Proteins Flashcards

(27 cards)

1
Q

protein

A

proteios=first in rank (Greek), macromolecule built up by amino acids

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2
Q

structure of proteins

A

3D, spatial form of the protein chain stabilized by weak interactions (electrostatic, van der Waals)


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3
Q

primary structure of proteins

A

sequence of amino acids building up the molecule

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4
Q

secondary structure of proteins

A

formation of regular structures (α-helix, β-sheet) in the peptide chain stabilized by H-bonds


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5
Q

quaternary structure of proteins

A

spatial arrangement of peptide chains and non-peptide components of a protein


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6
Q

conformational change

A

transient, reversible change in the spatial structure of a protein molecule

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7
Q

globulin

A

protein molecule that has a spherical tertiary structure (e.g. hemoglobin, immunoglobulin)

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8
Q

myoglobin

A

iron-containing oxygen-binding protein molecule in the muscles resembling hemoglobin


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9
Q

denaturation

A

usually irreversible change in the conformation of protein molecules


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10
Q

antibody (and immunoglobulin)

A

protein molecule produced by the lymphocytes that can specifically bind to antigens


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11
Q

memory cell

A

lymphocyte specialized for the long-term storage of the code to synthesize an antibody

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12
Q

antigen

A

usually a large molecule or a smaller part of it that induces immunological response in the target organism

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13
Q

autoimmune disease

A

erroneous immune response of an organism against its own proteins or macromolecules


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14
Q

complement system

A

protein molecules responsible for the elimination of the antigen-antibody complex

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15
Q

effector protein

A

protein transmitting the effect of G-protein activation in the cell


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16
Q

G-protein

A

GTP-binding protein at the inner surface of plasma membranes; plays a critical role in signal transduction

17
Q

glycoprotein

A

a protein containing carbohydrate groups

18
Q

intrinsic (integral) protein

A

membrane protein spanning

19
Q

peripheral (extrinsic) protein

A

protein associated to the external or internal surface of the cell membrane
the membrane from one surface to the other

20
Q

lipoprotein

A

protein molecule containing lipid groups


21
Q

peptide

A

short protein molecule


22
Q

contractility

A

ability for shortening

23
Q

actin and myosin

A

proteins responsible for the muscle contraction

24
Q

filament

A

thin fiber made up of proteins; sliding of actin and myosin filaments on each other explains muscle contraction.

25
collagen
protein, main component of the collagen fibers
26
albumin
largest protein fraction in the blood plasma, mainly responsible for the colloid osmotic pressure of the plasma

27
fibrinogen
protein component of the blood plasma; its polymerization to fibrin is the most important step of blood coagulation