Psych

Question 1

What drugs cause weight gain?

Answer 1

Mirtazapine, Olanzapine, Clozapine

Question 2

What drug for depression in pregnancy?

Answer 2

Sertraline

Question 3

What mood stabiliser in breast feeding?

Answer 3

Lamotrigine

Question 4

Old lady who has insomnia?

Answer 4

Give her mirtazapine

Question 5

What is the least sedating antipsychotic?

Answer 5

Aripirazole (atypical)

Question 6

What antidepressants are not sedating?

Answer 6

Most SSRIs are not sedating and duloxetine is not sedating.

Question 7

What antidepressant in children

Answer 7

Fluoxetine

Question 8

What is the only antipsychotic that does not cause weight gain?

Answer 8

aripiprazole

Question 9

What antidepressants do not cause you to gain weight?

Answer 9

Fluoxetine and duloxetine.

Question 10

What class of antidepressants should you avoid in the elderly?

Answer 10

SSRIs

Question 11

MAOI + SSRI can cause what

Answer 11

Serotonin Syndrome

Question 12

What treatment for delirium? What if they have Parkinson’s /Lewy body dementia?

Answer 12

haloperidol, quetiapine

Question 13

3 side effects of SNRIs?

Answer 13

venlafaxine and duloxetine,

hypertension
insomnia
cardiac arrhythmias.

Question 14

TCAs

Answer 14

Amitriptyline, imipramine, dosulepin, clomipramine, nortriptyline, trazodone

contraindicated in post MI patients

Anti cholinergic side effects.

Question 15

HPT axis in depression

Answer 15

TSH to TRH response blunted in 20 - 25% despite normal TSH, T3 and T4

Question 16

HPA axis in major depression

Answer 16

50-70% fail to suppress cortisol production following administration of dexamethasone.

Question 17

Brain imaging in OCD?

Answer 17

Increased metabolism and blood flow in orbitofrontal cortex, caudate nucleus and cingulate cortex.

Question 18

Memory encoding location?

Answer 18

Ventrolateral pre frontal cortex and medial temporal cortex.

Question 19

How do we measure white matter tracks in schizophrenia?

Answer 19

Diffusion tension imagine (DTI)

Question 20

Mesolimbic / cortical pathway

Answer 20

Motivation and reward.

Question 21

D1 and D5

Answer 21

Stimulate cAMP

Question 22

D2, D3, D4

Answer 22

inhibit Ca2+, open K+ channels

Question 23

Borderline learning difficulty

Answer 23

70-80

Question 24

Mild LD

Answer 24

50-69

Question 25

Moderate LD

Answer 25

35-49

Question 26

Severe LD

Question 27

Profound

Question 28

How do we calculate IQ?

Answer 28

mental age/chronological age x 100

Question 29

Schizophrenia is 3x more common in people who have learning difficulties

Answer 29

Depression is 3x more common in people who have learning difficulties.

Question 30

Functional hemiparesis brain imaging

Answer 30

Increased rCBF bilaterally in frontal and parietal cortex in resting states.

Question 31

First rank symptoms

Answer 31

Delusional perception Passivity (Delusions of control) Auditory Hallucination Delusions of though interference

Question 32

Social anxiety treatment

Answer 32

Moclobemide

Question 33

Social phobia imaging

Answer 33

increased bilateral activation of amygdala that normalises after treatment

Question 34

Treatment of neuroleptic malignant syndrome?

Answer 34

Dantrolene and bromocriptine (dopamine agonist)

Question 35

Selective abstraction

Answer 35

Focus on one -ve detail, colours entire experience.

Question 36

Schizophrenia Dx?

Answer 36

Diagnosed after 6 months of symptoms: 1 first rank OR 2 negative symptoms

Question 37

CAGE

Answer 37

C ut down A angry when people talk about your drinking G uilty E ye opener, drink in morning

Question 38

Orbitofrontal cortex

Answer 38

Key creator of motivation to act Addicts show increased activation of OFC when presented with drug cues. The changes persist into abstinence.

Question 39

End of life medication

Answer 39

Resp secretions = buscopan Nausea = Levopromazine Distress = midazolam Pain / SOB = Morphine

Question 40

Increase of what in alcohol dependence?

Answer 40

Increased levels of GABA.

Question 41

Withdrawal alcohol seizures?

Answer 41

0 - 48 hours

Question 42

Delirium Tremens

Answer 42

48 - 72 hours.

Question 43

What is the only atypical antipsychotic not to cause EPSE?

Answer 43

Clozapine (only antipsychotic to act on D4)

Question 44

What atypical is more likely to cause hyperprolactinaemia?

Answer 44

Risperidone

Question 45

Treatment of Borderline PD

Answer 45

DBT

Question 46

Treatment of Avoidant PD

Answer 46

Social Skills training

Question 47

Cluster A personality Disorder

Answer 47

Schizoid Paranoid Schizotypal

Question 48

Cluster B Personality Disorder

Answer 48

Borderline Histrionic Antisocial

Question 49

Cluster C

Answer 49

Obsessive compulsive Avoidant Dependent

Question 50

Carbamazepine side effects?

Answer 50

``` Dizzy and drowsy N & V Dry mouth and swollen tongue Hypothyroid Aplastic anaemia ```

Question 51

Lamotrigdine side effects

Answer 51

SJS Sedation Ataxia Insomnia

Question 52

B Blockers side effects

Answer 52

Fatigue, cold peripheries, erectile dysfunction

Question 53

Statins side effects

Answer 53

Myalgia

Question 54

Autism Treatment

Answer 54

Risperidone for short term aggression Ritalin for ADHD symptoms Melatonin = difficulty sleeping.