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1
Q

What is the market description for Small Molecule Discovery?

A

Characterization and analysis of small molecules in Discovery including screening libraries for purity/ID, Reaction Monitoring, and general support of medicinal chemistry.

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2
Q

What typical applications are included in Small Molecule Discovery?

A

Purity/ID screening, reaction monitoring, physicochemical property profiling, and early pre-clinical formulation development.

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3
Q

What instruments are typically used in Small Molecule Discovery?

A

UV, Single Quad / QDA or Tof/Qtof with LC or SFC and OpenLynx, Open Access or ProfileLynx.

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4
Q

What is the market description for Small Molecule Pharmaceutical Development?

A

Characterization and analysis of small molecules in Development including Method Development, impurity profiling, and formulation development.

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5
Q

What typical applications are included in Small Molecule Pharmaceutical Development?

A

Method Development/Transfer/Validation, impurity profiling, forced degradation, and stability assessment.

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6
Q

What instruments are typically used in Small Molecule Pharmaceutical Development?

A

UV, Single Quad / QDA, Tandem Quad, QTof with LC or SFC using Empower or MassLynx.

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7
Q

What is the market description for Pharmaceutical Quality Control for Small Molecule therapies?

A

QC involves determining the acceptability of each batch for release and assessing the suitability of incoming components.

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8
Q

What typical applications are included in Pharmaceutical Quality Control for Small Molecule therapies?

A

Determining a compound’s identity, strength, purity, and other quality characteristics.

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9
Q

What instruments are typically used in Pharmaceutical Quality Control for Small Molecule therapies?

A

LC and SFC using UV, PDA, ELSD and/or sometimes Single Quad (QDa).

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10
Q

What is the market description for Large Molecule Proteins - Discovery & Development?

A

Characterization and analysis of protein-based biopharmaceuticals like monoclonal antibodies and peptides.

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11
Q

What typical applications are included in Large Molecule Proteins - Discovery & Development?

A

Intact and subunit protein analysis, glycan characterization, and peptide mapping.

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12
Q

What instruments are typically used in Large Molecule Proteins - Discovery & Development?

A

Analytical scale UPLC, UV, FL optical detection, and routine Tof and Q-Tof.

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13
Q

What is the market description for Large Molecule Proteins - Bioprocessing?

A

Analysis in upstream and downstream process development for protein-based biopharmaceuticals.

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14
Q

What typical applications are included in Large Molecule Proteins - Bioprocessing?

A

Clone selection, process understanding, and process control.

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15
Q

What instruments are typically used in Large Molecule Proteins - Bioprocessing?

A

Analytical scale LC, UV, FL optical detection, and routine Tof and Q-Tof.

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16
Q

What is the market description for Large Molecule Proteins - QAQC?

A

Analysis for the quality control of protein-based biopharmaceuticals for clinical studies or sales release.

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17
Q

What typical applications are included in Large Molecule Proteins - QAQC?

A

Quality control testing and ongoing stability assessments of drugs and products.

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18
Q

What instruments are typically used in Large Molecule Proteins - QAQC?

A

Analytical scale LC, UV, FL optical detection, and mass detector using Empower.

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19
Q

What is the market description for Large Molecule New Modalities - Discovery & Development?

A

Characterization and analysis of biopharmaceuticals in development, including peptides and proteins.

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20
Q

What typical applications are included in Large Molecule New Modalities - Discovery & Development?

A

Amino acid analysis, peptide mapping, and testing for process impurities.

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21
Q

What instruments are typically used in Large Molecule New Modalities - Discovery & Development?

A

UV, FL, Tof/Qtof with UPLC using Empower or MassLynx.

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22
Q

What is the market description for Large Molecule New Modalities - Bioprocessing?

A

QC involves determining the acceptability of each batch for release and assessing suitability of components.

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23
Q

What typical applications are included in Large Molecule New Modalities - Bioprocessing?

A

Quality control procedures ensuring identity, strength, purity, and effectiveness.

