Pregnancy Changes Flashcards

1
Q

A blue/purple cervix and vagina

A

Chadwick’s sign (progesterone vasodilation increases vascularity).

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2
Q

Blotchy pigmentation of the face

A

Chloasma

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3
Q

Changes in arterial blood pressure (first 20 weeks)

A

decrease (progesterone is a smooth muscle relaxant).

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4
Q

Changes in arterial blood pressure (after 20 weeks)

A

increase (but still ends up being less than normal)

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5
Q

Plasma volume changes

A

increases 50% (makes sense, mom loses blood during delivery, so she should prepare!)

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6
Q

Systemic Vascular Resistance changes/Oncotic pressure changes

A

decrease (progesterone)/decrease (low albumin).

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7
Q

Cardiac output changes

A

increase (HR and SV-from increased plasma volume-both go up).

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8
Q

Cardiac output changes with being supine

A

decrease (uterus compresses the IVC).

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9
Q

RBC mass changes

A

increase by 30% (O2 carrying capacity goes up).

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10
Q

Hgb/Hct changes

A

decrease (remember that Hgb is a mass/volume ratio-plasma volume goes up more than RBC mass).

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11
Q

Levels of coagulation factors

A

increase (pregnancy is a hypercoagulable state).

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12
Q

Gastric motility/gastric emptying time

A

decrease/increase (predisposes to heartburn from reflux of gastric contents).

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13
Q

Colonic motility/colonic transit time

A

decrease/increase-again all from progesterone mediated smooth muscle relaxation

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14
Q

Effects of gastric motility/colonic motility changes

A

gastric reflux (heartburn)/constipation.

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15
Q

Acid base imbalance/Tidal volume change

A

respiratory alkalosis secondary to hyperventilation (TV increases).

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16
Q

Ureteral size changes

A

increase (from progesterone vasodilation), causes urinary stasis, increased UTI risk.

17
Q

Changes in serum BUN/Cr/GFR/Creatinine Clearance-

A

decrease/decrease/increase/increase.

18
Q

Glucose and Protein levels in the urine-

A

increase (glucose transport maximum goes down in the PCT).

19
Q

Pituitary size changes/possible sequelae of this change

A

increase (producing more hormones)/Sheehan’s Syndrome.

20
Q

Thyroid size change/TBG change/Total Thyroid hormone levels/Free thyroid hormone-

A

first 3 increase/last is unchanged

21
Q

B-HCG levels

A

increase for first 10 weeks, then decrease, more HCG = more vomiting (hyperemesis gravidarum).