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RUSVM Pharmacology Summer 2017 > PSNS Drugs > Flashcards

Flashcards in PSNS Drugs Deck (24):
1

Which drug is a Direct acting parasympathomimetic?
A. Neostigmine
B. Edrophonium
C. Bethanoechol
D. Pyridostigmine

C. Bethanechol

2

A cat in your clinic requires cataract surgery, therefore a neuromuscular blocker drug will be administered. Once the surgery is over which drug should you draw up to reverse the effects of the NMB drug?
A. Neostigmine
B. Edrophonium
C. Bethanoechol
D. Pyridostigmine

A. Neostigmine

3

What is the mechanism of action of Neostigmine?
A. Direct acting parasympathomimetic
B. Indirect acting parasympathomimetic
C. Direct acting parasympatholytic
D. Indirect acting parasympatholytic

B. Indirect acting parasympathomimetic

4

A cat comes into your clinic and is screaming because it is unable to urinate. You run some tests to make sure the cat does not have a urinary tract obstruction. The cat has no obstruction so you decide it is safe to administer which of the following drugs?
A. Neostigmine
B. Edrophonium
C. Bethanoechol
D. Pyridostigmine

C. Bethanoechol

5

What is the mechanism of action of Pyridostigmine?
A. Direct acting parasympathomimetic
B. Indirect acting parasympathomimetic
C. Direct acting parasympatholytic
D. Indirect acting parasympatholytic

B. Indirect acting parasympathomimetic

6

Which of the following drugs is a competitive antagonist of neuromuscular blockers?
A. Neostigmine
B. Edrophonium
C. Bethanoechol
D. Pyridostigmine

A. Neostigmine

7

A dog comes into your clinic with a neuromuscular disease that effects the neuromuscular junction, causing nicotinic receptors to not work normally, the disease is known as myasthenia graves. Which drug would be most appropriate treatment of choice for this disease?
A. Neostigmine
B. Edrophonium
C. Bethanoechol
D. Pyridostigmine

D. Pyridostigmine

8

Neostigmine's onset and duration of action is:
A. relatively short onset, very short acting
B. relatively short onset, very long acting
C. relatively long onset, very short acting
D. relatively long onset, very long acting

A. relatively short onset, very short acting

9

Pyridostigmine's onset and duration of action is:
A. relatively short onset ( ~1 hour), short acting (~30min-1 hour)
B. relatively short onset (~1 hour), long acting (~8-12 hours)
C. relatively long onset (~2 hours), short acting (~30min-1 hour)
D. relatively long onset (~2 hours), long acting (~8-12 hours)

B. relatively short onset (~1 hour), long acting (~8-12 hours)

10

Edrophonium's onset and duration of action is:
A. Very slow onset, very short duration
B. Very fast onset, very short duration
C. Very slow onset, very long duration
D. Very fast onset, very long duration

B. Very fast onset, very short duration

11

A dog comes into your clinic and has muscle weakness. You suspect the dog may have myasthenia graves disease. You decide to do a Tension test while waiting for conclusive lab result which takes about a week to get back. Which drug would be most appropriate to use perform this test (1) ? If a positive result is seen while using this drug, and you get conclusive lab tests back confirming myasthenia graves disease, which drug would you use as the treatment of choice for this disease (2) ?
A. 1. Neostigmine; 2. Edrophonium
B. 1. Edrophonium; 2. Neostigmine
C. 1. Pyridostigmine; 2. Edrophonium
D. 1. Edrophonium; 2. Pyridostigmine
E. 1. Edrophonium; 2. Edrophonium

D. 1. Edrophonium; 2. Pyridostigmine

12

Atropine Sulfate has what mechanism of action?
A. Direct acting parasympathomimetic
B. Indirect acting parasympathomimetic
C. Direct acting parasympatholytic
D. Indirect acting parasympatholytic

C. Direct acting parasympatholytic

13

Glycopyrrolate has what mechanism of action?
A. Direct acting parasympathomimetic
B. Indirect acting parasympathomimetic
C. Direct acting parasympatholytic
D. Indirect acting parasympatholytic

C. Direct acting parasympatholytic

14

Oxybutynin has what mechanism of action?
A. Direct acting parasympathomimetic
B. Indirect acting parasympathomimetic
C. Direct acting parasympatholytic
D. Indirect acting parasympatholytic

C. Direct acting parasympatholytic

15

Propantheline has what mechanism of action?
A. Direct acting parasympathomimetic
B. Indirect acting parasympathomimetic
C. Direct acting parasympatholytic
D. Indirect acting parasympatholytic

C. Direct acting parasympatholytic

16

Aminopentamide has what mechanism of action?
A. Direct acting parasympathomimetic
B. Indirect acting parasympathomimetic
C. Direct acting parasympatholytic
D. Indirect acting parasympatholytic

C. Direct acting parasympatholytic

17

N-Butylscopolammonium bromide has what mechanism of action?
A. Direct acting parasympathomimetic
B. Indirect acting parasympathomimetic
C. Direct acting parasympatholytic
D. Indirect acting parasympatholytic

C. Direct acting parasympatholytic

18

Which of the following drugs is used to treat bradycardia and cardiac arrest, that can cross the blood brain barrier?
A. Oxybutynin
B. Atropine Sulfate
C. Propantheline
D. Glycopyrrolate

B. Atropine Sulfate

19

Which of the following is a contraindication for the use of atropine?
A. Sinus bradycardia
B. 2nd degree AV block
C. Closed- angle glaucoma
D. Nausea

C. Closed- angle glaucoma

20

Compared to atropine, which of the following is true about glycopyrrolate?
A. Lasts longer than atropine
B. Crosses BBB
C. Antagonizes primarily nicotinic receptors
D. Does not treat bradycardia

A. Lasts longer than atropine

21

Which of the following drugs crosses the blood brain barrier and has an indicated use as an urinary antispasmodic to treat detrusor muscle instability (hyperactive bladder).
A. Oxybutynin
B. Atropine Sulfate
C. Propantheline
D. Glycopyrrolate

A. Oxybutynin

22

Which of the following drugs can NOT cross the blood brain barrier and has an indicated use as an urinary antispasmodic to treat detrusor muscle instability (hyperactive bladder).
A. Oxybutynin
B. Atropine Sulfate
C. Propantheline
D. Glycopyrrolate

C. Propantheline

23

Which of the following drugs is used an antispasmodic for GI indications in dogs and cats?
A. Propanthelin
B. Aminopentamide
C. Oxybutynin
D. N- Butylscopolammonium bromide

B. Aminopentamide

24

Which of the following drugs is an antispasmodic for colic in horses?
A. Propanthelin
B. Aminopentamide
C. Oxybutynin
D. N- Butylscopolammonium bromide

D. N- Butylscopolammonium bromide