Psych Flashcards

(231 cards)

1
Q

What is Deprivation of Liberty Safeguards(DoLS)?

A

Procedure prescribed in law when it is necessary to deprive of their liberty a resident or patient who lacks capacity to consent to their care and treatment in order to keep them safe from harm.

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2
Q

What are the 3 core syx of depression

A
  • Low mood
  • Anhedonia
  • Anergia
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3
Q

Biological manifestastions of depression

A
  • Fatigue/sleep distrubance
  • Appetite/weight change
  • Low libido
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4
Q

Cognitive features depression

A
  • Memory impairment
  • Beck’s triad
    • Hoplessness
    • Worthlessness
    • Helplessness
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5
Q

Depression diagnosis criteria timeframe

A

Syx lasting at least 2 weeks

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6
Q

Depression levels of severity

A

Mild: 2 or 3 core syx + 2 others; can continue w most dialy activities

Moderate: 2 or 3 core syx + 3-4 others; difficulty with social acitivities and day to day functioning

Severe: 3 core syx + 4 or more others; major impact on daily function

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7
Q

Things to consider when diagnosing depression

A
  • Organic causes
    • FBC
    • TFT
  • Bipolar disorder
    • Previous mood elevation - (hypo)mania
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8
Q

High risk features of completing suicide attempt

A
  • Careful planning
  • Acts in anticipation
  • Precautions to prevent discovery
  • Suicide note
  • Violent method
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9
Q

Depression Ix

A
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10
Q

Depression mx

A

Bio

  • Antidepressants
    1. SSRI - sertraline, fluoxetine, citalopram, etc.
    2. SNRI - venlafaxine
    3. Augmentation therapy
      • Diff class antidepr // add lithium
    4. ECT

Psycho

  • Self help
  • CBT
  • Interpersonal therapy

Social

  • Finance
  • Relationships
  • Occupation

Mild- moderate

  • Low intensity psychological intervention
    • Guided self-help
    • Computerised CBT
    • Structured group physical activity programme
    • Group CBT
  • +/- medication
  • 2 week follow up

Moderate - severe

  • High intensity psychological intervention
    • Individualised CBT
    • Interpersonal therapy
  • Medication
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11
Q

Classes of antidepressants and examples of each

A

Selective serotoni receptor inhibitors (SSRIs)

  • Sertraline
  • Fluoxetine
  • Citalopram
  • Escitalopram

Serotonin and noradrenaline receptor inhibitors (SNRIs)

  • Venlafaxine
  • Deloxetine

Tricyclic anti-depressants (TCAs)

  • Amitriptyline
  • Notriptyline

Monoamine oxidase inhibitors (MAOis)

  • Phenelzine

Noradrenergic and specific serotonergic antidepressants (NaSSA)

  • Mirtazapine

Reversible inhibitors of monoamine oxidase type A (RIMAs)

  • Moclobemide
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12
Q

How long should pts continue antidepressants post-recovery for optimum prognosis?

A

6 months

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13
Q

SSRI side effects

A
  • GI syx
  • GI bleeding (+PPI)
  • Hyponatraemia
    • confusion, dizziness and weakness
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14
Q

How long does it take to stop an SSRI?

A

Withdraw gradually over 4 weeks

*Except fluoxetine due to its longer half life

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15
Q

SSRI discontinuation syndrome

A
  • Anxiety
  • GI symptoms
  • Electric shock sensations
  • Dizziness
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16
Q

SSRIs and pregnancy

A

Avoid unless benefits outweigh risks

  • 1st trimester - small increased risk of congenital heart defects
  • 3rd trimester - can result in persistent pulmonary hypertension of the newborn
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17
Q

Indications for Sertraline

A

Unstable angina or recent MI

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18
Q

How to swap from Fluoxetine to different SSRI?

A

Stop fluoxetine then 1 week wash out period (due to long half life) then start gradually

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19
Q

Citalopram and Escitalopram SEs

A

ventricular arrhythmias including torsade de pointes

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20
Q

Serotonin syndrome

A
  • confusion
  • agitation
  • muscle twitching
  • sweating
  • shivering
  • diarrhoea
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21
Q

SNRI SEs

A
  • Hypertension
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22
Q

TCA side effects

A
  • Overflow urinary incontinence
  • Prolonged QT on ECG
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23
Q

MAO-I Precaution

A

Avoid cheese (tyramine) –> hypertensive crisis

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24
Q

What (non-psych) drug can cause low mood?

