proficiency Flashcards
(176 cards)
1
Q
Acyclavir; PC?
A
Antiviral
2
Q
Acyclavir; MOA?
A
Inhibits DNA synthesis and viral replication
3
Q
Acyclavir; Indic?
A
Herpes (Shingles and Chickenpox) Bells Palsy
4
Q
Acyclavir; Admin?
A
Oral and IV
5
Q
Acyclavir; Effects?
A
Acute Kidney Injury, neurotoxicity, thrombotic microangiopathy
6
Q
Acyclavir; MP?
A
Hydration, urinalysis, BuN, creatinine, output
7
Q
Amiodarone; PC?
A
antiarrhythmic, agent class 3
8
Q
Amiodarone; MOA?
A
inhibits adrenergic stimulation, prolongs action potential and refractory period
9
Q
Amiodarone; Indic?
A
ventricular arrhythmias (VFib) (VTach) / A Fib
10
Q
Amiodarone; Admin?
A
Oral, IV, less than or equal to 2 mg/mL
11
Q
Amiodarone; Effects?
A
Bradycardia, hypotension, N/V, pulmonary toxicity
12
Q
Amiodarone; MP
A
BP, HR, EKG, (Potassium/ magnesium)
13
Q
Baclofen; PC?
A
Skeletal muscle relaxant
14
Q
Baclofen; MOA?
A
inhibits transmission of mono/poly synaptic reflexes at spinal cord level
15
Q
Baclofen; Indic?
A
spasticity / hiccups, muscle spasms
16
Q
Baclofen; Admin?
A
Bolus (50 mcg/ mL); oral (granules/ solution)
17
Q
Baclofen; Effects?
A
N/V, asthenia, confusion, dizziness, headache, hypotonia
18
Q
Baclofen; MP?
A
EEG, S/S of withdrawal altered mental status, spasticity, hallucination, fever, tachycardia
19
Q
Benazepril; PC?
A
Angiotensin - converting enzyme (ACE) inhibitor, antihypertensive
20
Q
Benazepril; MOA?
A
Inhibition of angiotensin 1 being converted to 2 - increase of plasma renin activity and reduction in aldosterone secretion
21
Q
Benazepril; Indic?
A
Hypertension
22
Q
Benazepril;Admin?
A
Oral
23
Q
Benazepril; Effects?
A
Acute Kidney Injury, angioedema, cough, hyperkolemia
24
Q
Benazepril; MP?
A
BP, BuN, Creatinine, electrolytes, airway
25
Bisoprolol; MOA?
Competitively blocks beta-1 receptors
26
Bisoprolol; PC?
Beta 1 Blocker, antihypertensive
27
Bisoprolol; Indic?
Hypertension/ angina, A Fib/ Flutter, Heart Failure with reduced EF, ventricular arrhythmia,
28
Bisoprolol; Admin?
oral without to regard to meals, smallest size 5 mg
29
Bisoprolol; Effects?
bradyarrhythmia, brnochospams, CNS. masking hypoglycemia, withdrawal
30
Bisoprolol; MP?
BP, HR, EKG, S/S of bronchospasm, glucose, mental alertness
31
bumetanide PC
loop diuretic; antihypertensive
32
Bumetanide MOA
inhibits reabsorption of sodium & chloride in loop of henle
33
Bumetanide USE
edema or volume overload
34
bumetanide ADMIN
IV-slowly 0.5 to 1mg over 1-2 mins
oral- w/ or w/o food, 1-2 days in between
35
Bumetanide A.EFFECTS
AKI, electrolyte/fluid loss, ototoxicity, hypo-chloremia/kalemia, hyperuricemia
36
Bumetanide MP
BP, electrolytes, kidney function, I/O
37
bupropion PC
dopamine/norepinephrine-reuptake inhibitor; antidepressant
38
bupropion MOA
weak inhibitor of the neuronal uptake of dopamine/norepinephrine
39
bupropion USE
MDD, SAD smoking cessation/ ADHD, bipolar, depressive episode
40
bupropion ADMIN
oral-do not crush, immediate release- 3/4 daily w/ 6hrs inbetween
41
bupropion A.EFFECTS
mania (hypo), CNS stimulation, abnormal thinking, seizure, ocular, wt loss
42
bupropion MP
BP, body wt, suicidality, renal/hepatic function, HR
43
captopril PC
ACE inhibitor; antihypertensive
44
captopril USE
acute coronary syndrome, HF w/ reduced EF, HTN, CKD/ aldosteronism
45
captopril ADMIN
oral- @ least 1 hour before meals
46
captopril A.EFFECTS
AKI, angioedema, cough, hyperkalemia, hematologic effects
47
captopril MP
BP, BUN, creatinine, electrolytes, airway obstruction
48
carbamazepine PC
antimanic/ antiseizure agent
49
carbamazepine MOA
depress activity in nucleus ventralis of thalamus or decrease synaptic transmission
50
carbamazepine USE
bipolar, focal/generalized seizures, neuropathic pain/
bipolar major depression
51
carbamazepine ADMIN
w/food, suspension
52
Dorzolamide; PC
Carbonic Anhydrase Inhibitor, Antiglaucoma
53
Dorzolamide; MCA
Inhibition of enzyme carbonic anhydrase II & IV in ciliary epithelium
54
carbamazepine MP
CBC, renal/liver function, ophthalmic exam