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24
Q

What instruments are typically used in Large Molecule New Modalities - Bioprocessing?

A

LC and SFC using UV, PDA, ELSD and/or sometimes Single Quad (QDa).

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25
What is the market description for Large Molecule New Modalities - QAQC?
Analysis of all Biopharmaceutical drugs that are approved for sale.
26
What typical applications are included in Large Molecule New Modalities - QAQC?
Quality control testing and ongoing stability assessments of drug products.
27
What instruments are typically used in Large Molecule New Modalities - QAQC?
UV, FL and single quad with UPLC using Empower.
28
What is the market description for GLP-1 Disc/Dev?
Characterization and analysis of synthetic peptides including GLP-1 agonists.
29
What instruments are typically used in GLP-1 Disc/Dev?
HPLC, UPLC, UPC2 or patrol, and Tandem Quadrupole or Single Quadrupole.
30
What is the market description for GLP-1 QA/QC?
Analysis of all synthetic peptides including GLP-1 agonists that are approved for sale.
31
What typical applications are included in GLP-1 QA/QC?
Quality control testing and ongoing stability assessments of drug products.
32
What instruments are typically used in GLP-1 QA/QC?
HPLC, UPLC, UPC2 or patrol, and Tandem Quadrupole or Single Quadrupole.
33
What is the market description for Fine and Specialty Chemicals?
Accounts concerned with compounds such as solvents, monomers, dyes, and formulated products.
34
What instruments are typically used in Fine and Specialty Chemicals?
HPLC, UPLC and UPC2 using UV, ELSD, PDA and/or Single Quad with Empower.
35
What is the market description for Polymers?
Accounts concerned with bulk polymers for industrial use and polymer products.
36
What instruments are typically used in Polymers?
HPLC, UPLC and UPC2 using UV, ELSD, PDA and/or Single Quad with Empower.
37
What is the market description for Energy?
Accounts concerned with fuel products and feedstocks including crude oils and biofuels.
38
What instruments are typically used in Energy?
HPLC, UPLC and UPC2 using UV, ELSD, PDA and/or Single Quad with Empower.
39
What is the market description for Agrochemicals Discovery Development Manufacturing?
Accounts concerned with research, development, and manufacture of crop protection products.
40
What instruments are typically used in Agrochemicals Discovery Development Manufacturing?
HPLC, UPLC and UPC2 using UV, ELSD, PDA and/or Single Quad with Empower.
41
What is the market description for Cosmetics & Personal Care?
Accounts concerned with research, development, and manufacture of cosmetic and personal care products.
42
What instruments are typically used in Cosmetics & Personal Care?
HPLC, UPLC and UPC2.
43
What is supported in synthetic chemistry development?
Development of chiral and achiral compounds, impurity analysis, purification, and structural characterization.
44
What is the role of metabolite and active ingredient trace analysis?
Supports compound registration.
45
What types of analysis are included in Cosmetics & Personal Care?
Analysis of incoming raw materials and natural products, including plant/botanical extracts.
46
What instruments are used in Cosmetics & Personal Care analysis?
HPLC, UPLC, UPC2, Qtof, Tandem Quads, Thermal Analyzers, Rheometers, and more.
47
What is the focus of Inorganics?
Research, development, and manufacture of inorganic products like metals, ceramics, and glasses.
48
What instruments are utilized in Inorganics testing?
Thermal Analyzers, Dilatometer, HPLC, and Mass Spec.
49
What does PFM stand for?
PFAS for Materials Science.
50
What is the focus of PFAS for Materials Science?
Quantification and characterization of PFAS in materials and consumer products.
51
What types of analysis are performed in Food & Beverage Quality Control?
Testing related to food and beverage ingredients, compositional claims, and quality control.
52
What instruments are used in Food Research?
HPLC, UPLC, UPC2, ionKey, APGC, and various MS platforms.
53
What is the purpose of Food Safety testing?