A

Beta blockers

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25
Seasonal affective disorder
depression which occurs predominately around the winter months
26
SAD Mx
Treated the same way as depression
27
CBT explanation
CBT is a form of talking therapy based on the concept that our thoughts, emotions, and actions are interrelted, and that negative thoughts and feelings can trap you in a negative cycle. CBT aims to help us deal with problems by approaching them from a bird's eye view and breaking them down into smaller parts to change the way we think and behave
28
Normal grief reaction presentation
* Low mood * Psuedohallucinations * false sensory perception in the absence of external stimuli when the affected is aware that they are hallucinating Last up to 6months post loss
29
What is CBT used for?
* Depression * Anxiety * OCD * Eating disorders * PSTD
30
Anxiety differentials
31
What can be mistaken for anxiety?
Hyperthyroidism * Abdo pain * Palpitations * Agitated and fidgety * Difficultly sleeping * Affected concentration
32
Anxiety Ix
MSE GAD7 TFTs
33
Generalised anxiety disorder
Regular and uncontrolled (can be triggered by anything/ have no trigger) anxiety for \>= 6 months.
34
GAD Psychological presentation
* Anxiety * Fear * Impaired concentration * Irritability
35
GAD Physical presentation
* Tremors * Palpitations * Loose stools
36
GAD Mx
Bio * SSRI - sertraline specifically * higher dose than for depression * Try a 2nd SSRI or SNRI as 2nd line * Benzodiazepines * Acute use for mx bad bouts of GAD * Beta blockers * Reduce physical syx, e.g., tremor * CI in asthma/diabetes Psycho * CBT * Mindfullness * Psychoeducation Social * Advice on stress mx * Advice on coping mechanisms * e.g., drug & alcohol
37
Acute anxiety (situation) Mx
Short prescription of Benzodiazepines
38
Panic disorder (panic attacks) features
* Rapid-onset severe anxiety * Impending sense of doom * Resolves rapidly * Palpitations + tachypnoea
39
Panic disorder Mx
Bio * SSRIs Psycho * CBT Social * Psychoeducation * Breathing exercises * Support groups
40
Acute stress disorder
Acute stress reaction that occurs in the 4 weeks after a traumatic event
41
Post traumatic stress disorder
Stress reaction that develops 4 weeks following traumatic event. Symptoms present for \>1 month.
42
PTSD features
* re-experiencing: flashbacks, nightmares, repetitive and distressing intrusive images * avoidance: avoiding people, situations or circumstances resembling or associated with the event * hyperarousal: hypervigilance for threat, exaggerated startle response, sleep problems, irritability and difficulty concentrating * emotional numbing - lack of ability to experience feelings, feeling detached
43
PTSD Mx
Bio * Venlafaxine (SNRI) * or SSRI * Risperidone in severe cases *Medication is not 1st line* Psycho * Trauma-focussed CBT * Eye movement desensitisation and reprocessing (EMDR) * More severe cases Social *
44
Obsessive compulsive disorder
Recurrent obsessional thoughts or compulsive acts are developed Obsessions: thoughts/images that are distressing, unwanted and intrusive that are recognised as own thoughts Compulsions: repetitive behaviors or mental acts that a person feels driven to perform in response to an obsession
45
OCD Mx
Psycho 1. CBT including exposure and response prevention Bio 2. SSRI * Quickly increased to high dose * To continue for 12 months after pt goes into remission 3. Clomipramine or alt SSRI (if first SSRI ineffective after 12 weeks)
46
Agoraphobia
* Fear of being unable to escape to a safe place * Often end up housebound
47
Social phobia features
* Fear of being scrutinised/judged * People noticing you blush * Can tolerate large, anonymous crowds * Dislike intimate gathering
48
Type 1 vs Type 2 Bipolar disoder
**Type 1** Mania + depressive episodes **Type 2** Hypomania + depressive episodes
49
Manic episode presentation
Mania lasts for at least 7 days * Feelings of euphoria * Hallucinations and/or delusions * Predisposition to risky or reckless behaviour * Mutism * Severely manic pts
50
Mania Mx