55
losartan ADMIN
w/o regards to meals but @ same time everyday
56
losartan A.EFFECTS
AKI, hyperkalemia
57
Dorzolamide; Indic
ocular hypertension / open- angel glaucoma
58
Dorzolamide; Admin
59
Dorzolamide; Effects
Burning, Discomfort, Stinging
60
Dorzolamide; MP
Eye Exams, IOP
61
Fentanyl; PC
Opioid, analgesic
62
Fentanyl; MOA
Binds with stereospecific receptors at sites without CNS
63
Fentanyl; Indic
Pain management
64
Fentanyl; Admin
IM / IV - slowly over 1 to 2 minutes
65
Fentanyl; Effects
Constipation, wD, respiratory depression, peripheral edema, dehydration
66
Fentanyl; MP
Pain, Respiratory/ Mental status, BP, HR, GI symptoms
67
Glipizide; PC
Antidiabetic agent, sulfonylurea,
68
Glipizide; MOA
Stimulates insulin release from pancreatic beta cells, reduces glucose output from liver
69
Glipizide; Indic
DM II
70
Glipizide; Admin
30 minutes before meal
71
Glipizide; A.Effects
Cardiovascular, hyperglycemia, sulfa allergy
72
Glipizide; MP
S/S hypoglycemia (fatigue, excessive hunger, sweating, numbness of extremities)
73
Hydroxyzine; PC
Histamine H 1 Antagonist, antiemetic
74
Hydroxyzine; MOA
Competes with histamine H1 receptor sites on effector cells
75
losartan MP
BP, electrolytes (potassium), creatinine, BUN
76
metoclopramide PC
serotonin 5-HT4 receptor agonist (antiemetic) dopamine agonist
77
metoclopramide MOA
blocks dopamine & serotonin receptors; enhances response to acetylcholine
78
metoclopramide USE
chemo n/v, diabetic gastroparesis/
GERD
79
metoclopramide ADMIN
IM/IV, nasal, oral- 30mins before meals
80
metoclopramide A.EFFECTS
CNS depression, extrapyramidal symptoms
81
metoclopramide MP
signs of TD, extrapyramidal symptoms, mental status
82
clindamycin PC
antibiotic, lincosamide
83
clindamycin MOA
inhibits bacterial protein synthesis
84
clindamycin USE
infections- bone, joint, gynecological, intraabdominal, lower respiratory, septicemia
85
clindamycin ADMIN
IM-rotate sites
IV- 30mg/min
oral- w/full glass of water
86
clindamycin A.EFFECTS
c-dif
87
clindamycin MP
bowel freq
liver/renal function
88
mirtazapine PC
alpha-2 antagonist, antidepressant
89
mirtazapine MOA
increased release of norepinephrine & serotonin
90
carbamazepine A.EFFECTS
blood dyscrasias, cardiac (HF), hyponatremia, suicidal, n/v, ataxia, dizzy/drowsiness
91
cimetidine PC
histamine H2 antagonist
91
cimetidine MOA
inhibition of H2 receptors of gastric parietal cells resulting in reduced gastric secretions
92
cimetidine USE
GERD, heartburn, peptic ulcer disease/
interstitial cystic/bladder cancer
93
cimetidine ADMIN
w/meals
94
cimetidine MP
CBC, gastric PH, signs of confusion, GI bleeding
95
mirtazapine USE
MDD/
h/a, panic disorder
96
Hydroxyzine; Indic
Anxiety, pruritus, urticaria
97
Hydroxyzine; Admin
only IM or oral
98
Hydroxyzine; Effects
CNS depression, QT prolongation, acute generalized exanthematous putulosis
99
Hydroxyzine; MP
Mental status, BP, S/S allergies
100
Losartan; PC
Angiotensin II receptor blocker, antihypertensive
101
Losartan; MOA
Blocks vaso constrictor and aldosterone- secreting effects angiotensin II
102
Losartan; Indic
HTN, proteinic CKD (non-diabetic), HF with reduced EF
103
mirtazapine ADMIN
oral tablet w/o regards to meals, don't crush
104
mirtazapine A.EFFECTS
mania (hypo), movement disorders, orthostatic hypotension, SI, wt gain, sexual dysfunction, constipation, xerostomia, drowsiness
105
mirtazapine MP
CBC, renal/hepatic function, weight
106
misoprostol PC
prostaglandin
107
misoprostol MOA
synthetic- replaces protective prostaglandins consumed w/p-inhibiting therapies
108
misoprostol USE
prevention gastric ulcers, termination of pregnancy/
labor induction
109
misoprostol ADMIN
oral tabs
110
misoprostol A.EFFECTS
abd pain, diarrhea, DO NOT USE DURING PREG
111
misoprostol MP
fetal HR, uterine activity, blood loss
112
morphine PC
analgesic opioid
113
morphine MOA
binds to opioid receptors in CNS
114
morphine USE
pain management/
dyspnea, cough
115
morphine ADMIN
oral-don't crush
IV slow over 4-5 mins
