prescription review Flashcards

1
Q

drugs that cause dry cough

A

ACEi (RAAS -> inc bradykinin)

methotrexate (induced pneumonitis)

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2
Q

beta-blocker + verapamil

A

sudden hypotension and asystole (rip)

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3
Q

postural hypotension

A

tamsulosin (alpha blockade)

acei

isosorbide mononitrate (venodilation)

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4
Q

what interacts with levothyroxine

A

ferrous fumarate

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5
Q

lithium toxicity

A

cerebellar dysfunction (nystagmus and dysmetria)

hyperthermia

hypernatraemia

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6
Q

drugs that case hypernatraemia

A

loop and thiazide diuretics

lithium

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7
Q

citalopram

A

max dose for adults: 40mg

max dose for >65 or hepatic impairment: 20mg

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8
Q

amiodarone and venlafaxine

A

interact with each other

arrange annual ECGs, check BP and pulse

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9
Q

breast feeding safe drugs

A

metformin

sulfonylurea - glibenclamide

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10
Q

breast feeding avoid drugs

A

aspirin - reyes syndrome

ciprofloxacin (quinolone) - arthropathy

lisinopril

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11
Q

clozapine adverse effects

A

an atypical antipsychotic

dopaminergic effects

metabolic syndrome (polydipsia, polyuria, blurred vision)

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12
Q

digoxin loading dose

A

oral 500 mcg, daily

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13
Q

doxycycline loading dose

A

oral 200 mg, daily

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14
Q

cytochrome p450 inducers

A

Phenytoin

Carbamazepine

Barbiturates

Rifampicin

Alcohol (chronic excess)

Sulphonylureas

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15
Q

cytochrome p450 inhibitors

A

Allopurinol

Omeprazole

Disulfiram

Erythromycin

Valproate

Isoniazid

Ciprofloxacin

Ethanol (acute intoxication)

Sulphonamides

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16
Q

DRESS

“drug reaction with eosinophilia and systemic symptoms”

A

allopurinol

anti epileptics: carbamazepine

sulphonamides: co - trimoxazole

17
Q
A