From primary care * Urgent referral to community mental health team Psych * Olanzapine * Useful in acute mania * Long term prophylaxis for bipolar affective disorder * Clonazepam &/or Lorazepam * Fast onset of action * Tranquilising effect \*Psychological therapy not usually offered to manic pts in the acute phase
51
Manic patients risk of depressive episode in future
\>90%
52
Auditory hallucinations in Schizophrenia (3)
1. Thought echo * Hears own thoughts as if spoken aloud to them 2. 3rd person voices * People talking about them from 3rd person 3. Running commentary * Voice narrating what they are saying
53
Hypomania presentation
Typically lasting 3-4 days * Does not interefere majorly with day to day * Euphoric * Impulsive behaviour * Feels doesn't need sleep/far less sleep * Irritability * Flight of ideas
54
Hypomania mx
Low risk * Routine referral to CMHT High risk * Urgent referral to CMHT
55
Bipolar disorder Mx
* Mood stabilisers * Lithium * Alt Sodium Valproate * Address co-morbidities * 2-3x incr risk diabetes, CVD, COPD
56
Lithium monitoring
Lithium levels should be checked 12 hours post-dose * One week after starting treatment/after dose change * Weekly until the levels are stable * Once levels are stable, measure every 3 months + every 6/12: * U&Es * TFTs
57
Lithium SEs
* Hypothyroidism * Renal impairment * Preceipitation of a relapse if suddenly discontinued
58
Lithium overdose presentation
* Coarse tremors * GI disturbance * Ataxia * (white pills)
59
Lithium and pregnancy
First trimester exposure associated with Ebstein's anomaly (a serious cardiac anomaly)
60
Lithium and NSAIDs
NSAIDs can increase lithium levels in the blood resulting in an increased risk for serious adverse effects like confusion, tremor, slurred speech, and vomiting
61
Sodium Valproate SEs
* N+V * Diarrhoea * Movement disorder
62
Sodium valproate congenital risks
* cleft palate * spina bifida * Neural tube defects
63
Mx of manic/hypomanic pts on antidepressants
Consider stopping the antidepressant and start antipsychotic therapy
64
Psychosis differentials
* Acute (episode) * Transient, resolves * Organic * Drugs * Delirium * Medication * Steroids * Affective * Severe depression * Mania * Personality disorders * Schizoaffective * Schizotypal * Delusional disorder * Only have delusions
65
First episode psychosis Ix and Mx
Ix * Take a detailed history * Drug use * FHx * Perform exam and ix * Urine drug screen * Obtain collateral hx Mx * Consider section 5(2) * Refer to psych team * Commence medication * For acute agitation: Lorazepam * Antipsychotic: Atypical but NOT Clozapine * Aripiprazole 10mgOD, or Olanzapine 10mg nocte * Education & support
66
Baby blues
Tearful & emotionally labile after giving birth
67
Post natal depression screen
Ask 2 depression identification Qs (low mood & anhedonia), if +ve to one -\> **Edinburgh postnatal depression scale**
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PND Mx
* CBT * SSRI * F/U w GP * Home visits from community midwives
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Puerperal psychosis onset
Occurs in first 3 weeks post natal with acute onset
70
Puerperal psychosis presentation
* Elevated mood * Sleeping less/not sleeping * Delusions * Often grandiose
71
Schizophrenia explanation
Characterised by break down of thought process, contact with reality, and emotional responsiveness
72
Schizophrenia classification (4)
1. Paranoid (most common) * Prominent delusions & hallucinations * Dominated by sense of anxiety that something bad will happen 2. Hebephrenic * Disorganised * Chaotic mood * 'child-like' shallow & inappropriate affect 3. Catatonic * Psychomotor disturbance 4. Simple * Only negative features, e.g., social withdrawal and blunted affect
73
Schneider's first rank syx
* Auditory hallucinations * Abnormal thoughts * Delusions
74
Abnormal thoughts in Schizophrenia (3)
* Thought insertion * Thoughts have been inserted into their brain * Thought withdrawal * Thoughts are being stolen from them * Thought broadcasting * Other people can see/hear what they are thinking
75
Definition of delusion
False, fixed belief held despite conflicting evidence.
76
Development of Schizophrenia
Prodrome -\> Acute phase -\> Chronic phase Prodrome * Social withdrawal * Loss of interest in work and relationships Acute phase * Delusions * Hallucinations * Thought interference Chronic phase * Apathy * Blunted affect * Social withdrawal * Anhedonia * Poverty of thought
77
Prevalence of schizophrenia in general population
1%
78
Risk of schizophrenia in 1) child (if 1 parent has it), 2) twin
1) 10% 2) 50%
79
Schizophrenia RFs
FHx * monozygotic twin has schizophrenia = 50% * parent has schizophrenia = 10-15% * sibling has schizophrenia = 10% * no relatives with schizophrenia = 1% Others * Black Caribbean ethnicity - RR 5.4 * Migration - RR 2.9 * Urban environment- RR 2.4 * Cannabis use - RR 1.4
80
Schizophrenia Mx
81
Schizophrenia mx
Bio * Antipsychotics Psycho * CBT * Family therapy Social * Social skills training * Education * Benefits * Housing
82
Treatment resistant Schizophrenia
Failure to respond to 2 or more antipsychotics, at least 1 of which is atypical. Each given at therapeutic dose for at least 6 weeks.
83
Treatment resistant Schizophrenia Mx
Clozapine * Weekly blood tests * Risk of **agranulocytosis** * ​Decreased leukocytes * Counsel about taking infyx syx seriously \*reduces seizure threshold
84
What is prodromal schizophrenia?
earliest stage of schizophrenia (not experience by everyone)
85
Features of prodromal schizophrenia
* Nervousness * Anxiety * Depression * Difficulty concentrating * Excessive worrying
86
Typical antipsychotic mechanism
Dopamine antagonist
87
Typical antipsychotic SEs
Extra pyrimidal side effects *(mimics parkinsons)* * Acute dystonia * suddenly v painful contractions of parts of body * oculogyric crisis - deviation of eyes and repeated blinking * *Procyclidine* helps treat ^ * Tardive dyskinesia * Often develops with long term use * Lip smacking, sticking tongue out, difficulty swallowing, excessive blinking * Parkinsonism * Akathisia * restlessness
88
Typical antipsychotics examples
* Haloperidol * Chlorpromazine * Zuclopenthixol decanoate
89
Atypical antipsychotics examples
* Olanzapine * Quetiapine * Clozapine * Risperidone * Aripiprazole
90
Atypical antipsychotics mechanism
Affect dopamine, serotonin, histamine and adrenergic receptors
91
Atypical antipsychotic SEs
Metabolic * Weight gain * Dyslipidaemia * Hypercholesterolaemia * Hyperprolactinaemia
92
Missed Clozapine
If missed for \>48 hours, dose will need to be retitrated again slowly ## Footnote *Starting Clozapine after a break of \>48 hours,can make side effects worse, such as blood pressure changes, drowsiness and dizziness*
93
Adjusting Clozapine dosage
Reduces levels * Starting smoking, or smoking more * Stopping drinking Increases levels * Alcohol binges
94
Clozapine ECG arrhythmia
ST elevation due to myocarditis
95
Agranulocytosis mx
96
Poor compliance antipsychotic Mx
considered for once monthly IM antipsychotic depot injections
97
Neuroleptic malignant syndrome
Complication of taking antipsychotics
98
Neuroleptic malignant syndrome presentation (4)
* Hyperthermia * Altered mental status - agitation, cofnusion * Muscle rigidity * Urinary incontinence
99
NMS Ix
* **Creatine kinase** * Raised * Degree of muscle breakdown due excessive contractions * U&E * WCC * LFTs
100
NMS Mx
* Stop antipsychotic * Psych input if MH concern * Cooling blankets * For hyperthermia * Dantrolene * Rigidity * Also ± Bromocroptine * Benzodiazepines * Agitation * Fluids * If AKI
101
Potential ECG changes in clozapine/ antipsychotics
ST elevation due to cardiac failure secondary to myocarditis and cardiomyopathy
102
Personality disorder
Deeply ingrained and maladaptive pattern of behaviour persisting over many years. ## Footnote In mental health, the word ‘personality’ refers to traits that we developed as we grow up which make each of us an individual. These include the ways that we: think, feel and behave. Personality disorders manifest as experiencing significant difficulties in how you relate to yourself and others and having problems coping day to day stemming from your personality.
103
Categorisation of personality disorders - ICD-11 v cluster
ICD-11 1. Severity: Mild --\> Moderate --\> Severe 2. Trait domain Clusters * A- 'odd cluster' * B - 'dramatic cluster' * C - 'anxious cluser'
104
ICD-11 traits (5)
* Negative affectivity: tendency to experience broad range of negative emotions with a frequency and intensity out of proportion with the situation * Dissocial: disregard for others' rights and feelings - encompassing both self-centredness and lack of empathy * Disinhibition: tendency to act rashly based on immediate external or internal stimuli without consideration of potential negative consequences * Anankastic: narrow focus on one's rigid standard of perfection/right and wrong - controlling one's own and other's behaviours and situations to ensure conformity to these standards * Detachment: tendency to maintain interpersonal distance and emotional distance
105
Personality disorder clusters
A- 'odd cluster' * Paranoid * Schizoid * Schizotypal B - 'dramatic cluster' * EUPD * Histrionic * Antisocial C - 'anxious cluser' * Avoidant * Anankastic * Dependent
106
3 Ps of personality disorders
* Pervasive * Persistent * Pathological
107
Personality disorder Mx
Bio * SSRI * Antipsychotics Psycho * CBT * DBT * EUPD * MBT * Arts therapy Social * Therapeutic communities
108
Avoidant personality disorder
Often solitary existence due to feelings of inadequacy and fear of rejection and judgement from others.
109
Obsessive-compulsive personality disorder
* Occupied with details, rules, organization * Dedicated to work and efficiency to the elimination of spare time activities * Rigid about etiquettes of morality, ethics, or values * Unwilling to pass on tasks or work with others except if they surrender to exactly their way of doing things
110
Schizoid personality disorder presentation
* Disinterest in social relationships * Emotional coldness * Preference for solitary activities * Few interests * Indifference to praise/criticism
111
Schizotypal personality disorder
* Cognitive or perceptual distortions * Eccentricities of behaviours * Paranoia * Resulting in lack of relationships
112
Adjustment disorder
an emotional or behavioral reaction to a stressful event or change in a person's life
113
Charles-Bonnet syndrome
visual hallucinations associated with eye disease - most common hallucinations are faces, children and wild animals.
114
Delusional parasitosis
delusion that they are infested by 'bugs'
115
Depersonalisation-derealisation disorder
Depersonalisation: persistently or repeatedly have the feeling that you're observing yourself from outside your body Derealisation: you have a sense that things around you aren't real
116
Erotomania
* a.k.a De Clérambault's syndrome * Delusion that a famous person is in love with them, with the absence of other psychotic symptoms
117
Formication
Feeling of insects crawling under your skin
118
Illusion
sensory stimulus is present but incorrectly perceived and misinterpreted
119
Microspia
Things are perceived to be smaller than they are
120
Othello's syndrome
paranoid delusional jealousy, characterized by the false absolute certainty of the infidelity of a partner, leading to preoccupation with a partner's sexual unfaithfulness based on unfounded evidence
121
Signs of dependence
* Increased tolerance * Prioritising over other things * Continuing despite negative consequence
122
Going sober Mx
Bio *Acute* * Outpt or inpt reducing dose of Chlordiazepoxide (alcohol withdrawal syx mx) * Thiamine *Longer term* * Acamprosate * Reduces cravings Psycho * Motivational interviewing Social * Alcoholics anonymous * OT help * Work, finance, housing, etc ! To stop gradually
123
Alcohol withdrawal presentation
* anxiety after waking * sweating and tremors * nausea or retching in the morning * vomiting * hallucinations * seizures or fits
124
Alcohol withdrawal timeline
Symptoms: 6-12 hours Seizures: 36 hours Delirium tremens: 72 hours
125
Delirium tremens presentation
* agitation * confusion * autonomic dysfunction (e.g. high blood pressure, sweating and pyrexia, raised heart rate) * hallucinations * tremors
