psych meds

Question 1

Severe acute mania is treated with?

Answer 1

Lithium or Valproate in addition to antipsycotic

Question 2

Mild to moderate mania treated with?

Answer 2

risperidone or olanzapine monotherapy

Question 3

what is the theraputic window for Lithium?

Answer 3

0.8-1.2 mEq/L

Question 4

Lithium is known to decrease what organ function?

Answer 4

Kidney function over time

Question 5

what meds will increase lithium levels?

Answer 5

ACEI, NSAIDs, thiazides, tetracycline and metro

Question 6

pharmacological treatment for obsessive compulsive disorder is?

Answer 6

SSRIs: sertraline, fluoxetine, fluvoxamine, paroxetine, citalopram, escitalopram

Question 7

how long should pts with OCD and a positive response stay on pharm therapy?

Answer 7

1 year

Question 8

Black box warning for Valproate?

Answer 8

Hepatotoxicity, pancreatitis

Question 9

what is 1st line tx for lowering BP in amphetamine intoxication?

Answer 9

Lorazepam

Question 10

what antidepressant med can cause a faulse positive for amphetamines on urine drug?

Answer 10

bupropion

Question 11

1st line therapy for social anxiety disorder?

Answer 11

SSRI: paroxetine

Question 12

1st line tx in illness anxiety disorderd?

Answer 12

cognitive behavioral therapy

Question 13

management of avoidant personality disorder?

Answer 13

psycotherapy(cognitive behavior therapy and social training), Pharm therapy can be used in adjunct.

Question 14

Zolpidem is what? and used to tx what?

Answer 14

Nonbenzo benzodiazepine, insomnia

Question 15

MOA of benzos

Answer 15

GAba agonits

Question 16

MC manifestation of cannabis withdrawl?

Answer 16

disturbed sleep

Question 17

Meds that can be used in tx sleep-related disturbances after cessation of cannabis?

Answer 17

Zolpidem and nitrazepam

Question 18

what are some atypical anti-dp

Answer 18

mirtazapine, bupropion, agomelatine

Question 19

what are some SNRIs

Answer 19

duloxetine, venlafaxine

Question 20

MAOIs

Answer 20

phenelzine, isocarboxazid

Question 21

tx for ADHD pts with substance abuse Hx?

Answer 21

Atomoxetine(little to no abuse potential)

Question 22

Toluene is a type of what?

Answer 22

inhalant (it is a volital solvent)

Question 23

what can be found in urine drug screen after the use of Toluene?

Answer 23

hippuric acid

Question 24

what is the MOA by which varenicline helps reduce nicotine withdrawl?

Answer 24

it is a partial agonist at the alpha 4 beta 2 nicotinic receptor

Question 25

what med should be monitored to identify low serum bicarb?

Answer 25

topiramate

Question 26

post pardum depression tx?

Answer 26

sertraline, paroxetine, fluvoxamine (safe in breastfeeding)

Question 27

can buproprion be used for smoking cessatipn in prego pts?

Answer 27

NOPE!

Question 28

appropriate tx for acute ETOH with drawl?

Answer 28

IV benzos, IV fluids

Question 29

Clozapine can cause?

Answer 29

agranulocytosis

Question 30

tx for pts that are going thru cannabis withdrawl and have s/s that are affect their work/life?

Answer 30

dronabinol or gabapentin

Question 31

Amantadine is?

Answer 31

nonanticholinergic antiparkinsonian med. can be used in treat parkinsonian extrapyramidal side effects caused by antipsycotic meds

Question 32

what meds are 1st gen antipsycotics?

Answer 32

chlorpromazine, haloperidol, perphenazine, thioxthixene

Question 33

what is alprostadil?

Answer 33

arterial smooth muscle relaxor that can be injected into the penis to cause an erretionc

Question 34

the acute phase of dystonic reaction may be treated with?

Answer 34

diphenhydramine(benzotrpine can alos be used)

Question 35

what is the best clinical intervention for conduct disorder?

Answer 35

multisystemic treatment

Question 36

treatment for cyclothymic disorder?

Answer 36

mood stabilizer: lithium or antipsycotics

Question 37

what are the two MC side effects of mirtazapine?

Answer 37

wt gain, sedation

Question 38

what is 1st line therapy for treatment of bipolar major depression?

Answer 38

quetiapine or lurasidone

Question 39

what SSRI increases the QTc interval the most?

Answer 39

Citalopram

Question 40

Which antipsycotic most commonly causes wt gain?

Answer 40

Olanzapine

Question 41

Ziprasidone is a second gen antipsychotic that carries high risk for?

Answer 41

QT prolongation

Question 42

what is the antidote for benzo intoxication?

Answer 42

flumazenil

Question 43

1st line pharm for binge eating disorder?

Answer 43

SSRIs, topiramate, lisdexamfetamine

Question 44

which two alpha-2 adrenergic agonists may be used to treat impulsivity in conduct disorder?

Answer 44

guanfacine and clonidine

Question 45

what is an alternitive med for ADHD tx?

Answer 45

Atomoxetine ( nonstimulant med, s/e: n/v, wt loss, QT prolongation)

Question 46

prenatal exposure to what agent is consistently associated with the development of attention-def/hyperactivity disorder?

Answer 46

tobacco

Question 47

anorexia pts have an increase or decrease in total WBCs?

Answer 47

decrease (leukopenia) normochromic and normocytic anemias are also seen

Question 48

what is the MOA for first gen antipsychotics?

Answer 48

blockage of dopamine D2 receptors at the postsynaptic membrane

Question 49

which of the following clinical therapys would be most sedaating? cilatopram fluoxetine paroxetine sertraline

Answer 49

paroxetine

Question 50

what SSRI is associated more commonly with n/v?

Answer 50

fluvoxamine

Question 51

what second gen antipsycotic is known to cause elevated serum prolactin levels?

Answer 51

risperidone

Question 52

what is Divalproex?

Answer 52

anticonvulsant, used to treat sz and bipolar disorder

Question 53

in pts with severe aggrestion what medications are indicated for pharm treatment?

Answer 53

second gen antipsycotic: risperidone or quetapine

Question 54

medication for difficulty maintaining sleep?

Answer 54

long acting nonbenzo receptor agonists, dual orexin receptor antagonists and histaimne receptor antagonists (doxepin)

Question 55

sleep initiation med

Answer 55

ramelteon

Question 56

which antihypertensive medications are sometimes used in the tx of PTSD?

Answer 56

alpha blockers and clonidine

Question 57

which teratogenic anticonvulsant has been linked to autism spectrum disorder?

Answer 57

valproate

Question 58

what medication is contraindicaded in treating cocain induced HTN?

Answer 58

propranolol due to unopposed alpha constriction

Question 59

what are s/e of benzotropine?

Answer 59

anticholinergic s/e

Question 60

what are the s/e of clonidine?

Answer 60

sedation, depression, bradycardia, HA, hypotension

Question 61

what is 1st line pharm therapy for bulimia?

Answer 61

fluoxetine(most studied)

Question 62

what is 1st line tx for neuropathic ppain?

Answer 62

duloxetine

Question 63

what is the black box warning for duloxtetine?

Answer 63

increased risk of suicidal thoughts and behavior in peds and young adults

Question 64

what pharm tx of schizotypal personality disorder is aimed at disordered thinging and inattention>

Answer 64

Quetapine