Progestins Flashcards by Daniel Allen | Brainscape

Q

Norethindrone and norethindone acetate

estrogenic?
progestational?
androgenic?

A

estrogenic: ++
progestational: ++
androgenic: ++

1st gen

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Q

norgestrel

estrogenic?
progestational?
androgenic?

A

estrogenic: 0
progestational: +++
androgenic: +++

1/2 gen

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Q

levonorgestrel

estrogenic?
progestational?
androgenic?

A

estrogenic: 0
progestational: ++++
androgenic: +++

2nd gen

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Q

norgestimate

estrogenic?
progestational?
androgenic?

A

estrogenic: 0
progestational: ++
androgenic: ++

3rd gen

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Q

desogestrel

estrogenic?
progestational?
androgenic?

A

estrogenic: +/-
progestational: ++++
androgenic: ++

3rd gen

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Q

drospirenone

estrogenic?
progestational?
androgenic?

A

estrogenic: 0
progestational: +/-
androgenic: 0

4th gen

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Q

Segesterone acetate

estrogenic?
progestational?
androgenic?

A

estrogenic: 0
progestational: +/-
androgenic: 0

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Q

Raises HDL and lowers LDL?

A

norethindrone and norethindone

1st gen

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Q

Androgenic ADRs are common (acne, hirsutism)?

A

norgestrel

1/2 gen

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Q

Most widely prescribed?

A

levonorgestrel

2nd gen

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Q

Negative impact on lipids?

A

levonorgestrel

2nd gen

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Q

Used for emergency contraception?

A

levonorgestrel

2nd gen

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Q

Associated with a slightly increased risk of thrombosis?

A

norgestimate, desogestrel

3rd gen

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Q

FDA approved for acne?

A

norgestimate

3rd gen

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Q

Higher risk of blood clots according to FDA?

A

drospirenone

4th gen

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Q

Structurally similar to K+ sparing diuretic?

A

drospirenone

decreased bloating, weight gain, PMS symptoms

4th gen

Q

Can cause hyperkalemia?

A

drospirenone

4th gen

Q

FDA approved for PMDD?

A

drospirenone

4th gen

Q

Newly FDA approved in one year ring product?

A

segesterone acetate

4th gen

Q

AEs associated with progestins:

bloating

estrogenic?
progestational?
androgenic?

A

estrogenic

Q

AEs associated with progestins:

nausea/vomiting

estrogenic?
progestational?
androgenic?

A

estrogenic

Q

AEs associated with progestins:

breakthrough bleeding

estrogenic?
progestational?
androgenic?

A

estrogenic

Q

AEs associated with progestins:

irritability

estrogenic?
progestational?
androgenic?

A

estrogenic

Q

AEs associated with progestins:

headache

estrogenic?
progestational?
androgenic?

A

estrogenic and progestational

Q

AEs associated with progestins:

hypertension

estrogenic?
progestational?
androgenic?

A

estrogenic and progestational

Q

AEs associated with progestins:

breast pain/tenderness

estrogenic?
progestational?
androgenic?

A

progestational

Q

AEs associated with progestins:

Acne/oily skin

estrogenic?
progestational?
androgenic?

A

androgenic

Q

AEs associated with progestins:

weight gain

estrogenic?
progestational?
androgenic?

A

androgenic

Q

AEs associated with progestins

hirsutism

estrogenic?
progestational?
androgenic?

A

androgenic

Q

AEs associated with progestins:

fatigue

estrogenic?
progestational?
androgenic?

A

androgenic

Q

AEs associated with progestins:

depression

estrogenic?
progestational?
androgenic?

A

androgenic