PSA

Question 1

What should you check before prescribing metformin?

Answer 1

Renal Function

Question 2

Which antibiotics may lower seizure threshold in epilepsy?

Answer 2

Quinolones (ie. Ciprofloxacin)

Question 3

What is the dose of adrenaline in cardiac arrest?

Answer 3

1:1000 10ml

Question 4

Which CCB most exaggerates heart failure?

Answer 4

Verapamil

Question 5

Can doxycycline be used in pregnancy?

Answer 5

No

Question 6

How is cocaine overdose managed?

Answer 6

Benzos

Question 7

Which complication is most commonly associated with aminoglycosides such as gentamicin?

Answer 7

Nephrotoxicity

Question 8

Which antibiotics may cause long QT?

Answer 8

Macrolides eg Clarithromycin

Question 9

Which drugs should be avoided in renal failure?

Answer 9

NSAID
Metformin
Lithium
Tetracycline, Nitrofurantoin

Question 10

Which drugs can treat motion sickness

Answer 10

Hyoscine
Cyclizine
Promethazine

Question 11

When would you give IV sodium bicarbonate in TCA overdose?

Answer 11

pH <7.1
QRS >160 ms
Arrhythmias
Hypotension

Question 12

In which patient group is diclofenac contraindicated?

Answer 12

Those with cardiovascular disease

Question 13

Which antibiotics are contraindicated in those with G6PD Deficiency (Heinz bodies on smear)

Answer 13

Quinolones (Ciprofloxacin)

Question 14

How is heparin monitored in patients with renal impairment?

Answer 14

Anti Factor Xa levels

Question 15

How is organophosphate poisoning managed?

Answer 15

Atropine

Question 16

What are the most common side effects of calcium channel blockers?

Answer 16

Headache, flushing, ankle oedema

Question 17

Which drugs can cause hypomagnesaemia?

Answer 17

PPIs
Diuretics

Question 18

Which drug can be used to manage tremor in drug-induced parkinsonism?

Answer 18

Procyclidine

Question 19

What would be used to alleviate pain in cases of raised ICP due to brain cancer?

Answer 19

Dexamethasone

Question 20

Which cvs drug can worsen psoriasis?

Answer 20

Beta Blockers

Question 21

Which class of drugs may worsen Parkinsonism?

Answer 21

Antipsychotics (Oral lorazepam)

Question 22

What should be started in T2DM in a patient with CVD?

Answer 22

Metformin and an SGLT2 Inhibitor as first line

Question 23

Which important side effect is most important to counsel patients of when using clindamycin?

Answer 23

C.Dif risk

Question 24

How is acute relapse managed in MS?

Answer 24

Methylprednisolone (IV or Oral)

Question 25

What would you give for secondary prevention following stroke if Diclofenac is contraindicated?

Answer 25

Aspirin and Dipyridamole

Question 26

Duloxetine and renal failure?

Answer 26

Contraindicated GFR under 30

Question 26

Duloxetine and renal failure?

Answer 26

Contraindicated GFR under 30

Question 27

45yo M. HTN. T2DM. Renal Artery Stenosis. Antihypertensive?

Answer 27

CCB. ACEi contraindicated in renovascular disease

Question 28

Which macrolide should be used in pregnancy?

Answer 28

Erythromycin

Question 29

What is an importnt side effect of metoclopramide to counsel male patients on?

Answer 29

Galactorrhoea

Question 30

In whom is adenosine contraindicated?

Answer 30

Asthmatics due to bronchospasm

Question 31

Name a contraindication to triptan use in migraine prophylaxis.

Answer 31

CVD

Question 32

When is pioglitazone contraindicated?

Answer 32

Heart Failure

Question 33

What are the first two lines of MRSA management?

Answer 33

Vancomycin -> Linezolid

Question 34

Which tests must. be performed before starting treatment for TB?

Answer 34

U&Es, LFTs, FBC, Vision Testing

Question 35

What is an alternative aldosterone antagonist if spironolactone is not tolerated in a patient with chronic congestive heart failure?

Answer 35

Eplerenone

Question 36

What is the first line treatment for CML?

Answer 36

Imatinib - Tyrosine Kinase Inhibitor

Question 37

Gonorrhoea management if patient doesn't like needles?

Answer 37

Oral Cefixime Oral Azithromycin

Question 38

How would you treat chlamydia in pregnancy?

Answer 38

Azithromycin, erythromycin, amoxicillin

Question 39

Which drugs most commonly cause angioedema?

Answer 39

ACEi

Question 40

What is an important side effect of the induction agent etomidate?

Answer 40

Adrenal Suppression

Question 41

What are the main side effects of tamsulosin?

Answer 41

Dizziness and Postural hypotension

Question 42

When is Pioglitazone contraindicated?

Answer 42

Bladder Cancer

Question 43

When should calcium/iron supplements be taken in a patient on thyroxine replacement?

Answer 43

At least 4 hours after levothyroxine dose

Question 44

Which tb med causes orange tears/urine?

Answer 44

Rifampicin

Question 45

Which dmard can patients allergic to aspirin also be sensitive to?

Answer 45

Sulfasalazine

Question 46

What is a key complication of rapid vancomycin infusion?

Answer 46

Red Man Syndrome

Question 47

What should be prescribed for a diabetic patient with urine ACR over 3?

Answer 47

ACEi or ARB for renal protection

Question 48

What is the first line treatment for acute flares of acute intermittent porphyria?

Answer 48

Haem Arginate

Question 49

What should you take a statin?

Answer 49

Last thing at night

Question 50

What is the most common side effect of isotretinoin?

Answer 50

Dry skin

Question 51

Name a severe ocular side effect of hydroxychloroquine

Answer 51

Bull's Eye Retinopathy