126
Wernicke's encephalopathy presentation
* Disorientated * Horizontal nystagmus * Difficulties in heel-toe walking
127
Korsakoff's syndrome
* Able to give consistent account of long term memory * Recent history inconsistent * Horizontal nystagmus
128
Alcohol withdrawal Mx
* Admit for medical observation * Descending regime of long-acting benzodiazepine, e.g., Chlordiazepoxide or Diazepam * +**Pabrinex** (Thiamine)
129
Drug (sub) used for opioid dependence
Methadone hydrochloride or buprenorphine
130
Benzodiazepines use
Acute bouts of anxiety * sedation * hypnotic * anxiolytic * anticonvulsant * muscle relaxant Use for 2-4 weeks only - development of psych and physical dependence
131
Benzodiazepines mechanism of action
enhance the effect of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) by increasing the frequency of chloride channel
132
Benzodiazepines examples
* Lorazepam * Diazepam * Temazepam
133
Benzodiazepines overdose presentation
Sedation
134
Which benzodiazepine causes the largest problem re withdrawal?
Lorazepam ## Footnote Shortest half-life -\> levels in body decrease rapidly
135
Benzodiazepines withdrawal presentation
* Confusion * Slurred speech * Unsteady gait
136
Benzodiazepine withdrawal Mx
IV Flumazenil
137
Stopping benzodiazepines
Reduce dose in steps of 1/8th of daily dose every fortnight
138
Benzodiazepine overdose
IV Flumenazil
139
Benzodiazepines and pregnancy
First trimester exposure associated with increased risk of cleft lip
140
Cocaine overdose presentation
* Central chest pain * Agitation * Hyperthermia * Hallucinations
141
Opioid/heroin withdrawal presentation
* Runny nose * Dilated pupils * Goodsebumps/piloerection * Sweating/fever
142
Types of opioids
* Morphine (Heroin is formulated from morphine) * Codeine * Fentanyl * Tramadol
143
Opioid overdose presentation
* Drowsiness/ coma, * Respiratory depression * Pinpoint pupils
144
Opioid overdose treatment
Naloxone
145
Paracetamol overdose
Urticarial rash/anaphylactoid reaction not uncommon to NAC stop and restart slow down infusion and observe for 1 hour whilst closely moniroring
146
Eating disorder Qs
147
ED Ix
Bedside * Full physical exam * 12 lead ECG * Body weight and height * SCOFF questionaire Bloods * FBC * may show anaemia from malnutrition or GI losses * U&Es * hypokalaemia is suggestive of vomiting or laxative abuse * LFT * may be slightly elevated from malnutrition
148
What are the question in the SCOFF questionaire?
* 'Do you ever make yourself sick because you feel uncomfortably full?' * 'Do you worry that you have lost control over how much you eat?' * 'Have you recently lost more than one stone in a 3-month period?' * 'Do you believe yourself to be fat when others say you are too thin?' * 'Would you say that food dominates your life?'
149
Anorexia nervosa criteria
1. Restriction of intake relative to requirements leading to a significantly low body weight 2. Intense fear of gaining weight or becoming fat 3. Disturbance in the way in which one's body weight or shape is experienced +Lanugo hair, reduced BMI, brady, hypten
150
AN Ix
* U&Es * Low K+ * High phosphate * **Low** FSH, LH, oestrogens and testosterone * **Raised** cortisol and GH * Impaired glucose tolerance * ECG * T wave inversion due to hypokalaemia
151
AN Mx
Refer to specialist ED clinic - combo of * Nutritional advice * Anorexia-focused family therapy * Individual CBT Use of MHA for admission if BMI dangerously low at \<13
152
AN Complx
* Hypothyroidism
153
! Refeeding syndrome
Metabolic abnormalities which occur on feeding a person following a period of starvation
154
Refeeding syndrome Ix
* U&Es! * **Low Ca** * Low K * Low Mg
155
What scoring system is used in Refeeding syndrome?
MUST score ## Footnote *High risk: little nutritional intake \>10 days, unintentional weight loss \>15% over 3-6months, BMI\<16*
156
Bulimia nervosa presentation
* Overeating/binging * Purging * Calluses on knuckles
157
BN Ix
* ECG * T wave inversion due to hypokalaemia
158
BN Mx
