Prenatal testing for fetal aneuploidy Flashcards
(13 cards)
1
Q
Trimester 1
A
0-12 weeks
2
Q
Trimester 2
A
13-27 weeks
3
Q
Trimester 3
A
28-birth
4
Q
full term
A
40 weeks
5
Q
1st trimester combined test
A
Done at 9-13 wks
- pregnancy associated plasma protein A
- BhCG
- nuchal translucency
noninvasive/nondx
6
Q
cell-free fetal DNA
A
10+ weeks
screens:
- trisomies
- fetal sex
indications:
- mom 35+
- previous abnormal serum/sono
- hx of previous aneuploidy
nondx
7
Q
Chorionic villus sampling
A
10-13 weeks
offers definitive karyotype
risk of spotting, pregn loss
8
Q
2nd trimester quadruple screen
A
15-20 weeks
- maternal serum alpha-fetoprotein
- estriol
- BhCG
- inhibin A
noninvasive/nondx
9
Q
Amniocentesis
A
15-20 weeks
definitive, high risk
10
Q
2nd trimester US
A
18-20weeks
learn:
- fetal growth
- fetal anatomy
- placental position
considered “soft findings”
11
Q
2 tests done at 15-20 weeks?
A
2nd trimester quadruple screen & amnio
(2nd trimester US at 18-20wks)
12
Q
2nd trimester quadruple screen results
A
13
Q
A
