Preanesthetics Flashcards
(15 cards)
What is the drug class that we use as preanesthetics?
Anticholinergics
What is another name for this class?
Parasympatholytics
What are the main two drugs in this class?
- Atropine Sulfate
- Glycopyrrolate
What is the dose and concentration of Atropine?
Dose - 0.02 mg/lb
Strength - 0.54 mg/mL
What is the dose of Glycopyrrolate?
Dose - 0.005 mg/lb
Which of the drugs in this class does not cross the blood-brain/placental barrier?
Glycopyrrolate
How long does each of the drugs in this class last?
Atropine –> 90 min (1.5 hr)
Glyco –> 2-4 hr
Which of these drugs are more expensive?
Glycopyrrolate
What are the two main reasons for using this class of drug?
- Decrease in saliva production
- Prevent bradycardia
This class is used to prevent bradycardia, which is caused by what?
Intubation stimulates the vagal nerve which induces a PSNS response which slows the heart
What are some other neutral effects of this class of drugs?
- Dilated pupils
- Decreased tear production
Why is this class not given to horses and ruminants?
- Drug reduces gut motility which can cause ruminal atony (bloat) and colic (ileus)
What are the harmful side effects of this class and what can these effects lead to?
- Decreased gut motility - bloat and colic
- Bronchodilation - increases dead space
- Initial bradycardia when adm IV
- Cardiac arrhythmias
- CNS depression (in dogs and cats) - only w/ atropine
- CNS excitement (in ruminants) - w/ atropine
What are the contraindications for this class of drugs?
- Preexisting tachycardia
- Heart disease
- Constipation/ileus
What bpm is tachycardia for dogs and cats?
- Dog = >140
- Cat = >160
