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SDNP exam > Precancer/nonmelanoma skin cancers > Flashcards

Precancer/nonmelanoma skin cancers Flashcards

1
Q

Atrophic flat pearly pink to red thin, scaly plaque

A

superficial BCC

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2
Q

speckled brown, blue, black melanin in lesions

A

pigmented bcc

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3
Q

atrophic poorly defined borders, smooth pink or flesh colored papules/plaques, may have a scar appearance

A

morpheaform/infiltrative bcc

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4
Q

Multiple BCC in childhood associated with pitted palms and soles, cysts on jaw, coarse facial features and skeletal abnormalities

A

nevoid basal cell syndrome

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5
Q

arborizing vessels
leaf like structures
concentric spoke wheel like structures
large blue gray ovoid nest
multiple blue-gray non-aggregated globules

A

BCC dermoscopy

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6
Q

High risk BCC AREA

A

THE ‘H’ AREA;
central face, periorbital, eyebrows, eyelids, nose, lips, chin, mandible, temple, ear, pre- and post-auricular, genitalia, hands, feet

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7
Q

Moderate risk BCC

A

scalp forehead, cheeks, neck, pretibial

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8
Q

low risk bcc

A

trunk/extremities

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9
Q

Low risk vs high risk BCC types

A

low risk; nodular & superficial

High risk- morpheaform, micronodular, infiltrative, basosquamous w/ perineural invasion >6mm in high risk areas or > 1 cm in low risk areas

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10
Q

1st line treatment of BCC

A

MOHs with 4 mm margin
surgical excision with 4mm margin
C&E for superficial BCC

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11
Q

precursors to SCC
cellular mutation from cumulative UV exposure
pink/red rough macules w/ a sandpaper texture, white to yellow scale occurring on sun damaged skin

A

Actinic keratosis

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12
Q

Types of 5FU cream

A
  • efudex 5% cream 2x/day for 2-4 weeks
  • tolak 4 % daily for 4 wks for lesions on face, ear, or scalp
  • carac 0.5 daily for up to 4 weeks for face and anterior scalp
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13
Q

Bowen’s disease
induced by HPV
solitary, red brown, violaceous papules/plaques that are well defined.

A

Squamous Cell in Situ

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14
Q

SCCis of glans and prepuce of penis, vulva, oral mucosa
Well defined shiny red plaque

A

erythroplasia of Queyrat

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15
Q

Sudden onset (weeks) rapidly growing plaque/nodule with crater like center of keratin

A

Keratocanthoma

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16
Q

2nd most common type of skin cancer

A

SCC

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17
Q

mutation of p53 tumor suppression gene secondary to uv exposure, aging, smoking, or immune suppression

Neural or vacular invasion may occur.

A

SCC

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18
Q

What are risk factors for SCC

A

fair, blue eyes w/ blonde or red hair
cumulative sun exposure, especially in childhood, arsenic exposure
smoking
outdoor occupation
areas of burns, trauma or chronic inflammation

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19
Q

flesh colored to erythematous papuels/nodules which may be hyperkeratotic, smooth, or ulcerated.

A

SCC

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20
Q

linear, irregular vessels
elongated hair pin vessels, dotted vessels or a combo

White halo surrounds the vessels

brown or gray dots in a linear arrangement

A

dermoscopy of SCC

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21
Q

SCC; greater than or equal to 2 cm on trunk or extremities

A

high risk SCC tumor

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22
Q

SCC; greater than 1 cm on cheeks forehead scalp neck and pretibial

A

high risk

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23
Q

SCC; less than 1cm on cheeks forehead scalp neck and pretibial

A

low risk

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24
Q

SCC; less than 2 cm on trunk and extremities

A

low risk

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25
Q

SCC; well to moderately differentiated

A

low risk

26
Q

SCC; poorly differentiated

A

high risk

27
Q

Low risk SCC management-

A

standard excision iwth 4-6mm margin or C&E for small, low risk SCC

28
Q

High risk SCC management-

A

MMS or surgical excision with confirmed negative margins

29
Q

Always check for what when performing a biopsy of a high risk SCC

A

lymph nodes

30
Q

Rare, aggressive cutaneous malignancy
>70 years old
fair skin
fast growing

A

merkel cell ca

31
Q

asymptomatic, firm, nontender, solitary, rapidly growing nodule form 0.5-5cm, may be red, pink, violaceous reddish-brown or skin colored , mostly occur in head and neck region, if lymphadenopathy present-advanced disease present.

