Prostate Flashcards

(156 cards)

1
Q

How many lobes is the prostate divided into?

A

Five

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2
Q

Carcinoma of the prostate is most often found in the:

A

Peripheral zone

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3
Q

Elevated prostate specific antigen (PSA) is found in patients with?

A

Carcinoma

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4
Q

What is the most common prostate condition in a male over the age of 50?

A

Benign prostatic hypertrophy (BPH)

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5
Q

A 52 year old man presents with Hydronephrosis and asymmetric prostate enlargement. This is most likely consistent with:

A

Carcinoma

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6
Q

The seminal vesicles are located:

A

Posterior to the bladder,
superior to the prostate,
Lateral to ductus deferens

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7
Q

Benign prostatic hypertrophy usually occurs in the:

A

Transitional zone

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8
Q

Transverse images at the base of the prostate are used to:

A

Image the seminal vesicles

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9
Q

A male patient presents sonographically with a hypervascular noncompressible mass noted in the peripheral zone and ejaculatory ducts filled with calculi. The most likely diagnosis is:

A

Prostatitis

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10
Q

Male infertility can result from:

A

Blocked seminal vesicles, prostatitis, or prostatic lesions

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11
Q

What PSA levels would indicate a strong suspicion for cancer?

A

Greater than 20 ng/mL

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12
Q

What zone of the prostate is comprised of 70% glandular tissue and is the most common site for prostate cancer and prostatitis?

A

Peripheral zone

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13
Q

Mr. Smith is a 54-year-old male who presents to the ER with a fever, stating he has been experiencing rectal tenderness accompanied by pain in how lower abdomen for the first time that began a few days ago. Lab results indicate normal PSA and no other abnormal indicators. Sonographic examination reveals a hypoechoic appearance of the peripheral zone. What is the diagnosis?

A

Acute prostatitis

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14
Q

A 30 year old male came in to discuss infertility issues due to him and his wife not being able to conceive for over a year now, and his wife has confirmed that she’s able to have children. The sonographer visualized a heterogeneous peripheral zone and irregularity shaped focal mass with calcifications and hypervascularity within the prostate. What is the most likely diagnosis?

A

Chronic prostatitis

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15
Q

While a 70 year old African American male patient was at his annual physical exam, a palpable mass was detected during the digital rectal exam. The labs revealed that the PSA was elevated to 22 ng/mL. The patient presented sonographically with a thickened bladder wall and a hyperechoic nodule, in the peripheral zone. Color Doppler revealed hypervascularity. What is the most likely prognosis?

A

Prostate carcinoma

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16
Q

Which zone of the prostate is most commonly involved in prostate adenocarcinoma?

A

Peripheral zone

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17
Q

On transrectal ultrasound, which feature is most suggestive of clinically significant prostate cancer ?

A

Hypoechoic lesion in the peripheral zone with irregular margins.

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18
Q

A 64 year old male arrived for an ultrasound exam with complaints of pain. In the scrotum and thighs. He stated he has been experiencing an urgency to urinate frequently. While scanning, you see a heterogeneous focal mass in the peripheral zone with calcifications. What is the likely diagnosis?

A

Chronic prostatitis

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19
Q

The prostate consists of five lobes and four zones that account for glandular tissue. Which zone surrounds the urethra and is more likely for cancer to originate?

A

Transitional zone

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20
Q

What best describes the sonographic appearance of the prostate following a TURP procedure performed for benign prostatic hypertrophy?

A

Anechoic space in the area of the prostatic urethra in the center of the prostate

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21
Q

A 65 year old male presents with difficulty urinating, weak urine stream, and lower back pain. Laboratory results show elevated prostate-specific antigen (PSA) levels, and digital rectal exam reveals a firm, irregular prostate. Sonographic evaluation reveals an asymmetrically enlarged prostate gland with local extension into the seminal vesicles. What is the most likely diagnosis?

A

Prostate carcinoma

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22
Q

A 66 year old man presents with decreased urinary stream and incomplete bladder emptying. Sonographic evaluation reveals a hypoechoic, homogeneous enlargement in the prostates transitional zone. Which type of BPH is most likely?

