Primary And Secondary Structure Of Proteins Flashcards
(50 cards)
What is the primary structure of a protein?
The linear sequence of amino acids in a protein.
What bonds hold together the amino acids in the primary structure of a protein?
Peptide bonds.
True or False: The primary structure of a protein determines its overall shape and function.
True
What is the secondary structure of a protein?
The regular, repeating patterns of folding of the protein chain.
What are the two main types of secondary structure in proteins?
Alpha helix and beta sheet.
In an alpha helix, the protein chain is coiled like a ________.
Spring.
In a beta sheet, the protein chain forms a __________ structure.
Flat, sheet-like.
True or False: Secondary structure of a protein is stabilized by hydrogen bonds.
True
What amino acid is often found in turns between secondary structure elements in proteins?
Proline.
What is a beta turn or beta bend in protein secondary structure?
A sharp turn in the protein chain that reverses direction.
What is a loop or coil in protein secondary structure?
A region that does not form regular secondary structure.
What is a random coil in protein secondary structure?
A disordered region of the protein chain.
What secondary structure element is often found in the turns of a protein chain?
Beta turns.
What is a secondary structure motif in proteins?
A combination of secondary structure elements forming a recognizable pattern.
What is a protein domain in terms of secondary structure?
A distinct structural unit within a protein that may fold independently.
What is a supersecondary structure in proteins?
A combination of secondary structure elements that form a functional unit.
What is a protein fold in terms of secondary structure?
A specific arrangement of secondary structure elements that forms a stable unit.
True or False: The secondary structure of a protein is determined by the primary structure.
True
What techniques are commonly used to study protein secondary structure?
X-ray crystallography, NMR spectroscopy, and circular dichroism.
What is the Ramachandran plot used for in protein structure analysis?
To analyze the allowed regions of phi and psi angles in protein structures.
What is a helix-coil transition in protein secondary structure?
The transition between helical and disordered states in a protein.
What is a helix-turn-helix motif in protein secondary structure?
A common DNA-binding motif consisting of two alpha helices separated by a turn.
What is a beta hairpin in protein secondary structure?
A short anti-parallel beta sheet structure with a hairpin loop.
What is a helix-loop-helix motif in protein secondary structure?
A common DNA-binding motif consisting of two alpha helices separated by a loop.
