Prokaryotic cell Flashcards
(17 cards)
what are the 2 prokaryote types of cells
Bacteria and Archaea
Nucleoid (Prokaryotic)
Contains cells DNA in single circular chromosone
Plasmid (Prokaryotic)
Small, circular DNA molecules separate from the chromosomal
DNA, often genes that provide antibiotic resistance
Cell Wall (Prokaryotic)
Structural support and protection, prevents osmotic lysis (swelling and bursting of cell due to excess water intake)
Peptidoglycan (Prokaryotic)
=cell wall, and is mesh like layer outside plasma membrane(=> strength and rigidity)
Plasma membrane (Prokaryotic)
lipid bilayer that controls the movement of substances in and out of the cell
Ribosomes (Prokaryotic)
Sites of protein synthesis, translate mRNA into polypeptides
Pilus (Prokaryotic)
Hair-like structures that allow for attachment to surfaces and conjugation (transfer of DNA between bacteria(using conjugative pili))
Flagellum (Procaryotic)
Provides mobility
Capsule (Prokaryotic)
Most outer layer, protects the cell from desiccation and phagocytosis by host immune cell => increases virulence in pathogenic species
Cytoplasm (Procaryotic)
Jelly like substance that contains everything
2 main classes of bacteria
Gram + and Gram -
Gram + details
- Thick Peptidoglycan Layer
- Excessive Cross-Linking
- No Outer Membrane
- Teichoic Acids in cell wall => overall charge and rigidity
- Color : purple
Gram - details
- Thin Peptidoglycan Layer
- Less Cross-Linking
- Outer Membrane with lipopolysaccharides important for protection and strzuctural integrity
- Periplasmic Space (space between the outer membrane
and the plasma membrane) - Color : red or pink
What does Beta-Lactams (Penicillin) do to peptidoglycan
Targets transpeptidase enzymes (also known as penicillin-binding proteins, PBPs), preventing cross-linking of the
peptidoglycan strands => weakens the cell wall, => cell lysis
What does Glycopeptides (Vancomycin) do to peptidoglycan
Bind to the D-Ala-D-Ala terminus of the peptide chain, preventing cross-linking and incorporation of new subunits into
the peptidoglycan matrix.