A

Stromal hyperplasia

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23
Q

A 70 year old man presents with difficulty urinating and receives an ultrasound showing a hypoechoic anlargement surrounding the proximal urethra. The affected zone makes up 5–10% of glandular tissue and is the most common site of benign prostatic hypertrophy. Which zone is most likely involved?

A

Transitional zone

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24
Q

A 50 year old African American male comes in for a transrectal ultrasound for urinary frequency and recurrent lower back pain. His labs also show an increased PSA. When you start the exam, you look at the peripheral zone and see hypoechoic nodules. You also measure his prostate, and it is enlarged. What would be the most likely diagnosis?

A

Prostate carcinoma

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25
A 30 year old male comes in for a checkup, he explains to his doctor that he has been experiencing painful ejaculation and rectal discomfort. He also states that he noticed that there was blood in his sperm last time he ejaculated. The doctor gives him a referral for a prostate ultrasound. The sonographer starts the exam and sees an anechoic cystic structure attached by a stalk extending into the prostate lateral from the midline and superior to the base of the prostate gland. The cystic structure has smooth and regular borders, contains calcifications, and is 4cm in size. What is the most likely diagnosis?
Müllerian duct cyst
26
A 50 year old male patient comes in for a prostate ultrasound. He explains he is there because during a digital rectal exam at his doctors office, a mass was felt on the prostate. His lab work shows a PSA level of 18 ng/mL. Upon examination, you noticed the prostate is enlarged with an increase in blood flow and some hyperechoic nodules. What stage of prostate cancer could this indicate?
T2
27
A man presents to the ER complaining of pain in his scrotum and penis. He also noted that he has had increased frequency to urinate. When asking him how long he has been experiencing the pain and urinary frequency, he states that he has had recurrent episodes over the course of several months. Upon sonographic examination of his prostate, you visualize complex focal masses with calcifications. You also note that the peripheral zone has a heterogeneous appearance. What is the most likely diagnosis?
Chronic prostatitis
28
What shape does the hyperechoic pattern of calculi in the most caudal portion of the transitional zone (TZ) resemble?
Eiffel Tower
29
A 73 year old male comes in for an ultrasound due to some recent urinary problems such as dribbling and difficulty starting a stream. Sonographic examination demonstrates two echogenic nodules in the transitional zone, a compressed central and peripheral zone, along with hydronephrosis. What is the most likely diagnosis?
Benign prostatic hypertrophy (BPH)
30
A 50 year old male presents with pain, fever, and rectal tenderness. They order an ultrasound and the peripheral zone of the prostate has a hyperechoic appearance. What is the most likely diagnosis?
Prostatitis
31
This zone of the prostate comprises 5 to 10% of the glandular tissue, and consists of two small lobules found lateral to the prox urethral segment. What prostate zone is this?
Transitional zone
32
Where do the ejaculatory duct, vas deferens, epididymides, and seminal vesicles originate from?
Wolffian ducts
33
A small pouch found near the opening of the prostatic ducts:
Prostatic utricle
34
Where do the Müllerian ducts fuse?
In the midline caudally
35
What do the Müllerian ducts give rise to?
Prostatic utricle
36
The prostate lies anterior to..
The rectal ampulla
37
Describe the shape of the normal prostate gland
Oval or chestnut
38
Describe the anatomical location of the prostate
Retroperitoneal
39
What are the two main portions of the prostate along with their locations?
Base (superior) Apex (inferior)
40
What arteries supply the prostate?
Prostatitcovesical arteries arising from the internal iliac arteries
41
Describe the flow of blood in the prostate beginning with the internal iliac arteries:
Internal iliac arteries Prostatitcovesical arteries Split into prostate artery Split into the urethral and capsular arteries and inferior vesical arteries Bladder base, seminal vesicles, and ureter
42
T/F The normal prostate displays hypervascularity
False; Moderately vascular
43
The prostate has ___ lobes and ___ zones
5 lobes 4 zones (more commonly used)
