, compressed gases, or equipment
41
PREANALYTICAL ERRORS
- Specimen obtain from patient - Specimen procured at the wrong time - Specimen collected in the wrong tube - Blood specimen collected in the wrong order - Incorrect labelling - Improper processing of specimen
42
ANALYTICAL ERRORS
- Oversight of flagging - Out of control Quality Control results - Wrong assay performed
43
POSTANALYTICAL ERRORS
Verbal of reporting the results lab info system incompatibility error confusion of ref ranges failure to report critical values ASAP
44
INTERNAL QUALITY CONTROL
actual running of control by the staff (internal to the lab) est. a new ref interval (no existing analyte or methodology) verifying a ref interval (transference)
45
external quality control
neqas- national external quality assessment scheme
46
quality control
procedure evaluate and monitor cxs of testing system accurate and precision
47
NFPA diamond hazard symbols
yellow instability h red fire or flashpoint h blue health h white special h
48
QUALITY ASSURANCE
- Coordinate effort to organize laboratory activities - Provide best service to patient and doctor Control and Monitor: - Staff competence - Material, methods (SOP – Standard Operating Procedure Manual – needs to be updated) - Reporting of results - Patient and doctor satisfaction - Financial costs
49
CONTROL
- Same matrix as patient sample - Predetermined assay value (Normal, Low, High)
50
PRIMARY STANDARD
Calibrate instrument - Fixed and known composition
51
SECONDARY STANDARD
Analyte concentration ascertained by reference to a 1* standard
52
CALIBRATOR
- Preserved human or surrogate cell suspension - Determined hemorrhagic parameters
53
cbc
- Foundation procedures - Disorders - Abnormalities in RBCs, WBCs, and Platelets
54
cbc test
A. Hemoglobin B. Hematocrit C. Red Blood Cell Count with Morphology D. White Blood Cell Count with Differential Count E. Platelet Estimate F. Red Blood Cell Indices
55
Techniques in Performing Complete Blood Count:
disadvantages and advantages
56
HEMOGLOBIN
estimated by: (3) decting and assesing: (1) principle/ gold standard:(2) manual reagent: drabkins solution:
57
HEMOGLOBIN ref values
ad,af,i,nb
58
HEMATOCRIT
Method Measured reference method calculation:
59
HEMATOCRIT ref values
m,f
60
RED CELL INDICES
Morphologic classification used calculated
61
3 indices
mcv,mch,mchc
62
mcv,mch,mchc
fermtoliter,pictogram,g/dl
63
LEUKOCYTE DIFFERENTIAL COUNT
Relative (Percentages) Multiply the relative number of WBCs by the Total WBC count per L
64
RETICULOCYTE COUNT
Juvenile Red Blood Cells manual stain: relative count: absolute count:
65
ERYTHROCYTE SEDIMENTATION RATE (ESR)
Measure of degree of settling of RBC in plasma 2 Methods: test normal values
66
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HEMATOLOGY 1 (3 decks)

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