PROCHECK

Question 1

Procheck

Answer 1

-software tool for assessing the stereochemical quality of protein structures derived from experimental methods
- Roman Laskowski and Janet M. Thornton
- evaluate the geometric accuracy and overall reliability of protein models
- part of saves server

Question 2

Purpose

Answer 2

-assess the stereochemical quality of protein structures, particularly focusing on backbone and side-chain geometry.
- checks errors or inaccuracies in bond lengths, bond angles, torsion angles, and other geometric parameters

Question 3

Functionality

Answer 3

-Ramachandran plot
- does Ramachandran analysis to evaluate the backbone dihedral angles (phi and psi) of amino acid residues in the protein structure
- identifying residues with unusual backbone conformations (shows error in protein structure)

-bond length, bond angles, torsion angles etc
-standard reference (pDB structures)

Question 4

Application

Answer 4

-structural biology
-computational biology
- drug discovery etc