Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

QC 1 LEC & LAB > PRELIM LAB > Flashcards

PRELIM LAB Flashcards

(68 cards)

Start Studying
1
Q

MANIFESTATION OF DEFECTIVE PRODUCT?

A

improper labeling
discoloration
presence of cloudiness
presence of crystals
presence of precipitates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

defined as the sum of all factors which contributes directly or indirectly to the safety, effectiveness and reliability of the product

A

QUALITY

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

refers to the sum of all the procedures undertaken to ensure the identity and purit of a particularly pharmaceutical product

A

qualty control

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

QC control gurantees within reasonable limits that a drug product

A

free from impurities
physically and chemically stable
contains the amount of active ingr. as stated in the label
provides optimal release of active ingr. when product is administered

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

the chemical substance being analyzed

A

analyte or active constituents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

solution of a known concentration

A

titrant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

chemical which changes color at the very near the equivalent

A

indicator

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

theoretical point at which equivalent amounts of analyte and titrant have reacted

A

equivalence point or stoichiometric point

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

point at which there occurs a sudden change in some property of the reaction mixture

A

end point

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

determination of normality or molarity of a solution

A

standardization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

conc. expression and is defined as the number of equivalents of solute per liter or milliequivalents per ml of a soln

A

normality

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

expression of conc. of a soln. in terms of moles per liter

A

MOlarity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

highly purified 99.99% ultrapure compound that serves as reference material in titration

A

primary standard

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

a compound whose purity 97-98% has been established by careful chemical analysis

A

SECONDARY STANDARD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

the diff in volume or mass between the endpoint ans equivalence point

A

Titration error

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

sometimes it is necessary to add an excess of the standard titrant and the excess amount is titrated w/ a second standard titrant

A

back titration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

direct addition of titrant to analyte

A

direct titration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

adding excess amount of acid to a base to quatify w/base

A

residual titration(back titration)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

needs to perform pre-treatment before titration

A

indirect titration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

correcting errors, repeating the assay w/o the analyte

A

blank titration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

acid yellow base violet

A

bromophenol blue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

orange;yellow

A

methyl orange

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

yellow;blue

A

chlorophenol blue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

yellow;blue

A

bromothymol blue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
yellow;red
cresol red
26
colorless;red
phenolphthalein
27
principle in prep and standardization of hcl soln
neutralization-Alkalimetry
28
what prep is this based from chemical equation 2hcl + na2co3 -> 2Nacl + CO2 + h2o
Prep and standardization of hcl
29
titrant in experiment 1
hcl soln
30
analyte in experiment 1
anhydrous sodium carbonate (Na2CO3)
31
INDICATOR AND END POINT IN EXPERIMENT 1
METHYL ORANGE AND SALMON PINK ENDPOINT
32
WHAT IS EXPERIMENT 2
PREP AND STANDARDIZATION OF SODIUM HYDROXIDE SOLN
33
PRINCIPLE INVOLVED IN EXPERIMENT 2
NEUTRALIZATION ACIDIMETRY
34
TITRANT IN EXP 2
SODIUM HYDROXIDE SOLN
35
ANALYTE IN EXP 2
HCL
36
INDICATOR AND ENDPOINT IN EXP 2
PHENOLPTHALEIN AND LIGHT PINK COLOR ENDPOINT
37
refers to qualitatively assesig or quantitavely measuring the presence of, amount or functional activity of a target entity
assay
38
aspirin or?
acetylsalicylic acid
39
classification and uses of aspirin and side effects
NSAIDs analgesic (pain relief) antipyretic (reduces fever) anti-inflammatory(inhibition of the synthesis of prostaglandins) irritation of stomach or gut, indigestion and nausea
40
titrant for aspirin assay
hcl sln
41
analyte for aspirin assay
aspirin w/ sodium hydroxide soln
42
indicator and end point
phenolpthalein and disapearance of pink color
43
determination of volume of soln of a known conc.
volumetric soln
44
based on physical and chemical prop. of substance being analyzed
physiocolchemical analysis
45
separation by extraction, ppt, or other means of the constituents to be determined either in the natural state or in the form of definite compound
Gravimetric analysis
46
alkaloidal assaying, siponification
special methods
47
techniques used in physiocochemical analysis
chromatography spectrophtometric electrometric therma condumetric refratometric polarimetric
48
manifest themselves difficult to detect such as difference in judgement and skill of the analyst intangible
indeterminate error
49
nature that occur in constancr manner in each of a series of determinations personal error apparatus error poor calibration detectable and may be eliminated
determinate error
50
from where is the british pharmacopoeia and what 3 cities
from great britain london, dublin, edinburgh
51
1st american pharmacopoeia
lititz pharmacopoeia
52
who published lititz pharmacopoeia/father of USP and what date he submitted a plan for the creation of it
dr. lyman spalding jan. 6 1817
53
homeopathic pharmacopoeia of US and used the principle of similarities
dr. samuel hahnermann
54
intl. pharmacopoeia
WHO
55
YEAR THAT LITITZ WAS USED IN US ARMY
1778
56
MASSACHUSETTS MED SOCIETY PUBLISHED __ PAGES PHARMACOPOEIA ON MONOGRAPHS ON ___ DRUGS OF PHARMACEUTICAL PREPARATIONS AND WHAT YEAR
272 PAGES, 536 DRUGS AND 1808
57
DATE WHEN DRAFT PHARMACOPOEIA WAS CONSOLIDATED
JAN 1 1820
58
DATE WHEN USP ENG AND LATIN WAS PUBLISHED
DEC 15 1820
59
1ST ED. OF NF UNOFFICIAL PREPARATIONS WAS PUBLISHED
1888
60
PHARMACOP. GRABT AUTHORITY FOR SUPPLEMENTS TO USP
1990
61
DATE THE TITLE NATIONAL FORMULARY OF UNOFFICIAL PREPARATIONS WAS CHANGED TO NF, WHO WAS THE PRES. AND WHAT ACT
JUNE 30, 1906 PRES. THEODORE ROOSEVELT PURE FOOD AND DRUG ACT
62
YEAT USP DECIDED TO REVISE USP EVERY 5 YRS AND NF 10 YRS
1940 BUT NOW ITS ANNUALLY REVISED
63
YEAR USP PURCHASED NF
1975
64
1ST COMBINED COMPENDIUM WHAT USP , NF AND DATE
USP XX AND NF XV JULY 1 1980
65
WHAT ED. OF USP AND NF WAS USED TO CHANGE FROM ROMAN TO ARABIC DICTATE EDITIONS AND WAHT YR
USP 23 AND NF 18 1995
66
YR USP-NF BECAME AN ANNUAL PUBLICATION
2002
67
principles involved in assay of aspirin
Neutralization and saponification of esters
68
ester cleaved back into carboxylic acid and an alcohol by reactions of water and base
Saponification

QC 1 LEC & LAB (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions