Psych Flashcards

(137 cards)

1
Q

Antidepressant used after MI/ Coronoary heart disease

A

Sertraline

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2
Q

Antidepressant causing Long QT

A

Citalopram

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3
Q

Antidepressant with long half life (so no withdrawal)

A

Fluxoetiene

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4
Q

Rapid tranquillisation drugs

A

IM Lorazepam, Haloperidol

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5
Q

Clozapine Use

A

Treatment resistant Schizophrenia

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6
Q

Definition of Treatment resistant depression

A

failure to respond to 2 or more antipsychotics (1 of which is atypical) @theraputic dose for more than 6 weeks

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7
Q

Emergency side effect with Clozapine and how to prevent

A

Angranulocytosis - occurs in 0.7%

Weekly blood test to look for neutropenia

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8
Q

What is dystonia? What causes it

A

Involuntary, painful, sustained muscle spasms
onset within hours
Neck twist - torticollis
eyes twist up and can’t look down - oculogyric crisis

Extra-pyrimidal side effects (EPSE)
with typical antipsychotics

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9
Q

How do you treat dystonia

A

IM Procylidine/Benztropine (Anti-CHolinergic

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10
Q

What is Akathsia

A

Unpleasant subjective restlessness e/g leg jiggling

EPSE

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11
Q

How do you treat akathisia

A

Propanolol

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12
Q

What is Tardive Dyskinesia

A

Rhythmic involuntary movements e.g grimacing –> often irreversible

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13
Q

How do you treat Tardive Dyskinesia

A

Stop antipsychotics or change to atypical
Tetrabenazine
DON”T USE ANTICHOLINERGICS

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14
Q

What drugs cause Hyperprolactianemia and what does that cause

A

Typical antipsychotics

Amenorrhoea, gynaecomastia, hypogonadism, sexual dysfunction, osteoporosis risk

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15
Q

Schizophrenia first rank symptoms

A

Delusional perceptions
Passivitiy –> believing that things are being controlled e/g movements
Thought interference - Withdrawal, insertion, broadcast
Auditory Hallucinations –> thought echo or 3rd person

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16
Q

What is Hebephrenic Schizophrenia

A

Disorganised and chaotic mood/behaviour/speech
Often Childish
Less delusions and hallucinations

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17
Q

What is posturing and what do you get it with

A

Maintain bizzarre positions

Catatonic schizo

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18
Q

What is waxy flexibility

A

Can put them in weird positions and they’ll hold

Catatonic schizo

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19
Q

What is perserveration

A

Inappropriate repetition of words/actions

Catatonic scizo

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20
Q

What is rigidity

A

They won’t move when you try to move them

Catatonic schizo

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21
Q

4 key features of PTSD

A

Intrusive symptoms/re-experiencing
Avoidance
Hyperarousal
Emotional deficits e.g detachment

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22
Q

4 treatments of PTSD

A

CBT
Eye movement desensitisation and reprocessing
SSRI/SNRI
Support groups

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23
Q

Adjustment disorder trigger and length

A

Prolonged severe abnormal response to a stressful life event (e.g divorce) beginning within. 1 month and lasting no more than 6m
Symptoms of anxiety