44
What are the lobes of the prostate?
Anterior Middle Posterior Two lateral lobes
45
The urethra is the primary anatomic reference point; what two portions does it divide the prostate gland into?
Anterior Fibromuscular portion Posterior Glandular portion
46
What accounts for two-thirds of the prostate and contains four zones?
Glandular tissue
47
List the four zones of glandular tissue:
1 Peripheral zone (PZ) 2 Central zone (CZ) 3 Transitional zone (TZ) 4 Periurethral glandular tissue (PG)
48
What zone occupies the posterior, lateral, and apica portions of the gland?
Peripheral zone
49
What is the largest zone?
Peripheral
50
Verumontanum
Ejaculatory duct entering urethra A mound of the posterior wall of the prostatic urethra representing mid prostatic urethra and apex
51
Where do the ducts of the peripheral zone enter the distal urethra?
Between the verumontanum
52
Describe the sonographic appearance of the normal peripheral zone
Homogeneous, isoechoic echotexture, seporated from the central zone by the surgical capsule
53
Hyperechoic band separating central zone from peripheral zone:
Surgical capsule
54
What zone comprises 25% of glandular tissue and is rarely affected by disease?
Central zone (CZ)
55
Which zone is located at the base of the prostate like a midline wedge between the peripheral and transition zones?
Central zone (CZ)
56
Where do the vas deferens and Seminal vesicles ducts enter ?
The central zone
57
Where do the the ejaculatory ducts pass through before reaching verumontanum ?
Central zone
58
T/F The central zone is more hypoechoic than the peripheral zone
False The central zone is more hyperechoic than the peripheral zone
59
Which zone comprises 5-10% of the glandular tissue and the periurethral glands?
Transitional zone (TZ)
60
What zone consists of two small lobules found lateral to the prox urethral segment
Transitional zone (TZ)
61
The transitional zone follows the long axis of the urethra toward the…
Bladder neck
62
The most causal segment of the of the TZ is located…
At the verumontanum
63
What zone does BPH originate in?
Transitional zone
64
20% of cancer originate…
In the transitional zone
65
BPH may cause the TZ to appear more…
Hypoechoic
66
T/F Transitional zone and peripheral zone have the same echogenicity
True Transitional zone is isoechoic to peripheral zone
67
What is commonly seen in the TZ?
May see hyperechoic pattern of calculi thst resembles the Eiffel Tower in the most caudal portion
68
Small area of tissue that lines the proximal prostatic urethra
Periurethral glandular zone (PG)
69
What are the paired structures which serve as reservoirs for seminal fluid?
The seminal vesicles
70
What do Seminal vesicles appear as when full?
will appear as a large ovoid shaped cystic structures often seen with some low level echoes within the anechoic fluid (Hazy appearance)
71
When are seminal vesicles considered empty?
Post sexual activity
72
What do the seminal vesicles appear as when empty?
Curvilinear, hypoechoic structures that spread out laterally (wings)
73
Prostate is inferior to…
Inferior to seminal vesicles and urinary bladder
74
Prostate is posterior to…
Space of retzius
75
Describe the space of retzius
Retropubic space between the symphasis pubis and bladder
76
The prostate is anterior to…
Denonvilliers fasia
77
What separates the prostate and rectum and serves as an important landmark for radical prostatectomy?
Denonvilliers fasia
78
What is secreted by the prostate and provides a mode of fluid transport for sperm?
Alkaline fluid
79
What produced the majority of ejaculatory fluid volume?
Prostate
80
What is produced by the glandular tissue?
Prostate specific antigen (PSA)
81
Testosterone and dihydrotestosterone regulate…
Prostate growth and function
82
The most accurate method to calculate prostate function is by:
Calculating the prostate specific antigen density (PSAD)
83
Formula for PSAD:
Divide PSA by prostate volume. Volume is calculated by height x width x length x 0.52
84
Normal PSAD volume is:
Less than 20 grams
85
A protein produced by the cells of the prostate with a normal range of 0 — 0.4 ng/mL in blood
PSA Prostate specific antigen
86
What would be considered a strong likelihood for the presence of cancer in terms of PSA?
Greater than 20 ng/mL
87
What percentage of increased PSA in one year is considered abnormal?
20%
88
An increase of _______ ng/mL in one year is an indication of prostatic cancer?
0.75 ng/mL
89
What are the two PSA assays?
Monoclonal and Polyclonal
90