Refer to specialist ED clinic - combo of: * Nutritional advice * Anorexia-focused family therapy * Individual CBT
159
memory loss ddx
160
MMSE Qs (name 3) and scoring
Scoring: 24-30 No cognitive impairment 18 - 23 Mild cognitive impairment 0-17 severe cognitive impairment
161
AMTS Qs (10)
162
Memory loss Ix
Bedside * MMSE * or AMTS * Urinalysis Bloods * FBC * U&E * B12/folate * TFTs * CRP Scan * CT/MRI head
163
Alzheimers v depression
Alzheimers has longer period of onset - often others notice syx as opposed to patient themselves Depression has biological syx e.g. weight loss, sleep disturb
164
Memory loss specific Qs
How are they when left alone? Doing anything unsafe? Self-neglect? Aggression?
165
Alzheimer's presentation
* Usually older person * Gradually worsening memory * Pays less attention * Problems w spatial orientation (getting loss in familiar places) * Behaviour changes as Alzheimer's progresses but not prominent at start
166
What increases risk of developing Alzheimer's?
Down's syndrome
167
Lewy Body dementia presentation
* Progressive memory loss (fluctuating) * Parkinsonism * Visual hallucinations
168
What type of hallucinations would you get with Lewy Body dementia?
* Small animals and people * Things are going slower
169
What drugs should be avoided in Lewy Body Dementia pts?
First generation/typical antipsychotics ## Footnote *(cause severe confusion, severe Parkinsonism, sedation and sometimes even death)*
170
Vascular dementia presentation
* Hx CVD * Cerebrovascular disease hx
171
Vascular dementia vascular RF Mx
Aspirin
172
Frontotemporal lobar degeneration
3rd most common type of dementia after alz and lew body's
173
Frontal temporal lobar degeneration presentation
Personality change and impaired social conduct
174
What MMSE score would fall under mild cognitive impairment?
20-25
175
What MMSE score would fall under moderate cognitive impairment?
15-19
176
What MMSE score would fall under severe cognitive impairment?
9-14
177
MRI findings 1) Alzheimer's dementia 2) Frontotemporal dementia
1) Hippocampal atrophy - part of temporal lobe (early feature) 2) Frontotemporal atrophy
178
Alzheimers mx
Bio * ACH-esterase inhibitor * e.g., donepezil, rivastigmine, galantamine * 2nd line: Memantine Psycho * Refer to memory clinic - old age psychiatrist (1) * Group cognitive simulation therapy Social * Occupational therapy assessment * Home safety, transport, care needs
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ECT SEs
Short term * Cardiac arrhythmias Long term * Memory impairment - retrograde amnesia
180
Relative CIs for ECT
* raised intracranial pressure * recent cerebrovascular accident * untreated cerebral aneurysm * myocardial ischaemia or uncontrolled cardiac failure * unstable major fracture * severe osteoporosis
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Circumstantiality
Circuitous and non-direct thinking or speech that digresses from the main point of a conversation, however the final goal of the conversation will be reached. Common in anxiety disorders and hypomania.
182
Clang associations
when someone uses words that rhyme with each other or sound similar
183
Delusion of passitivity/ passitivity phenomena/ delusion of control
Delusion that their actions are being controlled
184
Echolalia
repetition of someone’s speech
185
Flight of ideas
patient speaks very quickly and rapidly jumps between different topics ## Footnote *Common in mania*
186
Knight's move thinking/Loosening of association
No clear links between successive thoughts Common in psychosis
187
Neologism
formation of new words
188
Perseveration
ideas or words are repeated several times
189
Tangentiality
Wandering from topic without returning to it
190
Thought withdrawal
Belief of having the removal of a thought by an external force ## Footnote *Common in Schizophrenia*
191
Conversion disorder
loss of motor or sensory function. May be caused by stress
192
Factitious disorder
a person, without a malingering motive, acts as if they have an illness by deliberately producing, feigning, or exaggerating symptoms, purely to attain (for themselves or for another) a patient's role.
