Prelim Flashcards
(91 cards)
FERTILIZATION
process by which sperm and ovum – the male and female
gametes, or sex cells – combine to create
a single cell called a zygote.
zygote
combine to create
a single cell called
Dizygotic Twins
Fraternal twins
• the result of two separate eggs being
fertilized by two different sperm to form
two unique individuals.
• Tend to run in families and are the result of
multiple eggs being released at one time.
Monozygotic Twins
Identical Twins
• Result from the cleaving of one fertilized
egg and are generally, identical.
• They can still differ outwardly.
Mitosis
• Process by which the non-sex cells divide
in half over and over again.
• The DNA replicates itself, so that each
newly formed cells has the same DNA
structures as all the others
Mutation
Permanent alterations in genes or
chromosomes that may produce harmful
characteristics.
SEX CHROMOSOMES
23rd pair of
chromosome; one from the father and one
from the mother.
– Are either X or Y chromosomes
– X – Female
– Y - Male
ALLELES
Genes that can produce
alternative expressions of a characteristic.
– Two or more alternative forms of a gene that
occupy the same position on paired
chromosomes and affect the same trait.
HOMOZYGOUS
possessing two
identical alleles for a trait
HETEROZYGOUS
possessing differing alleles for a trait.
Dominant Inheritance
Pattern of inheritance in which, when a child receives different alleles, only the dominant one is expressed
Recessive Inheritance
Pattern of inheritance in which a child receives identical recessive alleles, resulting in expression of a
nondominant trait.
Polygenic Inheritance
Pattern of inheritance in which multiple genes at different sites on chromosomes affect a complex trait.
ALPHA1 ANTITRYPSIN
DEFICIENCY
• Enzyme deficiency that can lead to
cirrhosis of the liver in early infancy and
emphysema and degenerative lung
disease in middle age.
Alpha thalassemia
Severe anemia that reduces ability of the
blood to carry oxygen; nearly all affected
infants are stillborn or die soon after birth
Beta thalassemia (Cooley’s
Anemia)
• Severe anemia resulting in weakness,
fatigue, and frequent illness; usually fatal
in adolescence or young adulthood.
Cystic Fibrosis
• Overproduction of mucus, which collects in
the lung and digestive tract; children do
not grow normally and usually do not live
beyond age 30; the most common inherited lethal defect among white people.
Duchenne Muscular Dystrophy
• Fatal disease usually found in males,
marked by muscle weakness; minor
retardation is common; respiratory failure
and death usually occur in young
adulthood.
Hemophilia
• Excessive bleeding, usually affecting
males; in its most severe form, can lead to
crippling arthritis in adulthood
Anencephaly
• Absence of brain tissues; infants are
stillborn or die soon after birth
Spina Bifida
• Incompletely closed spinal canal, resulting
in muscle weakness or paralysis and loss
of bladder and bowel control; often
accompanied by hydrocephalus, an
accumulation of spinal fluid in the brain,
which can lead to mental retardation.
Phenylketonuria (PKU)
• Rare genetic condition that causes an
amino acid called phenylalanine to build
up in the body.
• Metabolic disorder resulting in mental
retardation
Polycystic Kidney Disease
• Infantile form: enlarged kidneys, leading to
respiratory problems and congestive heart
failure
• Adult form: kidney pain, kidney stones,
and hypertension resulting in chronic
kidney failure.
Sickle-cell Anemia
• Deformed, fragile red blood cells that can
clog the blood vessels, depriving the body
of oxygen; symptoms include severe pain,
stunted growth, frequent infections, leg
ulcers, gallstones, susceptibility to
pneumonia, and stroke