PRRs Flashcards

1
Q

TRIACIL LIPOPÉPTIDO - MICOBACTERIAS Y BACTERIAS GRAM NEG

A

TLR1

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2
Q

PEPTIDOGLICANOS - BACTERIAS GRAM POS

A

TLR2

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3
Q

RNA VIRAL DE DOBLE HEBRA

A

TLR3

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4
Q

LIPOPOLISACÁRIDOS - BACT GRAM NEG

A

TLR4

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5
Q

FLAGELINA (BACTERIAS)

A

TLR5

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6
Q

DIACIL LIPOPÉPTIDO - MICOBACTERIAS Y BACTERIAS GRAM POS

A

TLR6

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7
Q

RNA DE UNA SOLA HEBRA VIRAL

A

TLR 7 Y 8

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8
Q

ADN BACTERIANO

A

TLR9

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9
Q

NO SE CONOCE PAMP

A

TLR10, TLR12

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10
Q

NOS AYUDA A IDENTIFICAR BACTERIAS UROPATÓGENAS, PERO NO SE CONOCE EL PAMP Y TOXOPLASMA QUE SU PAMP ES TROFILINA

A

TLR11

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11
Q

NO SE CONOCE PAMP PERO RECONOCE VIRUS DE LA ESTOMATITIS VESICULAR

A

TLR13

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12
Q

Peptidoglicanos bacterianos

A

NLR NOD 1 Y 2

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13
Q

Toxinas

A

NLR NALP1

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14
Q

RNA bacteriano, cristales de urato monosódico (causante de gota).

A

NLR NALP3

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15
Q

Flagelina

A

NLR NALP5 E IPAF

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16
Q

Funcionan como PAMP para NALP3, RECONOCEN DAMPS

A

CRISTALES DE URATO Y PROTEÍNA C REACTIVA

17
Q

TODOS LOS PRRs Van a estar pegados a una membrana, no hay PRRs solubles ni libres

A

VERDADERO

18
Q

SE PUEDE ACTIVAR POR PRESENCIA DE DAMPS Y POR LA LUZ UV, Formado por NLRP3 + ASC (molécula adaptadora) + CASPASA-1. Este complejo molecular activa a 2 citocinas proinflamatorias → IL-1 e IL-8. SU FUNCIÓN ES ACTIVARLAS:

A

INFLAMASOMA