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Flashcards in Prochorperazine Deck (8)
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1
Q

What type of drug is stemetil?

A

Phenothiazine antiemetic

2
Q

Stemetil acts on several neurotransmitter systems. What are they?

A
  1. Antidopamine action
  2. Alpha-adrenergic antagonism
  3. Potentials not-adrenaline
  4. Weak anticholingeric and antihistamine effects
  5. Weak seretonin antagonism
3
Q

What is the indication for stemetil?

A

For the treatment (only) of nausea and vomiting from a variety of vestibular causes including: motion sickness, migraine, vertigo, and labyrinthitis

4
Q

Stemetil adversely effects all body systems. What are those effects?

A

Gastro: constipation and dry mouth

Nervous system: drowsiness and extrapyrimidial symptoms

Cardio: hypotension, ECG changes (QT prolongation)

Respiratory: respiratory depression

5
Q

What are the 7 contraindications of stemetil?

A
  1. KSAR to phenothiazines
  2. CNS depression
  3. Shock from any cause or circulatory compromise
  4. Pregnancy
  5. < 18 years
  6. Conjunction with IV amioderone
  7. Previous oral prochloroerazine in last 8 hours
6
Q

What are the 5 precautions of stemetil?

A
  1. Renal dysfunction
  2. Parkinson’s
  3. Myasthenia gravis
  4. Epilepsy
  5. Elderly. Increased chance of dystonic reactions
7
Q

What is the dose of stemetil?

A

12.5mg deep IMI

8
Q

What is the special note with stemetil?

A

Pts should be TX due to extensive adverse effect profile