PSA assay pertaining to a protein from a single clone of cells is termed
Monoclonal
91
What is a normal monoclonal value?
4 ng/mL
92
How do you determine the serum prostate specific antigen (SPSA?)
Multiply PSA by 0.12
93
If the SPSA (serum prostate specific antigen) is higher than PPSA (predicted prostate specific antigen), the probability of cancer or prostatitis is greater than…
50%
94
PSA assay pertaining to proteins from more than a single clone of cells
Polyclonal
95
Normal range for polyclonal
0.2 — 2.5 ng/mL
96
Common urinary symptoms that indicate examination:
Frequency Nocturia (due to incomplete emptying ad rapid refilling of the urinary bladder) Dysuria Decreased force of urinary stream Terminal dripple
97
What is the best patient position for a TRUS exam?
LLD with knees flexed towards the chest
98
What should always be performed prior to a TRUS exam?
A digital rectal exam (DRE) This is to ensure there are no rectal abnormalities.
99
Transducer for transabdominal approach
3–5 MHz
100
Transducer for TRUS approach
5-8 MHz
101
Where should the near field / far field be located TRUS?
The image needs to be inverted and then the near field is at the bottom of your image and far field is at the top
102
During a TRUS exam in the sagittal plane, the base of the gland will be located:
To the left of your image
103
During a TRUS exam in the sagittal plane, the apex of the gland will be located:
To the right of your image
104
T/F TRV or axial right and left orientation are flipped for TRUS
False The right and left stay the same, only top and bottom flip
105
During a TRUS exam, the rectal wall can be seen in:
The near field
106
During a TRUS exam, the bladder will be seen in the:
Far field
107
During a TRUS exam, the prostate can be visualized
Between the rectal wall and bladder
108
During a TRUS exam, you need to fan ______________ to find seminal vesicles
Laterally
109
What is the sonographic appearance of a normal prostate during a TRUS exam?
Hypoechoic Symmetrical size and shape Bow-tie appearance
110
The vas deferans can be seen
Between the seminal vesicles
111
Thin-Waller tubular structure entering the base of the prostate in sagittal:
Vas deferans
112
Doughnut shaped structure in Trv during a TRUS exam:
Vas deferans
113
Sonographic appearance of the base of the prostate:
Half moon shaped Homogeneous texture Isoechoic
114
What is see within the center of the prostate gland at the level of the verumtanum?
Periurethral vessels
115
What is seen on the outer perimeter of the prostate gland?
Capsular arteries
116
What is the best disinfectant for the probe after a TRUS exam?
Washed and soaked in antiseptic
117
What is the most commonly used method to determine the size of the prostate?
Prostatic volume 1.57(W x P X L)
118
What is considered a normal prostate volume?
Less than 20 g
119
A small percentage of this pathology starts in the periurethral glandular tissue, but it usually occurs in the transitional zone
benign prostatic hyperplasia
120
What is the surgical procedure done to relieve symptoms of BPH?
TURP (transurethral resection)
121
What might cause a large surgical defect that sonographically appears as an anechoic space in the areas of the prostatic urethra In the center of the prostate?
TURP (transurethral resection)
122
What is considered an enlarged gland in older men?
40 g
123
Name that pathology! Symptoms: -enlarged gland -hypoechoic inner region compared to the peripheral region -may have echogenic nodule in the transitional zone -The central and peripheral zone may be compressed -Calcification and cystic changes may be seen -thickened bladder wall -distended bladder -possible hydronephrosis, hydroureters -asymmetric enlargement which should be evaluated for malignant change.
Benign prostatic hyperplasia (BPH)
124
What are the three primary types of BPH?
Homogeneous stromal hyperplasia Glandular hyperplasia Mixed hyperplasia
125
What type of BPH appears Hypoechoic?
Homogeneus stromal hyperplasia
126
What type of BPH may be hypoechoic or hyperechoic based on cystic changes and gland size?
Glandular hyperplasia
127
The most common type of BPH that appears heterogeneous sonographically.
mixed stronal and glandular hyperplasia
128
Acute inflammation usually seen in the peripheral zone
Acute prostatitis
129
What are the clinical symptoms for prostatitis?
Pain Rectal and prostate tenderness Fever
130
Complications that may occur with prostatitis:
Abscess (Anechoic mass with or without echoes)
131
What is the sonographic appearance for prostatitis?
