psychiatric disorders

Question 1

What are the Positive symptoms of Schizophrenia?

Answer 1

• Hallucinations
• Disorganised behaviour
• Delusions
• Loss of insight

Question 2

What are Cognitive symptoms of Schizophrenia?

Answer 2

Loss of…

• working memory
• attention
• executive function
• goal directed behaviour
• cognitive flexibility

Question 3

What are Negative symptoms of Schizophrenia?

Answer 3

• flattening of affect
• amotivation
• social withdrawal

Question 4

What are the structural changes in Schizophrenia?

Answer 4

• enlarged ventricles
• cortical loss and thinning (progressive)
• white matter loss
• cortical cellular changes
  
  • -> increased packing of cells
  • -> reduced GABAergic molecular markers
  • -> less dendritic spines

Question 5

Structural and chemical changes in Hippocampus:

Answer 5

• decreased volume of hippocampus (similar to drug abuse patients)
• decreased dentate gyrus size
• sub…….