Flashcards in Psych Shelf Deck (102)
What is the difference between acute stress disorder and PTSD?
Acute stress disorder, sx 1mos
What are the 4 symptoms of PTSD?
How to you control symptoms in PTSD?
Psychotherapy!!! numero uno!
- also SSRIs
and if panic attacks: BZDs
In what instances is clozapine (and other atypicals) more effective than the typical antipsychotics?
For the treatment of refractory psychotic disorders
What symptoms are the atypical antipsychotics better at treating?
The negative symptoms
Other than tx psychotic disorders, what else can antipsychotics be used for?
1. Bipolar disorder
5. Transient psychotic symptoms in personality disorders
Antipsychotic potency correlates with what?
Potency of dopaminergic receptor blockade
How is risperidone similar to typical antipsychotics?
very potent blocker of D2 receptor with relatively less serotonin activity
What are the first line agents for acute psychosis?
oral preparations of the atypical antipsychotics
which medication is used in patients who have failed other antipsychotics?
What medications are used for acute agitation in schizophrenia?
Which drugs are approved for the treatment of the manic phase of bipolar disorder?
Which drugs are approved for the treatment of the depressive phase of bipolar disorder?
1. Combination of olanzapine-fluoxetine
Generally speaking, what are the differences in SE profiles of the typical versus atypical antipsychotics?
typicals = movement disorders
atypicals = sedation and metabolic effects
which antipsychotic has the greatest anticholinergic side effects?
- low potency, typical antipsychotics (chlorpromazine)
which antipsychotics lower the seizure threshold?
low potency, typical antipsychotics and clozapine
What antipsychotic causes hypotension and how does it do so?
Risperidone: via alpha receptor blockade
Which antipsychotic is associated with agranulocytosis?
Clozapine! most efficacious but last line drug bc of side effects
Which antipsychotics can cause QT prolongation?
2. Low potentcy typical antipsychotics: thioridazine and mesoridazine
what antipsychotic causes myocarditis and when does it occur?
Clozapine- early in treatment
which antipsychotics are associated with metabolic effects (weight gain, dyslipidemia, and adult onset diabetes)
Olanzapine and closapine
Which antipsychotic can cause pigmentary retinopathy?
Which antipsychotic can increase the risk of developing cataracts?
What are the atypical antipsychotics? (7)
"Oh, Crap! QZ"
What is the difference w hallucinations between schizophrenia and psychosis 2ndary to a general medical condition?
Schizophrenia = mostly auditory hallucinations
2ndary to GMC = prominent hallucinations and delusions, sx only occur during episodes of delirium
Difference between delusion, illusion, and hallucination
Delusion: fixed false belief
Illusion: misinterpretation of an external stimulus
Hallucination: perception in the absence of an external stimulus
What endocrinopathies can cause psychosis?
1. Addison/Cushing disease
Medications that could cause psychosis?? (9 classes)
2. Antiparkinsonian agents
6. Some antihypertensives: beta blockers
What are the 3 phases of schizophrenia?
1. Prodromal: decline in functioning that precedes first psychotic episode
3. Residual: occurs between episodes of psychosis, flat affect, social withdrawal, odd thinking, can continue to have hallucinations