Psych Flashcards

(42 cards)

1
Q

small molecule transmitters

A

amino acids (NT)
monoamines (NM)
acetylcholine (NM)
NO

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2
Q

amino acid neurotransmitters

A

glutamate: excitatory
GABA: inhibitory

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3
Q

monoamines neuromodulators

A

catecholamines (NE/epi/dopamine)
serotonin
histamine

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4
Q

function of NE/epi

A

sympathetic, wakefullness, arousal, attention, memory

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5
Q

function of dopamine

A

reward/motivation and executive function/motor control

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6
Q

function of serotonin

A

wakefullness, cognition, mood, appetite

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7
Q

function of acetylcholine

A

acts on nicotinic and muscarinic receptors at neuromuscular junction to activate parasympathetic system

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8
Q

large molecule transmitters

A

neuropeptides

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9
Q

neuropeptides

A

substance P/tachykinins: pain perception
kisspeptin/tachykinins: reproductive function
orexin: wakefullness
proopiomelanocortin: feeding and metabolism
endogenous opioids
cannabinoids

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10
Q

GABA synthesis

A

from gultamate, using vitamin B6

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11
Q

function of glutamate

A

predominant excitatory NT of brain, expressed everywhere

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12
Q

receptor of glutamate

A

ionotropic (fast/excitatory)

GPCR (slow/inhibitory and excitatory)

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13
Q

clearance of glutamate

A

pre/post/glial cell uptake receptors

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14
Q

function of GABA

A

predominant inhibitory NT of brain, expressed everywhere

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15
Q

receptor of GABA

A

ionotropic and metabotropic

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16
Q

clearance of GABA

A

pre/glial cell uptake receptors

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17
Q

receptor for acetylcholine

A

ionotropic (nicotinic)

metabotropic (muscarinic)

18
Q

synthesis of acetylcholine

A

from acetyl CoA and choline

19
Q

location of acetylcholine expression

A

basal forebrain and brainstem

20
Q

clearance of acetylcholine

A

acetylcholine esterase

21
Q

location of NE expression

A

pons, brainstem

22
Q

location of epi expression

23
Q

receptors for NE/epi

A

alpha1, alpha2, beta2 (heart)

24
Q

clearance of NE/epi

A

pre-synaptic autoreceptors

25
formation of NE/epi
from tyrosine
26
synthesis of dopamine
from tyrosine
27
receptor for dopamine
GPCRs G1=stimulation, G2=inhibition
28
clearance of dopamine
DAT
29
synthesis of seratonin
tryptophan
30
receptors for seratonin
many! both ionotropic and metabotropic
31
nucleii locations of seratonin
brain and gut
32
clearance of seratonin
SERT (pre-synaptic)
33
receptor for endophins
mu
34
receptors for enkephalins
delta
35
receptors for dyrnophins
kappa
36
receptor for endomorphins
mu
37
sensory aphasia (Wernicke)
inability to comprehend written or spoken words, some difficulty speaking
38
motor aphasia (Broca)
non-fluent speech
39
global aphasia
both Broca and Wernicke
40
depersonalization
disorder of perception, feel dissociated from sensations
41
psychoanalysis
promotes awareness of unconscious, maladaptive and habitually recurrent patterns of emotion and behavior
42
supportive psychotherapy
reinforcement of patent's healthy and adaptive patterns of thought. unlike psychoanalysis because the therapist is an encouraging, supportive team member.