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24
Q

How long should a manic episode last

A

1 week

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25
A patient is hyperaroused but is able to go to work - is this mania or hypomania
Hypomania --> mania requires disruption to day to day life
26
MZ% of depression
44%
27
DZ% of depression
20%
28
Lifetime risk of schizo
1%
29
How long does it take SSRIs to work
4-6w
30
Which class of antidepressants are cardiotoxic in overdose
TCAs
31
Name some side effects of SSRIs
``` Initial suicidal ideation Sexual dysfunction Drowsiness (esp with ETOH) Decreased seizure threshold Hyponatraemia N&V Blurred vision Anxiety Sweating tremor Persistent pulmonary hypertension in the newborn ```
32
Which drugs are most often implicated in serotonin syndrome
MAO-I
33
Which drugs cause the cheese reaction with tyramine rich foods
MAOI- cheese reaction
34
When would you use ECT in depression
Psychotic or v severe irretractible depression (affecting things like eating and drinking
35
How long should depressive symptoms last
2w
36
3 key depressive symptoms
Anergia Anhendonia Low mood
37
MZ risk of BPAD
80%
38
DZ risk of BPAD
20%
39
Risk with first degree relative
8%
40
Type 2 BPAD
Mainly depression w/ hypomania
41
Type 1 BPAD
Mania w/ depression
42
Rapid cyclic BPAD
4 or more episodes a year
43
Treatment for Rapid Cyclic BPAD
Sodium Valproate
44
Lithium Overdose
GI disturbances, ataxia, tremor, fit, renal failure, slurred speech, arythmia
45
Can you use Sodium Valproate in pregnancy
NO - give folate and contraception advice
46
What anomaly does Lithium cause in pregnancy
Ebstein's anomaly - Atrialisaiton of the right heart, tricuspid valve moves down, right to left shunt thru ASD/PFO
47
Should you give antidepressants in BPAD
Only with a mood stabiliser as can trigger mania
48
MZ for schizo
Around 50%
49
DZ for schizo
4%
50
1º relative for schizo risk
10%
51
How long should anxiety symptoms last for diagnosis
6m
52
What is Wernicke's encephalopathy + Cause
Thiamine deficiency | Causes Ataxia, confusion and eye problems (ophthalmoplegia & nystagmus)
53
What is Korsakoff's syndrome
Irreversible anterograde amnesia - can't remember new events | Will confabulate to fill in the gaps
54
Questionaire for alcohol
CAGE - Have you ever felt you needed to Cut down on your drinking? Have people Annoyed you by criticizing your drinking? Have you ever felt Guilty about drinking? Have you ever felt you needed a drink first thing in the morning (Eye-opener) to steady your nerves or to get rid of a hangover?
55
Delerium trememns onset and symptoms and treatment
``` ~48 hours into abstinence Confusion Hallucinations esp visual Gross tremor Autonomic disturbance Affective changes - fear, hilarity Delusions ``` Treat with reducing chlordiazepoxide regimene + thiamine (pabrinex)
56
Dependcey features ``` Take Care With Problematic Substances, Really Can Need ```
``` Tolerance Compulsion Withdrawal problems controlling use Salience - become so imptortant to use other needs are neglected Reinstatement after absitnance Continued use despite harm Narrowing of repitoire ```
57
What do you have to do in every fucking PACEs station
Risk assess - risk to self, to others, vulnerability, suicide etc
58
Delirium Causes
``` Trauma Hypoxia Infectioon Metabolic - liver/renal failure, electrolyte imbalance Endocrine - hypoglycaemia CNS pathology Drug withdrawal ```
59
Delirium features
``` Sudden onset (days-weeks) Fluctuating consciousness Short duration <6m Impaired consiousness Poor atention Disorganised thinking Delusions - transient, muddled Hallucinations - visual Treat underlying cause ``` LOOK OUT FOR HYPOACTIVE DELIRIUM - stupour, drowsiness, withdrawal
60
Agorpaphobia Definitions
Fear of being unable to escape to safe place
61
Key features of OCD
Obsessions - recurrent intrusive thoughts --> recognised as unpleasant, irrational, and the patients own Compulsions - to try and reduce the anxiety
62
What is an acute stress reaction
``` Occurs after a traumatic event Happens within minutes and should resolve within hours Depresonalisation and derislisartion Disorientation Agitated, panicky ```
63
Somatisitation
``` Rare, disabling, chronic Multiple medically unexplained symptoms Frequently changing symptoms Symptoms persist for more than 2y Multiple investiagations Refusal to accept advice ``` Rx - don't conduct further investagations, involve family, try to give them copping strategies
64
Schzioaffective disorder
Both mood disorder (usually BPAD-like) and schizophrenia in the same episode
65
Bulimia key features and Rx
