Primary Sclerosing Cholangitis

Question 1

■ Progressive destruction of intrahepatic
and extrahepatic bile ducts
■ 2/3 of cases occur in 20 to 40 years of age
■ More than 40% are asymptomatic

Answer 1

Primary Sclerosing Cholangitis

Question 2

Signs & Symptoms of Primary Sclerosing Cholangitis

Answer 2

– Pruritus
– Jaundice
– Abdominal pain
– Fatigue
– Anorexia
– Weight loss

Question 3

Complications of Primary Sclerosing Cholangitis

Answer 3

– Bacterial cholangitis
– Pigmented bile stones
– Steatorrhea
– Malabsorption
– Metabolic bone disease

Question 4

Severe complications of primary sclerosing cholangitis

Answer 4

– Cirrhosis
– Portal hypertension