Principles and pharmacology

Question 1

What are the inhalational anaesthesia used for induction

Answer 1

volatile - sevoflurane
Nitrous Oxide

Question 2

What is used for IV induction of anaesthesia

Answer 2

Propofol with or without opioid

Question 3

How does propofol work

Answer 3

acts on the GABA receptor – makes more chloride come into the cell which restricts the membrane potential from reaching threshold for excitation

Question 4

What are the potent, quick acting opioids

Answer 4

Fentanyl
Alfentanyl
Remifentanyl

Question 5

What opioids dont accumulate

Answer 5

Remifentanyl

Question 6

What opioids are slower onset and longer acting

Answer 6

Morphine

Question 7

What are the non depolarising muscle relaxants - competitive agonists at acetylcholine receptor

Answer 7

Rocuronium and atracurium

Question 8

What are the depolarising muscle relaxants - acetylcholine receptor agonist

Answer 8

Suxamethonium

Question 9

What are the reversal agents for muscle relaxants

Answer 9

Neostigmine - acetylcholine inhibitor + glycopyrrolate - muscarinic anticholinerginic

Suggamadex

Question 10

What is given in phase 2 of anaesthesia - maintenence

Answer 10

• inhilational - volatile (sevoflurane) with or without opioid
• IV - propofol with or wihout opioid
• Muscle relaxant