Preoccupation with eating and body weight Binginging food Then purging - laxative, vomiting Signs of vomiting - parotid swelling, dental erosion, Russell's sign (calluses on dorsal of hand) & calluses on finger Weight often normal Have insight - often want help can cause cardiac arrhythmia and renal failure Rx - CBT, interpersonal psychotherapy, SSRIs e.g fluoxetine (help impulse control as well as depression)
66
Examples of dissociative disorders
Dissociative Amneisa Dissociative fugue - purposeful trip away from home, new identity Dissociative stupor - motionless and mute but aware of surroundings Rx - usually spontaneously resolves, can give supportive therapy to increase insight and help with stress management
67
Anorexia Key symptoms
Weight loss by diet restriction and one of: 1) self induced vomiting 2) excessive exercise 3) appetite suppressants or diuretics 4) laxatives ``` BMI <17.5 Morbid fear of fatness Body image distortion Loss of libido Fatigue Amenorrhoea ```
68
Anorexia signs
``` Guant Dehydrated Proximal myopathy cold extremities bradycardia and hypotenison Exhibit peripheral oedema Parotid gland enlaegmenet and erosion of tooth enamel if vomting ``` ``` Can cause - osteoporosis, cardiac arrhythmia (2º to hypokalaemia), pancreatitis, hepatitis (nuturiton - low serum protein, raised bilirubin, LDH, ALP) seizures, peripheral neuropathy, pancytopenia, suicide ```
69
Anorexia Blood tests
``` Low: Hb U+E Phsophate Glucose T3 FH/LH/E2 Ca Mg Cl ``` ``` Raised: ALp Bilirubin CK Amylase Cortisol Growth Hormone Cholesterol ```
70
Rx for anorexia
Psycho-deucation Treat comorbid psych issues Nutritional management and weight restoration Motivation interviewing - try to engage ambivalent patients Family therapy Interpersonal therapt CBT Medical treatment - esp if physical complications, rapid weight loss of BMI<13.5 Inpatient - BMI <13, extreme rapid wt loss, serious physical complications high suicide risk
71
When to admit anorexia patients --> high risk
BMI <13 Weight loss >1kg a week purpuric rash cold peripheries Core body temp less than 34.5 hypotensions (Systolic <80, diastolic <50) bradycardia <40 Prolonged QT Inability to stand from squatting wo/ using arms (squat test) Electrolyte imbalance (K<2.5, Na <130, PO4 <0.5)
72
what blood tests should be checked on lithium
U+E TFTs Lithium levels
73
Criterial for learning disability
IQ <70 Mild - 50-69 Moderate - 35-49 Severe - 20-34 Profound <20
74
Postnatal depression % and signs
10% of mothers Insidious onset over weeks, ~3m (or progress from baby blues) Obsessive recurrent intrusive thoughts about harming baby Depressive cognitions --> guilty, failure of a mother Rx - support, admission to mother and baby unit, consider antidepressants 90% respond to treatment within 1m
75
baby blues
Begin within 10d Tearful, weepy, muddled, liability of mood NORMAL - occurs in up to 3/4 Reassure, family support, antenatal education
76
Puerperal pscyhosis signs
``` 1 in 500-1000 ~2w after birth Marked restlessness and fear perplexity - can't deal with it Then psychotic symptoms: affective disorder, delusions e.g baby is possed/evil Command hallucination to hurt baby ``` Symptoms can fluctuate quickly Antipsychotics, mood stabilisers, antidepressants (Avoid lithium if breast feeding if possible) most settle in 6w and fully recovered by 6m
77
What condition is linked with OCD
Tourrettes
78
Signs of foetal alcohol syndrome
A smooth philtrum: The divot or groove between the nose and upper lip flattens Thin vermilion: The upper lip thins Small palpebral fissures (opening of eyelid): Eye width decreases Skin folds at corner of eye short nose small head Foetal growth retardation/short stature Behaviuoural difficulties learning disabilities neurological problems - epilepsy, hearing loss
79
3 key features of ASD
1. Lack of reciprocal social interaction --> not interested in people, poor attachment, weird eye contact, can't read emotions 2. Restricted behaviours and routine - repetitive, stereotype behaviour 3. Communication abnormalities - concrete thinking, absent gestures, absent expressive speech, delayed comprehension, speech disorders (monologues, formal pedantic language, pronoun reversal) hypo or hyperactivity to sensory input ¡present in early childhood! Impair everyday functioning
80
Enuresis 1º and 2º - causes and management
1º - toilet training never mastered - usually delayed bladder innervation or developmental delay (but stress and relaxed or strict toilet training can cause) 2º - dry for a year but lost --> usually stress related Rx - refer to paediatrics, reassure child and family, restrict fluids, start charts, Bell and Pad (underpants alarm), TCA or desmopressin
81
Encopresis - causes and management
Inappropriate defecation after age 4 Boys more commonly affected Mostly relate to constipation - due to dehydration, painful defecation (e.g fissure), fear of punishment, toilet fears, Hirschsprung disease Also due to diarrhoea, learning difficulties , occasionally hostile, stress Rx - Laxitives for constipation, reassure, review toilet training, star charts