Usually appears normal Diffuse Hyperechoic appearance of peripheral zone Hypervascularity Can mimic carcinoma in cases of focal infections Hypoechoic mass
132
Recurrent episodes of chronic acute inflammation:
Chronic prostatitis
133
Clinical symptoms for chronic inflammation:
Vary Pain in scrotum, penis, thighs Dysuria Urgency to urinate Infertility due to scarring or bloackage of the ejaculatory ducts
134
Name that pathology! Sonographic appearance: -focal masses of varying echogenicity -calcification -capsular thickening and/or irregularity -hypoechoic halo in periurethral area -Heterogeneous appearance of the peripheral zone due to scarring and necrosis -diffuse or focal hyperemic flow
Chronic prostatitis
135
What is the fifth leading cause of death in men over 45 years of age and the highest leading cause of death in men over the age of 75?
Prostate carcinoma
136
What prostate pathology is most common in African American men and those with a family history?
Prostate carcinoma
137
T/F Prostate carcinoma will have a decreased PSA
False Increased PSA
138
What percent of prostate carcinoma is located in the peripheral vs transitional vs central zone?
70% peripheral 20% transitional 10% central
139
Name that pathology! Sonographic appearance: -small nodules usually hyperechoic and located in peripheral zone -75% occur within 3mm—6mm of the apex -Isoechoic, hyperechoic, or mixed nodules -Enlarged, asymmetric prostate -capsular bulging -thickened bladder wall -distended bladder -bilateral hydroureters and hydronephrosis -loss of smooth contour in the area of the lesion -increased flow and low resistive index in peripheral vessels of cancerous lesion.
Prostate carcinoma
140
What stage of prostate cancer is described as the following? -Not palpable -Not usually sonographically apparent -confined to prostate
Stage T1
141
What stage of prostate cancer is described as the following? -palpable by digital rectal exam -confined to prostate
stage T2
142
What stage of prostate cancer is described as the following? -local extension outsie of prostate into seminal vesicles or periprostatic soft tissue -no other metastatic evidence
Stage T3
143
What stage of prostate cancer is described as the following? -Tumor extension seen on adjacent structures -metastatic evidence
Stage T4
144
What is a common use for transrectal sonography involding ruling out the obstruction of the ejaculatory ducts by scarring, calcifications, or compression from prostatic lesions?
Male infertility exam
145
Obstructing cysts of the seminal vesicles, ejaculatory ducts, or prostate as well as ductal obstruction due to calculi is an indicator for…
male infertility
146
occlusion or absence of vas deferens is an indictor for…
male infertility
147
Direct placement of multiple radioactive seeds
brachytherapy (radiotherapy guidance)
148
freezing the prostate with thermal probes
Cryotherapy (radiotherapy guidance)
149
What are three reasons aside from pathological diagnosis to give a TRUS?
male infertility, prostate biopsy, radiotherapy guidance
150
A 50 year old male presents with recurrent pelvic discomfort, dysuria, pain in the scrotum and thighs, and an increased urinary frequency. He mentions occasional painful ejaculation. His doctor is concerned about chronic prostatitis. A TRUS is ordered to evaluate the prostate. What is the most consistent sonographic finding with chronic prostatitis?
Hypoechoic halo in the periurethral area
151
John, a 50 year old, presents with the following symptoms: dysuria, urgency to urinate, increased frequency to urinate. While performing a TRUS, you find the following image (calcifications) What is the most likely diagnosis?
Chronic prostatitis
152
In what zone of prostate do 20% of cancers originate?
Transitional zone
153
During a transrectal ultrasound, a round, well-defined, anechoic structure is seen with the prostate. It has smooth walls and shows posterior acoustic enhancement. The patient is asymptomatic. What is the most likely diagnosis?
Prostatic cyst
154
What ultrasound finding is most commonly seen in benign prostatic hyperplasia (BPH?)
Enlarged central gland with heterogeneous echotexture
155
What is the largest zone of glandular tissue in the prostate?
Peripheral zone
156
You have a patient come in for a follow up TRUS exam, they have a history of benign prostatic hypertrophy (BPH). While scanning, you see an asymmetrical anechoic structure within the prostate. What would be the reason for the images below (anechoic)
TURP (transurethral resection)