PSA

Question 1

Features of Digoxin toxicity

Answer 1

A. Confusion, nausea, visual halos, and arrhythmia (and down sloping ST in all leads)

Question 2

Features of Lithium toxicity

Answer 2

A. Early: tremor
Intermediate: tiredness
Late: arrhythmia, seizures, coma, renal failure, diabetes insipidus, thyroid

Question 3

Features of Phenytoin toxicity

Answer 3

A. (Enzyme inducer)

Gum hypertrophy, ataxia, nystagmus, peripheral neuropathy and teratogenicity

Question 4

Features of Gentamicin and Vancomycin toxicity

Answer 4

A. Ototoxicity and nephrotoxicity

Question 5

Mx of warfarin in major bleed

Answer 5

1. Stop warfarin
2. Give 5-10mg IV vitamin K
3. Give prothrombin complex

Question 6

Mx of warfarin with raised INR

Answer 6

<5 - reduce dose
5-8 - omit warfarin for 2 days then reduce dose
>8 - omit warfarin and give 5mg oral vitamin K

Question 7

Causes of SIADH

Answer 7

SCLC 
Infection 
Abscess 
Drugs (antipsychotics, carbamazepine and carbimazole) 
Head injury