82
What test does every child with suspected ASD need
HEARING TEST
83
Asperger's syndrome
Poor social skills and restricted interest w/ normal language and IQ
84
Rx for ASD What other conditions are associated w/ ASD
Support, behaviour therapy, speech and language therapy, special education 75% have learning disabilites 25% have epilepsy
85
Ertonomania
delusion that the individual is loved by someone famous
86
Knight's move
Odd tangential association between ideas lead to disruption of speech Can't follow connection between topics unlike flight of ideas
87
Flight of ideas
Stream of accelerated thought with abrupt changes, but can usually follow associations (e.g alliteration, homonoyms) is a form of pressure of speech
88
Neologism
Invent a new word
89
Loosening of assocations
Connections between patients thoughts are difficult to follow
90
Dysthymia
Chronic low mood not meeting depression standards
91
Hypochondirasis
Fear of having a specific severe illness, in the absence of real organic pathology
92
Formication
Feel insects under skin
93
word salad
Inchoherent mess of words and phrases
94
Section 2
Lasts 28 days For assessment Needs AMHP, and 2 doctors (1 S12)
95
Section3.
Lasts. 6 m for treatment Need 2 doctor (1 s12) and AMHP
96
Section 5(2)
Holding power for patient on ward Need 1 docto Last 72 hours
97
Section 136 -
Police remove from public to safe place | Last 72 hours
98
Section 135
Police remove from house to save place
99
Section 5(4)
Nurses holding power for someone on ward | last 6 hours
100
CTO
Have to take treatment while living in community, and can be recalled to hospital for someone who was under a section 3
101
Section 4
Emergency section for 72 hours, require one doctor and AMHP
102
Abnormal grief reaction time scale
Lasts more than 2 years or delayed onset | self neglect
103
Indicators of serious self harm attempt
Planned and premeditated Final acts in anticipation - closing accounts, writing notes Violent/dangerous methods Trying not to be found People who think the act would be irreversible Didn't seek help/angry someone helped them Regrets surviving Numerous previous attempts Still hopeless for future
104
Anti-ETOH drugs
Acamprostate - anti-craving drugs Disulfram - causes build up of acetaldhyde, which is unpleasant Naltrexone - opioid antagonist, reduces pleasure of alcohol
105
Buprenorphine
Partial agonist of µopioid receptor Blocks euphoric effects wo/ withdrawal Sublingal tablet
106
Methadone
Liquid Long half life Full agonist at opiate receptors
107
Neonatal abstinence syndrome
``` Babies born to heroin addicted mothers Suffer with withdrawal symptoms --< start within hours, can last weeks High pitched cry restlessness tremor hypertonia convulsions diarrhoea vomiting sweats fever tachypnoea ``` Rx - neonatal opiate preparations, anti-convulsants, supportive measures (opiates can also cause IUGR, low birth wt, prematurity, and risk of SIDS increased)
108
Conduct disorder
10% of 10 year olds 4x more common in boys RF - urban, parental criminality, harsh/inconsistent parenting, maternal depression, deprivation Persistantly bullying, sterling, fighting Socialised - have friends who they are antisocial with Unsocilaised - rejected by other children
109
Oppositional defiant disorder
Milder form of CD In children under 10 provocative, disobidient behaviour towards adult No extreme antisocial behaviour
110
what age does ADHD present
~6
111
What are the main features of ADHD
Inattention - chaotically flit between tasks, distractible Hyperactive - excess energy, loud Impulsivity and disinhibition - can't share, social disinhibited (butt in) disorganised ``` These are worse in unfamiliar envorinments Short tempered Poor social relationships Do poorly at school Low self esteem ```
112
Rating scale for ADHD
Conners rating scale
113
Ix for ADHD
Questionaires, Classroom observation Child psych + paeds assessment Educations psychologist assessment
114
Rx for ADHD
Educate parents and teachers Active promotion of behaviour and education process with kid - advice on behaviour modification, building concentration, self esteem Behaviour intervention - clear rules and expectations, clear rewards and consequences Advice that dietary restriction doesn't help Try behaviour and education therapy first + family therapy, before giving drugs But if really severe can give at same time Methylphenidate or dexamphetamine reduce motor activity (can cause growth retardation so drug holidays) Non-stimulant - atomoxetine (increase attention and decreases unwanted motor activity)
115
What other conditions are associated w/ ASD
up to 75% have learning difficulties | 25% have seizures/epilepsy
