principles neurology Flashcards
(34 cards)
away from CNS
efferent
towards CNS
arrerent
what is a ganglion
a group of nerve cell bodies that house synapses
route of parasympathetic nerves
cranium - sacrum
parasympathetic cranial nerves
CN3, 7, 9, 10
parasympathetic neurotransmitter
ACh
parasympathetic receptor
nicotinic
short post ganglionic
ACh neurotransmitter, Muscularinic receptor
functions of the parasympathetic division
slow HR, lower BP, arousal, salivation, lacrimation, urination, digestion and defecation
short preganglionic fibre of sympathetic is from
thoracolumbar
preganglionic sympathetic receptor and neurotransmitter
ACh and nicotinic receptor
long post ganglionic symapthetic
NA nuerotransmitter activates G protein coupled adrenics
functions of the sympathetic system
increases HR and force, reduces GI motility, contrictionof sphinters, vasoconstriction but relaxation in skeleatl muscle adrealine release from the adrenal galnd, ejaculation, relaxes bronchi and decreases mucus production
preganglionic nicotinic cholinergic
central cation conducting ligand gated channel
post ganglionic muscarinic
activated by G protein receptors
g protein of M1
Gq
effect of M1
increased gastric acid secretion
g protein of m2
Gi
effect of M2
decreased HR
G protein of m3
GQ
effect of M3
increased salvary secretion and bronchial smooth muscle contraction
sympathetic nicotinic cholinergic
5 glycoprotein subunits form a central cation conducting channel activated by lingand gated cahnenls
noradrenaline trasnmission
adrenoceptor activation, NA reuptake by transporters u1 and U2
metabolism of NA
monoamine oxidase MAO and catechol-O-methyltransferase COMT