A

merkel cell ca

32
Q

what should be ordered once merkel cell ca is confirmed with biopsy?

A

PET/CT before surgery
SNLB

33
Q

one or multiple smooth red/pink papules/plaques/nodules
slow growing

A

CBCL

34
Q

often large >5cm nonspecific eczematous dermatitis favoring lower trunk and extremities, pruritic, usually lasts for years

A

patch stage of mycosis fungoides

35
Q

well defined, dusky violaceous red collor, sometimes annular

What phase of mycosis fungoides?

A

plaque stage

36
Q

red and dusky nodules that may progress to deep ulcers, commonly occur around head, neck, groin, breasts and axillary, more aggressive form

A

Mycosis fungoides tumor stage

37
Q

erythrodermic skin, exfoliative, patient will complain of hot, painful, pruritic skin, hyperkeratosis of palmos and soles, alopecia, onychodystrophy w/ diffuse lymphadenopathy

A

sezary syndrome

38
Q

rare slow growing primary cutaneous malignancy, higher incidence in african americans, and females, mean onset 4th decade of life.

one or more multiple ill defined slow growind red brown firm plaque or nodules, typically painless

Often present in the shoulder or chest area

A

Dermatofibrosarcoma protuberans

39
Q

onset or develop at birth through age 2 years

A

congenital nevus

40
Q

How to predict adult size of CMN?

A

measure largest diameter in mm of lesion on child, then multiply:
Face- 2.8
trunk and extremities- 8
legs- 12

41
Q

Patient has LG CMN >40cm
multiple satellite nevi
more than 2 CMN
Crossing over spinal column

A

Neurocutaneous Melanosis

Refer to pediatric neurologist

42
Q

Light brown patch with hyperpigmented speckles of macules

A

nevus spilus

43
Q

onset usually adolescence, shoulders scapula and upper trunk, hair

A

becker’s nevus

44
Q

most occur between 10-20 years old

less than 10mm, symmetrical pink to red, smooth, dome shaped papule

well defined lesion on the head and lower extremities, few on trunk

A

spitz nevus

45
Q

age of onset after 10
location on the back
>1 cm
asymmetry
irregular/poorly defined borders
ulcerated/irregular surgace

A

clinical features of an atypical spitz nevus

46
Q

what is the management for a spitz nevus?

A

complete excision in both children and adults

47
Q

Severely dysplastic Nevi management:

A

completely excised with a 5 mm margin

48
Q

What is the most common type of melanoma

A

superificial spreading

49
Q

What are the ABCDEs of melanoma

A

asymmetry
border irregularity
color variegation
diameter > 6mm
evolution

50
Q

2nd most common type of melanoma
brown or black, rapidly growing lesion

A

nodular melanoma

51
Q

sun exposed skin like the face, neck and arms, irregular, flat, variegated pigmentation

A

Lentigo maligna

52
Q

Most commonly found in darker skin types
hutchinsons sign is key factor in dx suspicion

A

Acral Melanoma

53
Q

red or pink papule that enlarges and may have some grey at the periphery, RED, RAISED and RECENT CHANGE

A

amelanotic melanoma

54
Q

guidelines for in situ

A

0.5-1 cm

55
Q

guidelines for melanoma less than or equal to 1 mm

A

1cm margin

56
Q

guidelines for melanoma 1-2 mm

A

1-2cm

57
Q

guidelines for melanoma > than 2 mm to 4 mm

A

2 cm

58
Q

guidelines ofr melanoma greater than 4 mm

A

2 cm

59
Q

what are the two types of staging for the depth of a melanoma

A

breslow and clark

60
Q
A

SDNP exam (14 decks)

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