Prelims Flashcards
(126 cards)
T or F
mood can Influence a person’s behavior and perception of the world
TRUE
Pervasive and sustained
* Feeling tone that is expressed internally
Mood
Types of Mood Disorders
Major depressive disorder/unipolar depression
Bipolar disorder
Cyclothymia and dysthymia
Hypomania
both manic and depressive
episodes or patients with manic episodes alone
Bipolar disorder
episode of manic symptoms that
does not meet the criteria for manic episode
Hypomania
as disorders that
represent less severe forms of bipolar disorder
and major depression, respectively.
Cyclothymia and dysthymia
Major ___episode:
* occurs without a history of a manic, mixed, or hypomanic episode
* must last at least 2 weeks
Depression
Characteristics of?
-changes in appetite and weight
- changes in sleep and activity
- lack of energy
- feelings of guilt
- problems thinking and making decisions
- recurring thoughts of death or suicide.
Depression
is a distinct period of an abnormally and
persistently elevated, expansive, or irritable mood
lasting for at least 1 week (or less)
Mania
Characteristics of?
A hypomanic episode:
- lasts at least 4 days
- similar to a manic episode
- except that it is not sufficiently severe to cause impairment in social or occupational functioning
- no psychotic features are present.
T or F
Manic and hypomanic are both associated with:
* inflated self-esteem
* decreased need for sleep
* Distractibility
* great physical and mental activity
* overinvolvement in pleasurable behavior
TRUE
Bipolar I disorder, Mixed Episode, Bipolar II Disorder are types of what disorder?
Mania
a clinical course of one or more manic episodes and,
sometimes, major depressive episodes.
Bipolar I disorder
a period of at least 1 week – both a manic episode and a major depressive episode occur almost daily.
Mixed Episode
- A variant of bipolar disorder – episodes of major
depression and hypomania (rather than mania)
Bipolar II Disorder
at least 2 years of depressed mood
* not sufficiently severe to fit the diagnosis of major depressive episode.
Dysthymic disorder
- at least 2 years of frequently occurring
- hypomanic symptoms cannot fit the diagnosis of manic episode
- depressive symptoms that cannot fit the diagnosis of major depressive episode.
Cyclothymic disorder
T or F
* Women
* more likely than men to present a mixed picture
* higher rate of being rapid cyclers, defined as having four or more manic episodes in a 1-year period
TRUE
- Of the biogenic amines, ___-and ____are the two neurotransmitters most implicated in the pathophysiology of mood disorders.
norepinephrine and serotonin
Downregulation or decreased sensitivity of beta-adrenergic
receptors = clinical antidepressant responses
Norepinephrine
Depletion of serotonin = precipitate depression, ( suicidal impulses :
CSF - serotonin metabolites and less serotonin uptake sites on platelets)
Serotonin
▬ Reduced in depression and increased in mania.
Dopamine
Depressive disorders are associated with several immunological abnormalities, including decreased lymphocyte proliferation
- Immunological Disturbance
- CT and MRI Brain
- abnormal hyperintensities in subcortical regions
- periventricular regions
- basal ganglia
- thalamus.
- Most common in bipolar I disorder
Structural and Functional Brain Imaging