Psychiatric Meds

Question 1

haloperidol (class, SE)

Answer 1

haldol
class: 1st generation antipsychotic, high potency
SE: EPS

Question 2

fluphenazine (class, SE)

Answer 2

prolixin
class: 1st generation antipsychotic, high potency
SE: EPS

Question 3

chlorpromazine (class, SE)

Answer 3

thorazine
class: 1st generation antipsychotic, low potency
SE: HAM (orthostasis, sedating–avoid in elderly)

Question 4

quetiapine (class, SE)

Answer 4

seroquel
class: 2nd generation antipsychotic
SE: metabolic syndrome, extremely sedating, causes orthostasis

Question 5

olanzapine (class, SE)

Answer 5

zyprexa
class: 2nd generation antipsychotic
SE: metabolic syndrome (worst), sedating

Question 6

ziprasidone (class, SE)

Answer 6

geodon
class: 2nd generation antipsychotic
SE: metabolic syndrome (least), QT prolongation

Question 7

risperidone (class, SE)

Answer 7

risperdal
class: 2nd generation antipsychotic
SE: most “typical” = EPS, metabolic syndrome

Question 8

aripiprazole (class, SE)

Answer 8

abilify
class: 2nd generation antipsychotic
SE: metabolic syndrome (least)
novel MOA = partial DA agonist

Question 9

clozapine (class, SE)

Answer 9

clozaril
class: 2nd generation antipsychotic
SE: metabolic syndrome, agranulocytosis (follow WBC), sezirues, cardiomyopathy, hypotension, drooling
good for TD, decrease suicide, most effective but most dangerous

Question 10

1st generation antipsychotic SE

Answer 10

high potency more EPS

low potency more HAM

Question 11

2nd generation antipsychotic SE

Answer 11

metabolic syndrome

Question 12

1st generation antipsychotic MOA

Answer 12

D2 antagonism

Question 13

2nd generation antipsychotic MOA (+ exception)

Answer 13

D2 and 5HT2A antagonism

Question 14

EPS

Answer 14

acute dystonia, akathisia, parkinsonism, TD, NMS

Question 15

anti-histamine

Answer 15

weight gain, sedation

Question 16

anti-alpha1

Answer 16

orthostasis, cardiac arrhythmias

Question 17

anti-muscarinic (Ach)

Answer 17

delirium, blurred vision, xerostomia, constipation, urinary retention

Question 18

SE of all antipsychotics

Answer 18

all lower seizure threshold, only clozapine known to induce seizures, all potentially prolong QTc

Question 19

lithium (class, SE)

Answer 19

class: mood stabilizer
decreases suicide
SE: neurotoxicity, hypothyroid, DI, leukocytosis, GI
Teratogenicity: Ebsteins Anomaly

Question 20

carbamazepine (class, SE)

Answer 20

class: mood stabilizer
SE: autoinducer at liver (decreases self and VPA), S/J rash, CBC abnl
Teratogenicity: craniofacial defects

Question 21

valproic acid (class, SE)

Answer 21

class: mood stabilizer
SE: hepatitis, CBC abnl, sedation, weight gain
Teratogenicity: neural tube defect

Question 22

2 drugs that decrease suicide risk

Answer 22

Li and clozapine

Question 23

lamotrigine

Answer 23

lamictal
class: mood stabilizer, antiepileptic
great for prevention of depression
SE: S/J rash

Question 24

phenilzine

Answer 24

nardil

class: antidepressant, MAOI

Question 25

tranylcypromise

Answer 25

parnate | class: antidepressant, MAOI

Question 26

selegiline

Answer 26

emsam | class: antidepressant, MAOI

Question 27

amitriptyline

Answer 27

class: antidepressant, TCA | pain syndromes

Question 28

clomipramine

Answer 28

class: antidepressant, TCA | OCD

Question 29

imipramine

Answer 29

class: antidepressant, TCA | enuresis

Question 30

nortriptyline

Answer 30

class: antidepressant, TCA | elderly

Question 31

MAOI MOA, SE

Answer 31

MOA: MAOA--5HT and NE; MAOB--DA SE: NE--> malignant HTN (avoid tyramine-rich food (aged/cured)) 5HT--> serotonin syndrome can overdose

Question 32

TCA MOA, SE

Answer 32

MOA: increase 5HT, NE SE: anti-HAM, torsade can overdose

Question 33

SNRI MOA, SE

Answer 33

MOA: increase 5HT, NE SE: 5HT and NE (diastolic HTN)

Question 34

venlafaxine

Answer 34

class: antidepressant, SNRI

Question 35

duloxetine

Answer 35

class: antidepressant, SNRI

Question 36

SSRI MOA, SE

Answer 36

MOA: 5HT SE: 5HT

Question 37

paroxetine

Answer 37

class: antidepressant, SSRI

Question 38

citalopram

Answer 38

class: antidepressant, SSRI

Question 39

escitalopram

Answer 39

class: antidepressant, SSRI

Question 40

fluoxetine

Answer 40

class: antidepressant, SSRI

Question 41

fluvoxamine

Answer 41

class: antidepressant, SSRI

Question 42

sertaline

Answer 42

class: antidepressant, SSRI

Question 43

buproprion

Answer 43

class: antidepressant, NDRI

Question 44

mirtazapine

Answer 44

class: antidepressant, alpha2 antagonist

Question 45

trazodone

Answer 45

class: antidepressant, SARI

Question 46

nefazodone

Answer 46

class: antidepressant, SARI