prevot Flashcards
GABA
reduces action potential firing and calms the brain down
seems to inhibit activity in the hippocampus and frontal lobe.
When Gaba is low intrusive thoughts make it difficult to concentrate and form new memories, whereas when its high increases memory consolidation.
aim prevot
using a gaba agonist would increase neural inhibition and lead to improved memory functions
imidazobenzodiazepine
participants prevot
sample of mice with memory impairment. They were either chronic stress or aged mice
Double blind study with a pre post design
results prevot
Healthy are likely to understand the differences between the two arms of the y whereas impaired will repeatedly explore the same arm of the Y
Results In both cases, there was an improvement in spatial working memory in the mice that were given the GABA agonist p for both aged and stressed .
After the study, the mice were sacrificed. The researchers found that the mice with the drug treatment showed new hippocampal cell growth, reversing the effects of stress and aging.