PSA

Question 1

Drugs which increase risk of falls

Answer 1

• benzos
• antidepressants
• MAOI
• most antipsychotic s
• opiates
• anti-hypertensives (particualrly diuretics and alpha-blockers)

Question 2

Drugs which increase the risk of fractures

Answer 2

PPI
steroids
GnRH agonists (buserelin, goserelin)

Question 3

Which two T2DM medications can result in pancreatits

Answer 3

• DDP4i (sitagliptin) and GLP1 analogue (exenatide)

Question 4

THiazolidinedione SE

Answer 4

oedema
HF
post menopausal OP
bladder cancer
weight gain

Question 4

DDP4i SE

Answer 4

pancreatitis
nasopharyngitis

Question 5

a-glucodiase inhibitor (acarbose) SE

Answer 5

bloating
flatulence
diarrhoea

Question 6

GLP1 analogue SE

Answer 6

-nausea
-diarrhoea
- pancreatitis

Question 7

which diabetic medication can result in weight gain

Answer 7

sulphonureas, thiazolidinedione, insulin

Question 8

Drugs to stop in AKI

Answer 8

Stop the DAMN drugs

diuretics
acei/arb
metformin
nsaids

Question 9

Lithium - excretion reduced by

Answer 9

ACEi, thiazides, NSAIDS

Question 10

Liver injury and drugs - ALT : ALP 2-5

Answer 10

mixed picture
Phenytoin
Sulphonamides
Carbamazepine

Question 11

Liver injury and drugs - ALT : ALP <2

Answer 11

cholestatic picture
Co-amoxiclav
Erythromycin
Chlorpromazine
Hormonal contraceptio

Question 12

Liver injury and drugs - ALT : ALP >5

Answer 12

hepatocellular picture
Paracetamol
NSAIDs
Statins
Amiodarone

Question 13

NSAID SE

Answer 13

Stomach ulcers
ARF
Bronchoconstriction - asthma
Peripheral oedema

Question 14

Thiazide SE

Answer 14

Hypokalaemia, dyslipidaemia (inhibits lipoprotein lipase), gout, hyponatraemia, hypercalcaemia

Question 15

when is the best time to take drugs

Answer 15

steroids - morning
bet blockers - morning
diuretics - morning

anti-hypertensives - evening

Question 16

Beta blocker SE

Answer 16

bronchoconstriction
bradycardia

Question 17

interaction with levothyroxine

Answer 17

iron and calcium

leave at least a 4 hour gap

Question 18

how is moderate UC defined

Answer 18

In a mild-moderate flare of ulcerative colitis extending past the left-sided colon, oral aminosalicylates should be added to rectal aminosalicylates, as enemas only reach so far

Question 19

monitoring for anticoagulants

Answer 19

LMWH – anti-factor Xa
Unfractioned heparin – aPTT
NOACs – monitor clinically
Warfarin – INR

Question 20

best anti emetic for Parkinsons

Answer 20

domperidone

Question 21

most likely to cause hyperglycaemia

Answer 21

steroids
antipsychotics
thiazides
beta blockers
tacrolimus

Question 22

most likely to cause diarrhoea

Answer 22

antibiotics
colchine
metformin
PPI
antacids that contain magnesium
laxative

Question 23

most likely to cause urine incontinence

Answer 23

alpha-blockers
diuretics
anticholinesterase inhibitors
cloazapine

Question 24

most likely to cause high cholesterol

Answer 24

steroids thiazides

Question 25

most likely to cause hypertension

Answer 25

NSAID steroid oral contraception mirabegron

Question 26

causes of hypokalaemia

Answer 26

loop diuretics thaizides steroids salbutamol

Question 27

cause of hyperkalaemia

Answer 27

K+ sparing diuretics ACEi ARBs unfractionated or LWMH blood transfusion

Question 28

cause of hyponatraemia

Answer 28

SSRI TCA carbamazepine opiates PPI

Question 29

most likely to worsen myasthenia gravis

Answer 29

antibiotics beta blockers local anaethetic sedating drugs