Testing for contaminants and adulterants in food or agricultural products.
54
What types of contaminants are screened in Food Safety?
Pesticides, veterinary drug residues, mycotoxins, and allergens.
55
What does EHS stand for?
Environment & Homeland Security.
56
What is tested in EHS?
Contaminants and pollutants in water, air, or soil.
57
What types of analyses are performed in Botanicals & Nutritional Supplements?
Analyses of natural products for dietary or nutritional uses.
58
What does PFA stand for?
PFAS For Environmental.
59
What is the focus of PFAS For Environmental?
Quantification and characterization of PFAS in various environmental samples.
60
What does PFF stand for?
PFAS for Food.
61
What is tested in PFAS for Food?
Quantification and characterization of PFAS in food, beverages, and food contact materials.
62
What is the purpose of Neonatal Screening?
Screening newborns for metabolic, endocrine, and genetic disorders.
63
What platforms are used in Clinical Toxicology?
IVD Tandem quadrupole LC-MS platforms and Toxicology Screening Application Solution.
64
What is the focus of Endocrinology testing?
Measurement of hormones and investigation into the endocrine system.
65
What does TDM stand for?
Therapeutic Drug Monitoring.
66
What is the goal of TDM?
Improving patient care by adjusting drug doses.
67
What does CDO stand for?
Other Therapeutic Area.
68
What is the focus of Forensic Testing?
Screening and quantitation of drugs of abuse in physiological samples.
69
What is analyzed in Oncology?
Cancer biomarkers using tandem quadrupole LC-MS platforms.
70
What is the focus of Neurology testing?
Screening for neurodegenerative disease biomarkers and neuroinflammatory disorders.
71
What does OMX stand for?
Omics.
72
What is the purpose of Omics in biomedical research?
Advancing the understanding of cellular biochemistry and markers of disease.
73
What is the use of LC-MS and mass spectrometry imaging in biomedical research?
The use of LC-MS and mass spectrometry imaging based systems for basic and translational biomedical research to advance the understanding of cellular biochemistry, human health, and markers of disease.
74
What types of omics are used in biomedical research?
Targeted and untargeted omics such as Metabolomics, Lipidomics, Proteomics, Glycomics, microbiome, and MS imaging for discovery, characterization, quantification, and visualization of molecular markers.
75
What types of analyses are performed in biomedical research?
Analysis can be the study of single molecules or molecular interactions, groups of related molecules, and/or untargeted discovery and visualization of molecular markers.
76
What are the separation techniques used in biomedical research?
HPLC, UPLC, UPC2, ionKey, APGC.
77
What types of mass spectrometry are used in biomedical research?
Tandem Quadrupole, Single Quadrupole, Qda, QTof, Ion Mobility, MALDI/DESI Imaging.
78
What informatics tools are used in biomedical research?
Empower, MassLynx, Progenesis, Symphony, HDI, LiveID, UNIFI.
79
What types of kits are used in biomedical research?
Any Waters or third-party research-use only kits (e.g. Biocrates MxP500, Biognosys PlasmaDive).
80
What is the focus of traditional medicine research?
Study of all plants, marine, microbial, fungal natural products for the discovery of new therapeutics using untargeted omics approaches.
81
What are the separation techniques used in traditional medicine research?
UPLC, UPC2, APGC.
82
What types of mass spectrometry are used in traditional medicine research?
Tandem Quadrupole, Single Quadrupole, Qda, QTof, Ion Mobility, MALDI/DESI Imaging.
83
What informatics tools are used in traditional medicine research?
MassLynx, Progenesis, Symphony, UNIFI, LiveID, HDI.
84
What is the focus of Andrew Automation Core?
Serial Dilution, Concentration Normalisation, Standard Curve Preparation, Plate Reformatting, Cherry Picking, Sample Aliquoting, Plate Filling, Tube Filling, Endotoxin Testing.
85
What is the focus of Andrew Automation Genomic?
PCR Prep, PCR Clean-up, Plasmid DNA Purification.

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