Previous Questions

Question 1

Encapsulated cell technology (ECT) implants consist of genetically modified cells that are encapsulated in a section of semi-permeable hollow fiber membrane. The implant has a suture loop at one end to anchor it to the sclera in the vitreo-retinal body inside the eye. The current product is 6 mm in length, roughly the size of a grain of rice. What is the role of the membrane in this device?

Answer 1

Allows for the release of therapeutic protein from the device

Question 2

Most FDA-approved cell therapy products are for which indication?

Answer 2

Hematopoietic Cell transplantation

Question 3

all FDA-approved CAR-T therapies are…

Answer 3

used to treat blood cancers
considered gene therapy

Question 4

characteristics of T cells when used in drugs as cell-based immunotherapy

Answer 4

can induce graft vs host disease
boost immune activity
safest when used autologously

Question 5

characteristic of a drug substance in CAR-T cell based therapy

Answer 5

enables the T cell to more specifically target a tumor-associated antigen once transduce

Question 6

ascorbic acid

Answer 6

antioxidant in sterile preparations