116
morphine A.EFFECTS
constipation , neurotoxicity, pruritus, respiratory depression, WD
117
morphine MP
pain control, respiratory/mental status, BP, signs of misuse
118
nortriptyline PC
tricyclic antidepressant
119
nortriptyline MOA
increase synaptic concentration of serotonin &/or norepinephrine
120
nortriptyline USE
MDD/
h/a, IBS, migraine, smoking cessation, pain
121
nortriptyline ADMIN
oral- w/o regards to food
122
nortriptyline A.EFFECTS
SI, CNS depression, ocular effects, orthostatic hypotension, hyponatremia
123
nortriptyline MP
sodium, BP, HR, mental status, weight,
124
ondansetron PC
selective 5-HT3 receptor antagonist; antiemetic
125
ondansetron MOA
blocks serotonin
126
ondansetron USE
chemo n/v/
diarrhea
127
ondansetron ADMIN
oral, IM/IV
128
ondansetron A.EFFECTS
constipation, h/a, QT prolongation
129
ondansetron MP
EKG, heart failure, potassium/magnesium
130
pentoxifylline PC
blood viscosity reducer agent
131
pentoxifylline MOA
increases blood flow to affected microcirculation
132
pentoxifylline USE
intermittent claudication (pain in legs due to reduced circulation) /
venous leg ulcers
133
pentoxifylline ADMIN
oral w/food, don't crush
134
pentoxifylline MP
renal function, hemoglobin, hematocrit,
135
phenobarbital PC
barbiturate; antiseizure
136
phenobarbital MOA
depress sensory cortex
137
phenobarbital USE
sedation, seizures/
alcohol WD
138
phenobarbital ADMIN
IV, IM, orally
139
phenobarbital A.EFFECTS
respiratory depression, SI, hypotension, bradycardia, drowsiness, vertigo
140
phenobarbital MP
s/s suicidality, CNS status, phenobarbital concentration
141
pioglitazone PC
thiazolidinedione; antidiabetic
142
pioglitazone MOA
improving target cell response to insulin
143
pioglitazone USE
DM II
144
pioglitazone ADMIN
oral- w/o regards to meals
145
pioglitazone A.EFFECTS
bladder cancer, fractures, HF/edema, hepatic failure, hypoglycemia, URI
146
pioglitazone MP
s/s HF, rapid wt gain
147
pravastatin PC
HMG-CoA reductase inhibitor; antilipemic
148
pravastatin MOA
inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A
149
pravastatin USE
hypercholesterolemia, prevention atherosclerotic/
post heart/kidney transplant,
150
pravastatin A.EFFECTS
URI, musculoskeletal pain, hepatic effects
151
pravastatin ADMIN
oral w/o regards to meals
152
pravastatin MP
lipid panel
153
sulfasalazine PC
5-aminosalicylic acid derivative; antirheumatic
154
sulfasalazine MOA
modulates chemical mediators of inflammatory response
155
sulfasalazine USE
rheumatoid arthritis, ulcerative colitis/
crohns, psoriatic arthritis, ankylosing spondylitis,
156
sulfasalazine ADMIN
oral- after meals
157
sulfasalazine A.EFFECTS
n/v/d, abdominal pain, blood dyscrasias (disorders), rash, h/a
158
sulfasalazine MP
CBC w/differential
159
sumatriptan PC
serotonin 5-HT 1B,1D receptor agonist; antimigraine
160
sumatriptan MOA
selective agonist for serotonin, causes vasoconstriction reduces inflammation
161
sumatriptan USE
cluster h/a, migraine/
cyclic vomiting syndrome
162
sumatriptan ADMIN
NOT IV/IM!!
subq, [intranasal powder, solution, spray]
163
sumatriptan A.EFFECTS
cardiac arrhythmias/events, strokes, dizziness, drowsiness, vertigo, serotonin syndrome,
164
sumatriptan MP
mental status, BP, neuromuscular changes, GI symptoms, seizures,
165
temazepam PC
benzodiazepine
166
temazepam MOA
binds to receptors on postsynaptic GABA neuron @ several sites
167
temazepam USE
insomnia
168
temazepam ADMIN
oral capsule
169
temazepam MP
respiratory/cardiovascular status
170
verapamil PC
calcium channel blocker; anti-anginal, arrhythmic, hypertensive
171
verapamil MOA
inhibits calcium ion from entering slow channels, relaxes coronary smooth muscle,
172
verapamil USE
angina, a fib/flutter, HTN, supraventricular tachycardia, chest pain, h/a, migraine,
173
verapamil ADMIN
oral, IV push over less than/equal to 2 mins
174
verapamil A.EFFECTS
acute decompensated HF, bradyarrhythmias, h/a, hepatic effects
175
verapamil MP
BP, HR, liver/kidney function