116
Paranoid personality disorder
``` Group A - paranoid bois SUSPECT Sensitive Unforgiving --> grudges Suspicious Possessive and jealous Excessive self-importance Conspiracy theories Tenacious sense of rights ```
117
Schizoid Personality disorder
``` Group A - socially withdrawn and flat ALL ALONE Anhedonic Limited emotional range Little sexual interest ``` ``` Apparent indifference to praised/citicism Lacks close relationships One player activity Normal social convention ignored Excerssive fantasy world ```
118
Histironinc Personality disorder
Group B ACTORS ``` Attention seeking Concerned with own appearance Theatrical Open to suggestion Racy and seductive Shallow affect ```
119
Emotional Unstable PD - general
``` Group B AEIOU Affective Instability Explosive Behaviour Impulsive Outbursts of anger Unable to plan or consider consequences ```
120
EUPD - Borderline
``` Group B SCARS Self image unclear Chronic empty feelings Abandoment fears Relationships are intense and unstable Suicide attempts and self harm ```
121
EUPD - impulsive
``` Group B LOSE IT Lacks impulse control Outbursts or threats of violent Sesntivity to being thwarted or criticised Emotional instability Inability to plan ahead Thoughtless of consequences ```
122
Dissocial PD
``` Type B - angry bois FIGHTS Forms but can't maintain relationship Irresponsive Guiltless Heartless Temper easily lost Someone else thought ```
123
Anakastic PD
Type C - perfectionists DEFLATED ``` Doubtful Excessive detail Tasks not completed Adheres to rules Inflexible Likes own way Excludes pleasure and relationships Dominated by intrusive thoughts ```
124
Anxious/Avoidant personality disorder
Group C - anxious bois AFRAID ``` Avoids social contact Fears rejection/criticism Restricted lifestyle Apprehensive Inferiority Doesn't get involved unless sure of acceptance ```
125
Dependent personality disorder
Type C SUFFERS ``` Subordinate Undemanding Feels helpless when alone Fears abandomnet Encourages others to make decisions Reassurance needed ```
126
Personality disorder defintion
3Ps Pervasive - occurs in all/most areas of life Persistent - evident in adolescence and continues throughout adulthood Pathological - causes distress to self and others and impairs function ``` ICD 10 require following (REPORTD): Relationship affected Enduring Pervasive Onset in childhood adolescence Results in distress Trouble in occupational/social performance Don't have brain damage or another psych disorder ```
127
What is Derailment
Derailment is a type of formal thought disorder in which there are disjointed thoughts with no meaningful connections. It is commonly seen in schizophrenia, but also presents sometimes in other disorders.
128
What is Circumstantial thinking
Circumstantial thinking is somewhat difficult to describe but occurs when the person talks around a subject exhaustively with only loosely relevant associations. They will usually return to the point but only after many detours of almost irrelevant (or certainly over-inclusive) information
129
what is Cyclothymia
Cyclothymia | is diagnosed where there is persistent instability of mood with a cycle of low grade elevated and depressed mood
130
What is Logoclonia
Logoclonia describes the symptom of repeating the last syllable of a word repeatedly and is often seen in Parkinson’s disease
131
What is Echolalia
Echolalia is the phenomenon whereby words or sentences that the patient hears are repeated back, sometimes continuously and incessantly. It often has an organic cause such as dementia or brain injury but may also be seen in functional disorders such as schizophrenia
132
What is alogia
Alogia is the phenomenon of ‘not having any words’ and refers to extreme poverty of speech. It is commonly seen in severe negative schizophrenia or dementia
133
What is negativisim
Negativism is the symptom whereby catatonic patients will appear to automatically do the opposite of what they are asked to do. This is not just resisting instructions or movement but actually attempting to perform the opposite instruction or movement.
134
What is clanging
Clanging is a form of thought disorder whereby words are used based on their similar sounds or rhyming and the meaning becomes unimportant. For example, ‘A cat pat on my hat sack, ate the bait and skated’. It is seen in schizophrenia
135
Anorexia hormonal abnormalities
``` hypokalaemia low FSH, LH, oestrogens and testosterone raised cortisol and growth hormone impaired glucose tolerance hypercholesterolaemia hypercarotinaemia low T3 ```
136
electroylte abnormalities in refeeding sydrome and what causes it
low phosphate Low K Low magnesium Swtich from fat to carb metabolism causes increased secretion of insulin, moving these electrolytes intracellularly
137
rating scale for depression
PHQ9