193
Hypochondira/Illness anxiety disorder
persistent belief in the presence of an underlying serious disease, e.g. cancer
194
Malingering
fraudulent simulation or exaggeration of symptoms with the intention of financial or other gain
195
Sleep paralysis
transient paralysis of skeletal muscles which occurs when awakening from sleep or less often while falling asleep ±hallucinations during the paralysis *\***Clonazepam may be considered*
196
Somatisation disorder
multiple physical SYMPTOMS present for at least 2 years with no organic cause found
197
Suicide hx
198
Suicide risk assessment
199
Counseling - explanation
200
COmmon drug explanation
201
IQ - Extremely low/ learning disability
Under 70
202
ADHD Mx
Bio * Methylphenidate * 5 and above ​Psycho​ * Family therapy \<1st line\> Social * Parental training
203
Conduct disorder presentation
* Violence * Enjoy causing harm, lying * Ignoring rights/feelings of others
204
Conduct disorder Mx
Multisystemic (family) therapy
205
Steps for de-escalating situation
1. Verbal de-escalation 2. IM Lorazepam
206
Psych PACES gen tips
+ICE
207
Who is able to section under the MHA?
Requires two doctors and an Approved Mental Health Professional. At least one doctor must be “approved” under s12 MHA, and ideally the other doctor would know the patient (usually a GP). The AMHP is often a social worker.
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Section 2
Assessment - 28 days
209
Section 3
Assessment and treatment - 6 months
210
Section 5(2)
Dr's holding power - 72hours
211
Section 5(4)
Nurse's holding power- 6 hours
212
Section 135
Police can enter your property
213
Section 136
Police can bring someone from public place to a safe space
214
What pathophysiology would you expect for 1) Alzheimer's 2) Lewy body dementia 3) Vascular dementia
1) Amyloid plaques and neurofibrillary tangles (tau protein) 2) Lewy bodies (eosinophilic) deposits 3) Thromboembolic or hypertensive infarction
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Schizoaffective disorder
Symptoms of schizophrenia and mood disorder are equally prominent
216
Persistent delusional disorder
Most pervasive symptom is delusion
217
Schizophrenia dx criteria
Over period of one month patient must have 1 first rank syx or at least 2 other syx
218
Delirium mx
* Re-orientate (glasses/hearing aids, clock/orientation reminders/familiar objects/adequate lighting) * Identify and treat underlying causes (infection/pain/constipation…) * Medication – halorperidol, benzodiaepines
219
Onset of Alzheimers
Gradual, progressive
220
Onset of Lewy body dementia
Insidious onset, progressive with fluctuations
221
Onset of vascular dementia
Abrupt or stepwise
222
Onset of frontotemporal dementia
Insidious onset, rapid progression
223
Puerperal psychosis RFs
* Previous episodes of psychosis * History of bipolar disorder * First time mothers * After instrumental delivery * FH of affective disorder
224
Puerperal psychosis mx
Admit to mother and baby unit ±antipsychotics ± ECT
225
Extracampine hallucination
Perceived hallucination is beyond limits of normal sensory perception, e.g., hearing an alien speaking from Mars
226
Pareidolic illusion
Seeing things, .e.g, faces and animals, in things
227
Elemental hallucination
Flashes of lights/sound etc
228
Drugs which can cause psychosis
* Cannabis * Steroids * Cocaine
229
How long does it take to recover from puerperal psychosis?
6-12 weeks
230
Puerperal psychosis RFs
* Previous puerperal psychosis * FHx PP * Underlying MH dx esp BPAD * Obstetric complx
231
What is DBT/how does it work?
Focuses on factors contributing to emotional instability which lead to a vicious cycle where you experience intense and upsetting emotions, which make you feel guilty and worthless and leads to actions that can make you feel upset again * DBT aims to introduce two important concepts: * **Validation**: accepting that your emotions are acceptable * **Dialectics**: showing you that things in life are rarely black or white, and helping you be open to ideas and opinions that contradict your own